Mediterranean Region Vacations from ￥160,180
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Save up to ￥45,448 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
The Latest Mediterranean Region Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Los Angeles Deluxe Suites - 2 Bedrooms & 2 Bathrooms
Hollywood
Save 100% on your flight
Price was ￥292,998, price is now ￥160,180 per person
￥160,180
per person
Nov 6 - Nov 12
found 3 hours ago
Roundtrip non-stop flight included
Tokyo (TYO) to Los Angeles (LAX)
9.2/10 Wonderful! (73 reviews)
Beds were good altough the bed covers were stained everything else was good.
Reviewed on Jul 31, 2025
Albergo Etico Roma
Flaminio
Save 100% on your flight
Price was ￥361,470, price is now ￥211,742 per person
￥211,742
per person
Nov 7 - Nov 14
found 3 hours ago
Roundtrip non-stop flight included
Tokyo (HND) to Rome (FCO)
9.6/10 Exceptional! (291 reviews)
Very nice. Would come back! Clean, good breakfast and coffee
Reviewed on Aug 26, 2025
Fairmont Century Plaza Gold Experience
Century City
Save 100% on your flight
Price was ￥428,675, price is now ￥264,510 per person
￥264,510
per person
Oct 1 - Oct 6
found 18 hours ago
Roundtrip flight included
Tokyo (TYO) to Los Angeles (LAX)
9.8/10 Exceptional! (117 reviews)
Alice and the staff in the Gold Experience were beyond helpful. Loved the room, balcony and service overall.
Reviewed on Aug 11, 2025
Hotel Delle Civette
Nomentano
Price was ￥391,362, price is now ￥243,853 per person
￥243,853
per person
Sep 26 - Oct 1
found 1 day ago
Roundtrip non-stop flight included
Tokyo (TYO) to Rome (FCO)
9.4/10 Exceptional! (222 reviews)
Great place to stay, if back in Roma will stay there again!
Reviewed on Aug 1, 2025
Hotel Splendide Royal - The Leading Hotels of the World
Rome City Centre
Save 100% on your flight
Price was ￥721,207, price is now ￥468,029 per person
￥468,029
per person
Sep 26 - Oct 1
found 1 day ago
Roundtrip non-stop flight included
Tokyo (TYO) to Rome (FCO)
9.4/10 Exceptional! (1,000 reviews)
Very friendly, beautiful hotel they got us checked in very quickly even though we were four hours early. It was a great location.
Reviewed on Aug 22, 2025
Where to stay in Mediterranean Region
Find the best Mediterranean Region areas and neighborhoods for the activities you enjoy most. Learn more about Mediterranean Region
Rome City Centre
4.5/5(3,994 area reviews)
Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Rome City Centre. Top attractions like Trevi Fountain and Piazza Navona are major draws. Catch the metro at Venezia Tram Stop or Arenula-Cairoli Tram Station to see more of the city.
Find the Best Mediterranean Region Vacation Packages
Mediterranean Region Hotel Deals
Sofitel Athens Airport
Athens International Airport, Spata-Artemida, Attiki
Fully refundableReserve now, pay when you stay
The price is ￥52,910 per night from Sep 3 to Sep 4
￥52,910
￥62,662 total
Sep 3 - Sep 4
includes taxes & fees
9.4/10 Exceptional! (2,632 reviews)
"The perfect place to stay before your flight"
Reviewed on Aug 25, 2025
Grand Hyatt Barcelona
Plaza de Pio XII, 4, Barcelona
Fully refundableReserve now, pay when you stay
The price is ￥34,180 per night from Aug 28 to Aug 29
￥34,180
￥40,431 total
Aug 28 - Aug 29
includes taxes & fees
9.2/10 Wonderful! (1,307 reviews)
"Having stayed in hotels in 23 different countries over 50 years this was simply one of the best"
Reviewed on Aug 25, 2025
Barcelona Airport Hotel
Plaza de la Volateria, 3, Poligono Mas Blau, El Prat de Llobregat
Fully refundableReserve now, pay when you stay
The price is ￥21,355 per night from Aug 29 to Aug 30
￥21,355
￥23,944 total
Aug 29 - Aug 30
includes taxes & fees
8.6/10 Excellent! (5,025 reviews)
"This place was clean; nice gym and pool. Also great location for travellers. Close to the airport and free shuttle included. They were also great in getting us checked in early, which was very helpful."
Reviewed on Aug 23, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Mediterranean Region
Colosseum
4.5/5(6,605 reviews)
A true architectural heavyweight, the 2,000-year-old Colosseum is often considered one of the seven “modern” wonders of the world.
Sagrada Familia
4.5/5(4,395 reviews)
Gaudí’s basilica in the center of Barcelona is an architectural marvel and offers views across the city from eight towering spires.
Gran Via
4.5/5(1,249 reviews)
Madrid’s famous shopping strip has boutiques and international brands, an exciting nightlife and an impressive display of early 20th-century architecture.
Other vacations you might like
Expedia's Latest Trends
Hotels
- Ritz Paris
- Ave Tennoji Hotel
- Hotel Wedding Venues in Sri Lanka
- Hotels near Intex Osaka
- Villa Fontaine Kobe - Sannomiya
- Izumigo AMBIENT Azumino Hotel
- Route Inn Grantia Akita Spa Resort
- Tsuetate Onsen Hizenya
- Vessel Inn Sapporo Nakajima Park
- Hotels near Statue of Liberty
- Toyoko Inn Fuji Kawaguchiko Ohashi
- Marco Polo Hongkong Hotel
- Hotel Mystays Aomori Station
- Capsule Hotels Toyama Prefecture
- KONJAKUSO Osaka Bentencho "HIKARIYUYA" Projection Mapping SPA
Flights
Activities
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.