
Lake Nona Medical City Vacations from ¥48,416
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The Latest Lake Nona Medical City Vacation Packages
Price found within the past 48 hours. Click for updated prices.

Meliá Orlando Celebration
Price was ¥68,473, price is now ¥48,416 per person
¥48,416
per person
Feb 21 - Feb 23
found 14 hours ago
Roundtrip non-stop flight included
Cleveland (CLE) to Orlando (MCO)
8.6/10 Excellent! (1,549 reviews)
I've stayed at the Melia a number of times over the past 10 years or so, and they have done a lot of work on the building and surrounding property and pool area.
My stay was great. The staff here are always lovely, Liam at the front desk was warm and welcoming, and very kind when we were stuck by a snowstorm and were hoping to extend our stay (we couldn't, they were full but he made other local recommendations).
The resort fees have become a little steep, particularly because we are often not in the hotel to take advantage of their one hour happy hour between 4:30 and 5:30 and don't make use of the Advent Health Centre spa/gym.
The only constructive feedback I have is that our balcony wasn't really usable and we usually enjoy sitting on the Melia balconies for fresh air in the mornings of our stays. We were in an accessible room on the first floor, and you can go out on the balcony, but you're treated to a view of the privacy wall on the bar patio. It blocks all of the natural light into the suite, it's like looking at a brick wall. I haven't chosen an accessible room at the Melia before, but someone had an injury, so we wanted the roll in shower. It's very strange and hopefully not a reflection of how they prioritize the experience of their guests with accessibility requirements.
Reviewed on Jan 7, 2026

Margaritaville Cottages Orlando with H2O Waterpark by Vstays
Price was ¥270,777, price is now ¥189,642 per person
¥189,642
per person
Feb 20 - Feb 23
found 13 hours ago
Roundtrip non-stop flight included
Tokyo (TYO) to Orlando (MCO)
9.2/10 Wonderful! (1,001 reviews)
The place was awesome we were close to the pool and everything worked out well. There was an issue with the tv s, we could not get them to work, but that wasn’t why we were there so not a big deal
Reviewed on Jan 2, 2026

The Delaney Hotel
South Orange
Price was ¥124,946, price is now ¥89,658 per person
¥89,658
per person
Feb 20 - Feb 22
found 14 hours ago
Roundtrip non-stop flight included
Cleveland (CLE) to Orlando (MCO)
9.6/10 Exceptional! (1,002 reviews)
Very nice small hotel. The Delaney Tavern was a great hotel restaurant to visit and the overall hospitality of the whole property was fantastic!
Reviewed on Jan 1, 2026

Silver Lake Resort
Price was ¥66,515, price is now ¥49,446 per person
¥49,446
per person
Feb 21 - Feb 23
found 14 hours ago
Roundtrip non-stop flight included
Cleveland (CLE) to Orlando (MCO)
8.4/10 Very Good! (1,226 reviews)
This resort is amazing. The activity room staff especially were great! We stayed for 10 nights and enjoyed every minute of if.
Reviewed on Jan 5, 2026

Florida Hotel & Conference Center in the Florida Mall
Price was ¥98,982, price is now ¥73,720 per person
¥73,720
per person
Feb 20 - Feb 22
found 14 hours ago
Roundtrip non-stop flight included
Cleveland (CLE) to Orlando (MCO)
9.2/10 Wonderful! (2,232 reviews)
Great location with mall access and awesome outdoor heated pool and hot tub.
I wiyld definitely stay here again.
Reviewed on Jan 5, 2026
Where to stay in Lake Nona Medical City
Find the best Lake Nona Medical City areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona Medical City

International Drive District
1 out of top 10 points of interest in this area
Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.
Lake Nona Medical City Hotel Deals

Universal's Cabana Bay Beach Resort
6550 Adventure Way Orlando FL
Fully refundableReserve now, pay when you stay
The price is ¥20,829 per night from Jan 13 to Jan 14
¥20,829
¥23,433 total
Jan 13 - Jan 14
includes taxes & fees
8.8/10 Excellent! (6,006 reviews)
Room was great, loved the pool and lazy river, great location, food options, and transportation. We will be staying here again!
Reviewed on Jan 6, 2026

Wyndham I-Drive Avanti Resort & Conference Center
6515 International Drive Orlando FL
Fully refundableReserve now, pay when you stay
The price is ¥9,758 per night from Jan 11 to Jan 12
¥9,758
¥14,149 total
Jan 11 - Jan 12
includes taxes & fees
7.2/10 Good! (4,065 reviews)
everything
Reviewed on Jan 6, 2026

Rosen Inn at Pointe Orlando
9000 International Drive Orlando FL
Fully refundableReserve now, pay when you stay
The price is ¥11,179 per night from Jan 26 to Jan 27
¥11,179
¥12,576 total
Jan 26 - Jan 27
includes taxes & fees
8.4/10 Very Good! (5,547 reviews)
Friendly staff
Reviewed on Jan 5, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Discover the most popular places to visit in Lake Nona Medical City
University of Central Florida College of Medicine
5/5(1 review)
Enjoy the collegiate vibe at University of Central Florida College of Medicine as part of your travels around Orlando. Stroll along the seaside in this family-friendly area, or check out its top-notch restaurants.
Sanford-Burnham Medical Research Institute
5/5(1 review)
Though Sanford-Burnham Medical Research Institute might be what brings you to town, perhaps you'll have a chance to explore more of Orlando while you are here.
Things to do

Universal Orlando Resort Express Passes
¥25,011
per traveler
86% of travellers recommend

Universal Orlando Resort Theme Park Tickets
¥24,583
per adult
78% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.




