Find hotels in La Plata, MO from ¥10,461

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Our top choices for La Plata hotels

Depot Inn and Suites

Depot Inn and Suites
3.5 star property
La Plata
9.8 out of 10, Exceptional, (614)
This Art Deco hotel offers morning swims in the indoor pool and a winery experience. Located near La Plata Station, guests enjoy free breakfast, WiFi, and parking. The family-friendly rooms include refrigerators and microwaves, with helpful staff ready to assist.

"Fantastic stay, highly recommended .... will definitely be coming back."
United States
Chad
Depot Inn and Suites

Super 8 by Wyndham Kirksville-University Area

Super 8 by Wyndham Kirksville-University Area
2.5 star property
Kirksville
9.0 out of 10, Wonderful, (147)
Connected to a golf course in Kirksville, this hotel offers complimentary WiFi, daily buffet breakfast, and free parking. Thousand Hills State Park is nearby, with La Plata Station just 13 minutes away.

"The rooms were clean and the breakfast bar is outstanding staff was very friendly and helpful "
United States
Bill
The price is ¥10,128
¥11,378 total
includes taxes & fees
Dec 21 - Dec 22
Super 8 by Wyndham Kirksville-University Area

Days Inn by Wyndham Kirksville

Days Inn by Wyndham Kirksville
2.0 star property
Kirksville
6.6 out of 10, (1001)
Enjoy a tranquil escape at this Kirksville hotel offering an indoor pool and convenient bar. Located near Thousand Hills State Park with complimentary breakfast, WiFi, and parking. Guests consistently praise the helpful staff and immaculate accommodations.

"Breakfast was great enjoyed the pool"
United States
Dara
The price is ¥10,146
¥11,397 total
includes taxes & fees
Dec 16 - Dec 17
Days Inn by Wyndham Kirksville

Hampton Inn Kirksville

Hampton Inn Kirksville
2.5 star property
Kirksville
9.2 out of 10, Wonderful, (571)
Located near Thousand Hills State Park, this welcoming hotel offers free breakfast, WiFi, and parking. Enjoy morning swims in the indoor pool or workouts in the fitness center. Business-friendly amenities and a helpful team ensure a comfortable stay in Missouri.

"Clean and very friendly staff"
United States
David
The price is ¥17,326
¥19,635 total
includes taxes & fees
Dec 21 - Dec 22
Hampton Inn Kirksville

Super 8 by Wyndham Macon

Super 8 by Wyndham Macon
2.0 star property
Macon
7.8 out of 10, Good, (669)
Wake up to a quiet, comfortable stay at this Macon motel offering complimentary on-the-go breakfast between 6:00 AM and 10:00 AM. Enjoy free WiFi and parking while exploring nearby Stephen's Park and Jackson Street Park.

"quiet location, comfortable rooms."
United States
laszlo
The price is ¥11,218
¥12,239 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Super 8 by Wyndham Macon

Holiday Inn Express & Suites Kirksville - University Area by IHG

Holiday Inn Express & Suites Kirksville - University Area by IHG
2.5 star property
Kirksville
9.2 out of 10, Wonderful, (509)
Located near a train station in Kirksville, this hotel offers a refreshing indoor pool and 24-hour fitness center. Guests praise the complimentary breakfast and attentive staff. Thousand Hills State Park is nearby, with free WiFi and parking included.

"Excellent service and stay"
United States
Taylor
The price is ¥17,295
¥19,600 total
includes taxes & fees
Dec 21 - Dec 22
Holiday Inn Express & Suites Kirksville - University Area by IHG

OYO Travelier Motel

OYO Travelier Motel
2.5 star property
Macon
7.6 out of 10, Good, (384)
Located near Jackson Street Park, this hotel offers free continental breakfast, WiFi and valet parking. Travelers love the friendly staff. Stephen's Park is just a short distance away. Enjoy a convenient Macon stay without breaking the bank.

"Room was great service was awesome "
United States
Dara
The price is ¥8,588
¥10,461 total
includes taxes & fees
Jan 1 - Jan 2, 2026
OYO Travelier Motel

Knights Inn Kirksville

Knights Inn Kirksville
1.5 star property
Kirksville
7.2 out of 10, Good, (250)
Tranquil accommodations with unique layout ensure no neighbors above or below for ultimate relaxation. Free parking and in-room coffeemakers add convenience, while nearby natural attractions await your exploration.

"Cozy and cool."
United States
Lois
The price is ¥10,595
¥11,900 total
includes taxes & fees
Dec 15 - Dec 16
Knights Inn Kirksville

Americas Best Value Inn & Suites Macon at Sunset Dr

Americas Best Value Inn & Suites Macon at Sunset Dr
2.0 star property
Macon
6.6 out of 10, (334)
This business-friendly motel offers a restaurant for meals and a bar/lounge to unwind after exploring nearby Long Branch State Park. Free parking, 24-hour front desk, and a business center provide essential conveniences for your stay.

"Was clean had comfortable bed. Older motel but in decent shape. Would stay there again "
United States
Paul
The price is ¥10,019
¥10,705 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Americas Best Value Inn & Suites Macon at Sunset Dr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place to stay in La Plata?
Based on our traveler data, Depot Inn and Suites is one of the top choices for your stay. This hotel offers a winery and free breakfast. Other good options for your stay in the area are Super 8 by Wyndham Kirksville-University Area and Baymont by Wyndham Kirksville University Area. See all available top hotels, or vacation rentals in La Plata.
What are some of the best vacation rentals that La Plata has to offer?
Charming 2-bedroom House with WiFi, Patio/Grill, W&D, & Complimentary Breakfast: This highly rated vacation home rental in La Plata offers an indoor pool, a fireplace, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. You can relax into your vacation with a patio and a pool table. See all vacation rentals in La Plata.
If I need to cancel my hotel reservation in La Plata, will I receive a refund?
Yes, most hotel room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in La Plata.
Where can I learn more about changing or cancelling my trip to La Plata?
For more details about updating your trip to La Plata or cancelling it, click here.
What is the best accommodation for staying close to Lambert-St. Louis International Airport (STL)?
Marriott St. Louis Airport is a popular 3.5-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.5 km) from Lambert-St. Louis Intl. Airport. Other good choices within close proximity to the airport include Pear Tree Inn Airport - St. Louis - St. Ann, MO and Drury Inn & Suites St. Louis Airport.
What is staying in La Plata like?
Visitors can enjoy all that La Plata has to offer including the university setting, golf courses, and coffeehouses. Tourists can also enjoy the city's restaurants and museums. In La Plata, there are 2 hotels and other accommodations to choose from. Find out more about La Plata.
What is there to see in La Plata?
A favorite place to visit is La Plata Golf Course. You'll also find Thousand Hills State Park and Long Branch State Park in the area. Check out what more to see and do in Expedia's La Plata guide.
How can I get around La Plata?
If you want to venture outside of the area, ride aboard one of the trains from La Plata Station. If you want to venture out around the area, you may want a rental car in La Plata for your journey.
What's the weather like in La Plata?
The hottest months are usually July and August with an average temp of 73°F, while the coldest months are January and February with an average of 32°F. The snowiest months in La Plata are January, November, February, and December, with each month seeing an average of 5 inches of snowfall.

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