Lake Nona Medical City Vacations from ￥228,381

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The Latest Lake Nona Medical City Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Seasons Florida Resort

Seasons Florida Resort

2 out of 5
Price was ￥279,216, price is now ￥228,381 per person
￥228,381
per person
Sep 19 - Sep 25
found 18 hours ago
Roundtrip non-stop flight included
Tokyo (HND) to Orlando (MCO)
9/10 Wonderful! (3,664 reviews)

Margaritaville Cottages Orlando by Vstays with H2O Waterpark

Margaritaville Cottages Orlando by Vstays with H2O Waterpark

4 out of 5
Price was ￥495,274, price is now ￥326,392 per person
￥326,392
per person
Sep 19 - Sep 25
found 18 hours ago
Roundtrip non-stop flight included
Tokyo (HND) to Orlando (MCO)
9.2/10 Wonderful! (1,003 reviews)

The Delaney Hotel

The Delaney Hotel

3.5 out of 5
South Orange
Price was ￥345,118, price is now ￥259,066 per person
￥259,066
per person
Sep 19 - Sep 25
found 18 hours ago
Roundtrip non-stop flight included
Tokyo (HND) to Orlando (MCO)
9.6/10 Exceptional! (1,150 reviews)

Lifetime of Vacations Resort

Lifetime of Vacations Resort

3 out of 5
Price was ￥296,484, price is now ￥232,618 per person
￥232,618
per person
Sep 20 - Sep 27
found 1 day ago
Roundtrip non-stop flight included
Tokyo (TYO) to Orlando (MCO)
9.4/10 Exceptional! (172 reviews)
Older room but clean and close to golf!

Reviewed on Jul 12, 2026

Evermore Orlando Resort

Evermore Orlando Resort

4 out of 5
Price was ￥565,597, price is now ￥445,626 per person
￥445,626
per person
Sep 20 - Sep 27
found 1 day ago
Roundtrip non-stop flight included
Tokyo (TYO) to Orlando (MCO)
9.6/10 Exceptional! (717 reviews)

Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona Medical City
A traditional Japanese torii gate with a dragon sculpture in front, overlooking a calm lake with a distant view of a spherical building.

Bay Lake

4 out of top 10 points of interest in this area

Home to all four Walt Disney World Resort theme parks and one water park, this city offers endless entertainment, including Disney's Fort Wilderness Resort & Campground and Magnolia and Palm Golf Courses.

Find hotels in Bay Lake

Lake Nona Medical City Hotel Deals

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

4 out of 5
8800 Vistana Centre Dr Orlando FL
Fully refundableReserve now, pay when you stay
The price is ￥27,446 per night from Jul 21 to Jul 22
￥27,446
￥30,877 total
Jul 21 - Jul 22
includes taxes & fees
9.2/10 Wonderful! (6,146 reviews)
"I think you guys should have breakfast every day"

Reviewed on Jul 18, 2026

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando
Rosen Inn Lake Buena Vista

Rosen Inn Lake Buena Vista

3.5 out of 5
8442 Palm Parkway Orlando FL
Fully refundableReserve now, pay when you stay
The price is ￥10,054 per night from Aug 9 to Aug 10
￥10,054
￥11,309 total
Aug 9 - Aug 10
includes taxes & fees
Rosen Inn Lake Buena Vista
Universal's Cabana Bay Beach Resort

Universal's Cabana Bay Beach Resort

3.5 out of 5
6550 Adventure Way Orlando FL
Fully refundableReserve now, pay when you stay
The price is ￥24,360 per night from Jul 19 to Jul 20
￥24,360
￥27,405 total
Jul 19 - Jul 20
includes taxes & fees
9/10 Wonderful! (7,231 reviews)
"Good value for the money. Food prices are high in the restaurant. Thin walls. You could hear people talking easy in other rooms"

Reviewed on Jul 18, 2026

Universal's Cabana Bay Beach Resort
See all 27,684 properties in Lake Nona Medical City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Lake Nona Medical City vacation package cost?
The cheapest Lake Nona Medical City package is ￥228,381, so your dream trip can become a reality — without burning a hole in your pocket. Combine flights, hotels and car rentals to tailor make a package that suits your travel style.
How do I get a cheap travel package to Lake Nona Medical City?
Find flights that fit your busy schedule, add a hotel to your booking and watch the savings rack up with a Lake Nona Medical City vacation package. It's as easy as that! From flights and hotels to tours and rental cars, Expedia makes traveling cheap and easy. And with more than 550 air carriers and 1,000,000 hotel options globally to pick from, you won't be short of choice.
Where should I stay in Lake Nona Medical City?
With loads to explore in Lake Nona Medical City, it'd be convenient for you to stay close to its attractions. Nemours Childrens Hospital, VA Medical Center at Lake Nona and University of Central Florida College of Medicine are some fascinating ones to add to your to-do list.
What are the top hotels in Lake Nona Medical City?
Make a reservation at Residence Inn Orlando Lake Nona. It's one of the area's most sought-after properties. Another reputable option in Lake Nona Medical City is Courtyard Orlando Lake Nona.
How far in advance should I book my Lake Nona Medical City vacation?
It depends on the airline, but you can generally look up international fares on Expedia up to a year in advance. While it's generally a good idea to book ahead of time, lucky customers occasionally score a cheaper ticket just weeks prior to the date of departure.
What does an Expedia Lake Nona Medical City travel package include?
Expedia has everything you need to organize your Lake Nona Medical City getaway, but what goes into your package is totally up to you. Choose from a combination of hotels, rental cars and flights. In search of some experiences or tours to keep you busy? Once you've made your booking, you can add them too. Whatever your budget or style, there's a deal to match your needs.
What should I know before booking a Lake Nona Medical City travel package?
Locking in all the parts of your escape together is a great way to save. Combine your airfares, rental cars and hotels into one package. But hotels aren't your only option. Expedia has all types of properties, including vacation rentals like beachside villas and city apartments. The list goes on!
Can I choose my airline with a Lake Nona Medical City Expedia vacation package?
Yes — and it's simple too. Expedia has access to more than 550 partner airlines worldwide. Our vacation packages give you the freedom to take your pick of available flight, hotel or activity options that fit your needs.
If I'm not able to travel, can I cancel my Lake Nona Medical City vacation package?
Don't worry if you're rethinking your Lake Nona Medical City vacation package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur a fee from your airline, hotel or car rental company. We know life can throw the occasional spanner in the works, so look up our Customer Service Portal if that occurs. When you're ready to make changes, we'll be here to help.

Things to do

Universal Orlando Resort Express Passes

Universal Orlando Resort Express Passes

￥32,889
per traveler
80% of travellers recommend
Universal Orlando Resort Express Passes
Universal Orlando Resort Theme Park Tickets

Universal Orlando Resort Theme Park Tickets

￥26,829
per adult
78% of travellers recommend
Universal Orlando Resort Theme Park Tickets
Aquatica Orlando

Aquatica Orlando

￥9,426
per traveler
84% of travellers recommend
Aquatica Orlando
See all activities in Orlando
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.