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Murphysboro Vacation Rentals

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Check prices for these dates

In two weeks
Jan 9 - Jan 11
In two months
Feb 20 - Feb 22
In three months
Mar 20 - Mar 22
In four months
Apr 17 - Apr 19

Our top choices for Murphysboro vacation rentals

Exterior
Charming 3-bedroom house in tranquil Oraville minutes from Kinkaid Lake.

Charming 3-bedroom house in tranquil Oraville minutes from Kinkaid Lake.

Charming 3-bedroom house in tranquil Oraville minutes from Kinkaid Lake.
2.0 star property
Oraville
10.0 out of 10, Exceptional, (3)
"Comfortable beds clean great place to getaway from everything "
United States
Ryan W.
The price is ￥19,493
￥36,359 total
includes taxes & fees
Dec 27 - Dec 28
Charming 3-bedroom house in tranquil Oraville minutes from Kinkaid Lake.
2 bedrooms
The Lab! Come stay in our brand new space.

The Lab! Come stay in our brand new space.

The Lab! Come stay in our brand new space.
Murphysboro
9.4 out of 10, Exceptional, (19)
"We enjoyed our visit"
United States
Tim P.
The price is ￥18,947
￥31,980 total
includes taxes & fees
Jan 5 - Jan 6, 2026
The Lab! Come stay in our brand new space.
Property grounds
Fishing Cabin next to Kinkaid Lake

Fishing Cabin next to Kinkaid Lake

Fishing Cabin next to Kinkaid Lake
Murphysboro
The price is ￥16,218
￥27,269 total
includes taxes & fees
Dec 27 - Dec 28
Fishing Cabin next to Kinkaid Lake
Property grounds
Primitive campsites, pond, wildlife, campfires

Primitive campsites, pond, wildlife, campfires

Primitive campsites, pond, wildlife, campfires
West Frankfort
8.0 out of 10, Very Good, (1)
The price is ￥3,509
￥7,358 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Primitive campsites, pond, wildlife, campfires
Fridge, microwave, oven, stovetop
Kinkaid Kamper with AC in Oraville - 2 bedrooms for a cozy stay. house mattress

Kinkaid Kamper with AC in Oraville - 2 bedrooms for a cozy stay. house mattress

Kinkaid Kamper with AC in Oraville - 2 bedrooms for a cozy stay. house mattress
Oraville
9.0 out of 10, Wonderful, (2)
"If used for hunting, maybe have a set up for cleaning of game ."
United States
john l.
The price is ￥17,956
￥30,780 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Kinkaid Kamper with AC in Oraville - 2 bedrooms for a cozy stay. house mattress
Dining
Shawnee Wine Trail Farm Stay

Shawnee Wine Trail Farm Stay

Shawnee Wine Trail Farm Stay
Makanda
9.8 out of 10, Exceptional, (10)
"We loved our stay and all the wonderful animals we got to see."
United States
Jasmine B.
The price is ￥7,565
￥19,586 total
includes taxes & fees
Dec 30 - Dec 31
Shawnee Wine Trail Farm Stay
Exterior
Maple Ridge Cabin at Panther's Rest

Maple Ridge Cabin at Panther's Rest

Maple Ridge Cabin at Panther's Rest
Makanda
9.6 out of 10, Exceptional, (23)
"Very nice and peaceful place to stay. Great hiking trails to explore. Host Keith, was very nice guy and very responsive if you need anything. I would highly recommend any of his cabins. "
United States
Belinda
The price is ￥9,108
￥21,221 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Maple Ridge Cabin at Panther's Rest
Fridge, microwave, stovetop, coffee/tea maker
Après Vine Tiny Cabin at Panther's Rest Farm

Après Vine Tiny Cabin at Panther's Rest Farm

Après Vine Tiny Cabin at Panther's Rest Farm
Makanda
10.0 out of 10, Exceptional, (6)
"Staying at this location was wonderful. I loved the open space & the cabin was very welcoming as well as clean & tidy. It was perfect for what I was going for! Thank you"
United States
Christina S.
The price is ￥10,652
￥22,857 total
includes taxes & fees
Dec 30 - Dec 31
Après Vine Tiny Cabin at Panther's Rest Farm
Outdoor dining
3 Bdr Getaway Hunters, Fishermen, Racers Vendors parking for your equipment!

3 Bdr Getaway Hunters, Fishermen, Racers Vendors parking for your equipment!

3 Bdr Getaway Hunters, Fishermen, Racers Vendors parking for your equipment!
Johnston City
7.2 out of 10, Good, (14)
"Really enjoyed the place. Beautiful area, close to town, but away from everything. Very enjoyable. Would absolutely recommend. "
United States
chris p.
The price is ￥11,087
￥26,151 total
includes taxes & fees
Dec 27 - Dec 28
3 Bdr Getaway Hunters, Fishermen, Racers Vendors parking for your equipment!
Children's area
Comfy Clean & Cute

Comfy Clean & Cute

Comfy Clean & Cute
Marion
9.2 out of 10, Wonderful, (29)
"Have stayed here before, we love it, the owners keep in touch with us and make sure that we have everything that we need!"
United States
Carolyn W.
The price is ￥11,696
￥34,802 total
includes taxes & fees
Dec 29 - Dec 30
Comfy Clean & Cute
3 bedrooms, WiFi, bed sheets
All Things Marion-Pet Friendly-Fenced Yard

All Things Marion-Pet Friendly-Fenced Yard

All Things Marion-Pet Friendly-Fenced Yard
2.0 star property
Marion
9.8 out of 10, Exceptional, (8)
"It was a lovely stay for us and our pet. We were visiting relatives in that areaWe were impressed with the backyard and deck. We appreciate the host addressing our concerns would recommend this to our friends relatives."
United States
Julie R.
The price is ￥17,933
￥45,838 total
includes taxes & fees
Dec 30 - Dec 31
All Things Marion-Pet Friendly-Fenced Yard
Exterior
Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!

Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!

Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!
Makanda
9.6 out of 10, Exceptional, (40)
"The cabin was perfect for our 5 nights in the area. There was plenty of room and everything we needed. The pictures online were nice but in real life, it was a real gem. Can't wait to visit again."
United States
Victoria H.
The price is ￥16,997
￥33,215 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!
Exterior
A Little Slice Of Heaven

A Little Slice Of Heaven

A Little Slice Of Heaven
Marion
10.0 out of 10, Exceptional, (70)
"Cozy, comfortable spot to enjoy while exploring the area."
United States
Ariel T.
The price is ￥18,713
￥28,556 total
includes taxes & fees
Jan 5 - Jan 6, 2026
A Little Slice Of Heaven
Exterior
KOOPERS LANDING TREEHOUSE-Brand New build! Casino, Wine trails, National Parks

KOOPERS LANDING TREEHOUSE-Brand New build! Casino, Wine trails, National Parks

KOOPERS LANDING TREEHOUSE-Brand New build! Casino, Wine trails, National Parks
Carterville
9.0 out of 10, Wonderful, (4)
"The house is adorable. Very clean. We stayed for our anniversary and the hosts were sweet to leave us a gift card. Highly recommend. Will be staying here again."
United States
James and Winter C.
The price is ￥23,391
￥39,111 total
includes taxes & fees
Jan 6 - Jan 7, 2026
KOOPERS LANDING TREEHOUSE-Brand New build! Casino, Wine trails, National Parks
Interior
Charming 2-bedroom with AC, WiFi in lovely Jonesboro

Charming 2-bedroom with AC, WiFi in lovely Jonesboro

Charming 2-bedroom with AC, WiFi in lovely Jonesboro
Jonesboro
10.0 out of 10, Exceptional, (4)
"great place. wonderful host."
United States
Carla m.
The price is ￥17,216
￥39,233 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Charming 2-bedroom with AC, WiFi in lovely Jonesboro
Property grounds
Countryside 3-Bedroom Home with Pond near I57/R148 & Lake of Egypt

Countryside 3-Bedroom Home with Pond near I57/R148 & Lake of Egypt

Countryside 3-Bedroom Home with Pond near I57/R148 & Lake of Egypt
Marion
9.6 out of 10, Exceptional, (4)
"Great location. Wish we had more time, loved the house and the area. "
United States
Sue H.
The price is ￥21,079
￥41,068 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Countryside 3-Bedroom Home with Pond near I57/R148 & Lake of Egypt
Outdoor dining
Beautiful location in the secluded woods

Beautiful location in the secluded woods

Beautiful location in the secluded woods
Pomona
10.0 out of 10, Exceptional, (61)
"It was very nice and clean. We really enjoyed staying there. We would love to rent this place again. "
United States
susan B.
The price is ￥13,405
￥25,790 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Beautiful location in the secluded woods
Exterior
3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Makanda
9.8 out of 10, Exceptional, (60)
"The property was extremely clean and well cared for.would definitely stay again. "
United States
Dan H.
The price is ￥14,658
￥28,392 total
includes taxes & fees
Dec 29 - Dec 30
3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Fridge, microwave, oven, stovetop
Fit and Fueled Studio

Fit and Fueled Studio

Fit and Fueled Studio
Pinckneyville
10.0 out of 10, Exceptional, (1)
"Nice place to stay. Kitchen not real well stocked and no WiFi but perfect for what we needed. "
United States
Brandon H.
The price is ￥20,272
￥31,732 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Fit and Fueled Studio
Exterior
The Brunette Treehouse

The Brunette Treehouse

The Brunette Treehouse
Marion
10.0 out of 10, Exceptional, (6)
"We love this little house. The amenities are fantastic and the location is perfect for us. This is our second visit to the treehouses. "
United States
Kerry
The price is ￥17,933
￥34,020 total
includes taxes & fees
Jan 11 - Jan 12, 2026
The Brunette Treehouse
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Murphysboro Hotel Reviews

Drury Inn & Suites Marion

Drury Inn & Suites Marion

10/10 Excellent
"The room was spacious, clean and comfortable. The bathroom was clean and roomy as well. The common area amenities were great including the breakfast and the marketplace. It was an overall great value. The only thing that I would have changed was that the television wasn’t a smart tv. It’s been a long time since I stayed in a hotel where the tv was not WiFi capable and I couldn’t stream or cast to it. The tv in our room was standard with cable channels and only had hdmi adapters. Other than that the stay was great."
Victoria 1-night trip
Posted 22 hours ago
Drury Inn & Suites Marion

Find out more about Murphysboro

Search for holiday rentals in Murphysboro on Expedia! You can easily find your home rentals, villas, holiday apartments in Murphysboro using one of the methods below:

  • View our selection of featured holiday rentals in Murphysboro
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Look no further and take a look at our great range of rental properties in Murphysboro!

Frequently asked questions

Are there vacation rentals in Murphysboro?

Yes, there are vacation rentals near the most popular points of interest in Murphysboro, or you can select a secluded option if you'd like a relaxing place to stay. Murphysboro is known for its restaurants and golf courses. Make sure you have time to check out the parks and museums during your trip.

What are some of the best vacation rentals in Murphysboro?

5 Star Cabin LUXURY AMMENITIES W/POOL HTUB close to WINE TRAIL, HIKING, FISHING: Visitors like this Murphysboro vacation home rental. It is located on the waterfront and has an outdoor pool, a fireplace, and a barbecue grill to put you at ease in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. It offers a patio, a garden, and an arcade game room so you can immerse yourself in your vacation.

How many vacation rentals are there in Murphysboro?

Choose from 14 Expedia vacation rentals in Murphysboro for a memorable vacation.

What’s there to see and do in Murphysboro?

Shawnee National Forest and Parkview Park are a couple of scenic spots to enjoy the outdoors, whereas General John A. Logan Museum is one of the cultural attractions. Other places in town to visit include Kinkaid Village Marina and Lake Murphysboro State Park.

What’s a vacation rental in Murphysboro like?

A vacation rental is a private property you can book for short or long periods in Murphysboro. Vacation rentals offer amenities such as WiFi and washers and dryers so you'll feel just like you're at home. If you're concerned about a clean environment, vacation rentals can offer a sense of safety away from shared hotel elevators and busy front desks while still allowing you the enjoyment of travel. You'll also get more space in a vacation rental than in a hotel, which makes a vacation rental a popular choice for family trips.