Mediterranean Region Vacations from ¥360,142

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The Latest Mediterranean Region Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Vibe Nazionale

Vibe Nazionale

Rome City Centre
¥360,142
per person
Oct 6 - Oct 12
found 24 hours ago
Roundtrip non-stop flight included
Tokyo (HND) to Rome (FCO)
8.4/10 Very Good! (118 reviews)
Apollo Boutique Hotel

Apollo Boutique Hotel

Prati
¥389,756
per person
Oct 6 - Oct 12
found 24 hours ago
Roundtrip non-stop flight included
Tokyo (HND) to Rome (FCO)
9.2/10 Wonderful! (141 reviews)
The room itself is very clean. Very good staff. Wi-Fi is pretty weak. Has a weird system with the room key. You don’t get a card to enter your room anytime you want, you have to leave your key with reception every time you leave. You have to be a trusting person to be able to do that otherwise take any valuables with you if you can. Showers don’t have hot water. Free Breakfast and they gave me free water. Overall decent experience.

Reviewed on Aug 5, 2026

Charme Spagna Boutique Hotel

Charme Spagna Boutique Hotel

Rome City Centre
¥427,940
per person
Oct 6 - Oct 12
found 24 hours ago
Roundtrip non-stop flight included
Tokyo (HND) to Rome (FCO)
9.2/10 Wonderful! (248 reviews)
It’s not the best set up when you arrive, having to take a mini elevator with your luggage already makes you wonder if this is a real hotel, the building doesn’t have any sign outside letting you know that’s your destination, I guess it’s just so old fashioned, but I felt punked for a minute. Our room was two buildings down and it required the front door, gate, another door upstairs before entering an area where your room is, not practical, and you have to go up a. Level to catch another mini elevator to your floor, and then go up walking another level. The AC is very poor in the room, not strong enough at all for the summer heat in Rome. The location is very good and breakfast was fine, cute patio outside to sit and have breakfast. Front desk guys act like this is just a job, not realizing they are the face of the hotel! There is an older gentleman that helps you to your room that is very helpful and hard working, Maybe this is a very old fashioned European way of hosting but I will definitely confirm that it’s a regular hotel setting next time, overall I feel is way to much to just get to your room and not very air conditioned when you get in! Never again!

Reviewed on Aug 25, 2026

Tree Charme Parliament Boutique Hotel

Tree Charme Parliament Boutique Hotel

Rome City Centre
¥416,137
per person
Oct 6 - Oct 12
found 24 hours ago
Roundtrip non-stop flight included
Tokyo (HND) to Rome (FCO)
9.2/10 Wonderful! (52 reviews)
Fantastic hotel, fantastic service !!

Reviewed on Aug 22, 2026

The Fifth Avenue Hotel

The Fifth Avenue Hotel

Manhattan
Save 100% on your flight
¥588,376
per person
Nov 9 - Nov 15
found 1 day ago
Roundtrip flight included
Tokyo (HND) to New York (JFK)
9.6/10 Exceptional! (263 reviews)

Where to stay in Mediterranean Region

Find the best Mediterranean Region areas and neighborhoods for the activities you enjoy most. Learn more about Mediterranean Region
A historic building with a dome and columns, surrounded by pedestrians and parked vehicles.

Rome City Centre

Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Rome City Centre. Top attractions like Trevi Fountain and Piazza Navona are major draws. Catch the metro at Venezia Tram Stop or Arenula-Cairoli Tram Station to see more of the city.

A busy urban street with historic buildings, a clock tower, and a bus.

Madrid Centro

Known for its fascinating museums and acclaimed art galleries, there's plenty to explore in Madrid Centro. Check out top attractions like Gran Via and Puerta del Sol, and jump on the metro at Sol Station or Gran Via Station to see more of the city.

A cobblestone street lined with blue and white buildings, outdoor seating, and bougainvillea flowers.

Alaçatı

Travelers like the cafes in Alaçatı, and Alaçatı Çarşı is a top attraction you might want to visit.

A cityscape with a prominent stone wall and a view of the city below.

Lisbon City Center

Travelers love Lisbon City Center for its popular shops, and you can see more of Lisbon by jumping on the metro at Saldanha Station or Sao Sebastiao Station. You might spend time checking out top sights like Avenida da Liberdade and Rossio Square.

A classical building with columns and statues, surrounded by well-maintained hedges and a clear blue sky.

Athens City Centre

Known for its fascinating museums, charming cafes, and popular shops, there's plenty to explore in Athens City Centre. Top attractions like Syntagma Square and Acropolis are major draws. Catch the metro at Panepistimio Station or Syntagma Station to see more of the city.

Find the Best Mediterranean Region Vacation Packages

Mediterranean Region Hotel Deals

Barcelona Airport Hotel

Barcelona Airport Hotel

Plaza de la Volateria, 3 El Prat de Llobregat
¥23,886
¥27,009 total
Aug 28 - Aug 29
includes taxes & fees
8.6/10 Excellent! (5,143 reviews)
"Fine for an overnight stay to catch an early flight. Staff were friendly. Hotel is a bit tired and could use better lighting, especially in the hallways. Restaurant on site, which is pricey and not a whole lot of selection."

Reviewed on Aug 25, 2026

Barcelona Airport Hotel
Titanic Deluxe Golf Belek

Titanic Deluxe Golf Belek

Kadriye Mah. Canada Cad. 32 K Serik Antalya
9/10 Wonderful! (143 reviews)
"Few things to say: - the room has no mosquito net and we are talking about a hotel near a delta. All the areas are flooded with flies and mosquitoes all the time. - the main restaurant is awful, the food is repetitive and bad tasting, and the place is dirty to a level you can’t even imagine. Very ..."

Reviewed on Jun 30, 2026

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Titanic Deluxe Golf Belek
Hotel101- Madrid

Hotel101- Madrid

Av. de las Fuerzas Armadas, 328 Madrid
Fully refundableReserve now, pay when you stay
¥12,146
¥13,360 total
Aug 31 - Sep 1
includes taxes & fees
9.4/10 Exceptional! (1,253 reviews)
"Outdoor pool was nice but loud because of race track nearby."

Reviewed on Aug 25, 2026

Hotel101- Madrid
See all 821,621 properties in Mediterranean Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Mediterranean Region attractions

The Colosseum in Rome with tourists around.

Colosseum

9.4/10 (44,408 reviews)
A true architectural heavyweight, the 2,000-year-old Colosseum is often considered one of the seven “modern” wonders of the world.
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The Trevi Fountain with sculptures and a large archway.

Trevi Fountain

9.2/10 (43,482 reviews)
Rome is a city abundant in world-class water features, but none more stunning, or more famous, than the Trevi Fountain.
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The Sagrada Familia with a construction crane in the foreground.

Sagrada Familia

9.4/10 (32,723 reviews)
Gaudí’s basilica in the center of Barcelona is an architectural marvel and offers views across the city from eight towering spires.
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A coastal cityscape at dusk with illuminated buildings, a marina, and a prominent fortress-like structure.

Port of Civitavecchia

8.6/10 (754 reviews)
Explore the waterfront in Civitavecchia with a trip to Port of Civitavecchia. Wander the area's seaside or simply enjoy one of its top-notch restaurants.
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A large neoclassical building with columns and the inscription "MAGRIPPA COSTERTIVI".

Pantheon

9.4/10 (37,189 reviews)
One of ancient Rome’s greatest achievements combines momentous history and inspired architecture.
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A cityscape at dusk with historic buildings, a prominent Rolex store, and a busy street.
Photo by National Tourist Office of Spain

Gran Via

9.4/10 (23,455 reviews)
Madrid’s famous shopping strip has boutiques and international brands, an exciting nightlife and an impressive display of early 20th-century architecture.
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A clear turquoise sea, a sandy beach, and a resort with white buildings and palm trees.

Playa de Muro

8.8/10 (1,444 reviews)
A holiday in Platja de Muro, on the island of Mallorca, is the ideal way to spend your next summer. Find out everything it has to offer!
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A bustling urban square with historic buildings, a central mosaic, and pedestrians.

La Rambla

8.8/10 (31,278 reviews)
These lively pedestrian streets in the heart of Barcelona are filled with flower stalls, tapas restaurants and street performers.
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