Mediterranean Region Vacations from ￥164,461

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The Latest Mediterranean Region Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Relais de la Poste

Relais de la Poste

Rome City Centre
￥164,461
per person
Dec 16 - Dec 20
found 23 hours ago
Roundtrip non-stop flight included
Tokyo (HND) to Rome (FCO)
9.2/10 Wonderful! (734 reviews)
This was a very nice hotel to stay. The staff were great, the rooms were clean and it was centrally located to everything.

Reviewed on Oct 7, 2026

SIRTAJ - Beverly Hills

SIRTAJ - Beverly Hills

South of Wilshire
Save 100% on your flight
￥284,252
per person
Dec 27 - Jan 3
found 1 day ago
Roundtrip flight included
Tokyo (TYO) to Los Angeles (LAX)
8/10 Very Good! (1,016 reviews)
Pace Helvezia

Pace Helvezia

Rome City Centre
￥173,162
per person
Dec 16 - Dec 20
found 23 hours ago
Roundtrip non-stop flight included
Tokyo (HND) to Rome (FCO)
8/10 Very Good! (427 reviews)
Wanted that “old Rome” feel. Got it! Wonderful!!

Reviewed on Sep 16, 2026

Tree Charme Parliament Boutique Hotel

Tree Charme Parliament Boutique Hotel

Rome City Centre
￥181,172
per person
Dec 16 - Dec 20
found 23 hours ago
Roundtrip non-stop flight included
Tokyo (HND) to Rome (FCO)
9.2/10 Wonderful! (62 reviews)
This location is perfectly located in the middle of town for a tourist! Really amazing staff who have great communication via WhatsApp. The breakfasts were fantastic - Highly recommend!! And the dinner onsite is great too. Room was small, but clean and beautifully decorated. Beds were firm but comfortable (think memory foam). The pillows were not good but it’s nominal when everything else is perfect!!!

Reviewed on Oct 7, 2026

Hotel Mancino 12

Hotel Mancino 12

Rome City Centre
￥187,461
per person
Dec 16 - Dec 20
found 23 hours ago
Roundtrip non-stop flight included
Tokyo (HND) to Rome (FCO)
9.2/10 Wonderful! (670 reviews)
STAFF WAS SUPER HELPFUL, SPECIALLY ALESSANDR0 AT THE FRONT DESK

Reviewed on Oct 8, 2026

Where to stay in Mediterranean Region

Find the best Mediterranean Region areas and neighborhoods for the activities you enjoy most. Learn more about Mediterranean Region
A historic building with a dome and columns, surrounded by pedestrians and parked vehicles.

Rome City Centre

Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Rome City Centre. Top attractions like Trevi Fountain and Piazza Navona are major draws. Catch the metro at Venezia Tram Stop or Arenula-Cairoli Tram Station to see more of the city.

Find hotels in Rome City Centre
A busy urban street with historic buildings, a clock tower, and a bus.

Madrid Centro

Known for its fascinating museums and acclaimed art galleries, there's plenty to explore in Madrid Centro. Check out top attractions like Puerta del Sol and Gran Via, and jump on the metro at Sol Station or Gran Via Station to see more of the city.

Find hotels in Madrid Centro
A cityscape with a prominent stone wall and a view of the city below.

Lisbon City Center

Travelers love Lisbon City Center for its popular shops, and you can see more of Lisbon by jumping on the metro at Saldanha Station or Sao Sebastiao Station. You might spend time checking out top sights like Avenida da Liberdade and Rossio Square.

Find hotels in Lisbon City Center
A historic cathedral with a tall bell tower and intricate architectural details.

Downtown Barcelona

La Rambla and Plaça de Catalunya are a few top attractions in Downtown Barcelona. Hop around the city on the metro at Liceu Station or Jaume I Station and check out the area's fascinating museums, stunning cathedral, and popular shops.

Find hotels in Downtown Barcelona
A classical building with columns and statues, surrounded by well-maintained hedges and a clear blue sky.

Athens City Centre

Known for its fascinating museums, charming cafes, and popular shops, there's plenty to explore in Athens City Centre. Top attractions like Acropolis and Syntagma Square are major draws. Catch the metro at Panepistimio Station or Syntagma Station to see more of the city.

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Find the Best Mediterranean Region Vacation Packages

Mediterranean Region Hotel Deals

Hotel101- Madrid

Hotel101- Madrid

Av. de las Fuerzas Armadas, 328 Madrid
Fully refundableReserve now, pay when you stay
￥13,429
￥14,772 total
Nov 1 - Nov 2
includes taxes & fees
Hotel101- Madrid
Barcelona Airport Hotel

Barcelona Airport Hotel

Plaza de la Volateria, 3 El Prat de Llobregat
Fully refundableReserve now, pay when you stay
￥27,082
￥31,194 total
Nov 1 - Nov 2
includes taxes & fees
8.6/10 Excellent! (5,211 reviews)
"I like the airport bus service."

Reviewed on Oct 11, 2026

Barcelona Airport Hotel
Palais Moulay Said & SPA

Palais Moulay Said & SPA

60 Riad Zitoun Lakdim Marrakech Marrakech-Safi
￥18,714
￥21,871 total
Oct 14 - Oct 15
includes taxes & fees
8.8/10 Excellent! (1,014 reviews)
"It was a lovely place stay but we booked a room for 2 People and the bed was honestly tiny and the room was like a cupboard. I think they need to make the room sizes clearer when booking"

Reviewed on Oct 10, 2026

Palais Moulay Said & SPA
See all 807,302 properties in Mediterranean Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Mediterranean Region attractions

The Colosseum in Rome with tourists around.

Colosseum

9.4/10 (44,408 reviews)
A true architectural heavyweight, the 2,000-year-old Colosseum is often considered one of the seven “modern” wonders of the world.
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A cityscape at dusk with historic buildings, a prominent Rolex store, and a busy street.
Photo by National Tourist Office of Spain

Gran Via

9.4/10 (23,455 reviews)
Madrid’s famous shopping strip has boutiques and international brands, an exciting nightlife and an impressive display of early 20th-century architecture.
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The Sagrada Familia with a construction crane in the foreground.

Sagrada Familia

9.4/10 (32,723 reviews)
Gaudí’s basilica in the center of Barcelona is an architectural marvel and offers views across the city from eight towering spires.
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The Trevi Fountain with sculptures and a large archway.

Trevi Fountain

9.2/10 (43,482 reviews)
Rome is a city abundant in world-class water features, but none more stunning, or more famous, than the Trevi Fountain.
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A coastal cityscape at dusk with illuminated buildings, a marina, and a prominent fortress-like structure.

Port of Civitavecchia

8.6/10 (754 reviews)
Explore the waterfront in Civitavecchia with a trip to Port of Civitavecchia. Wander the area's seaside or simply enjoy one of its top-notch restaurants.
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A cityscape with autumn foliage, a prominent building with a clock tower, and a distant mountain range.

La Rambla

8.8/10 (31,278 reviews)
These lively pedestrian streets in the heart of Barcelona are filled with flower stalls, tapas restaurants and street performers.
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A historic church with twin bell towers and a central obelisk, surrounded by a crowd of people on the steps.

Spanish Steps

9.2/10 (37,743 reviews)
A monumental stairway with a monumental past, the Spanish Steps are literally and figuratively at the heart of Rome.
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A large neoclassical building with columns and the inscription "MAGRIPPA COSTERTIVI".

Pantheon

9.4/10 (37,189 reviews)
One of ancient Rome’s greatest achievements combines momentous history and inspired architecture.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.