A sunset over a mountainous landscape with scattered clouds.

La Mesa Vacation Rentals

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Check prices for these dates

In two weeks
Oct 30 - Nov 1
In two months
Dec 11 - Dec 13
In three months
Jan 8 - Jan 10
In four months
Feb 5 - Feb 7

Our top choices for La Mesa vacation rentals

A hotel reception area with a counter, a digital tablet, and a poster on the wall.

1. 2 Queen Beds | Mini Fridge

2 Queen Beds | Mini Fridge
La Mesa
The price is ￥20,222
￥22,272 total
includes taxes & fees
Oct 18 - Oct 19
2 Queen Beds | Mini Fridge
A hotel room with two beds, a large mirror, and a wooden floor.

2. 2 Queen Beds | Non-Smoking, Micfridge

2 Queen Beds | Non-Smoking, Micfridge
La Mesa
10.0 out of 10, Exceptional, (47 reviews)
"We found the space decent for our small group and liked having parking on site."
United States
Anonymous traveler
The price is ￥16,915
￥18,607 total
includes taxes & fees
Oct 21 - Oct 22
2 Queen Beds | Non-Smoking, Micfridge
A neatly made bed with white bedding, a bedside table with a digital thermometer, two lit candles, a blue and white patterned lamp, and a small potted plant.

3. Entire Private Home w/ 4BR 3Bath, King Bed, Large Yard & Prime Area, Ranch Style

Entire Private Home w/ 4BR 3Bath, King Bed, Large Yard & Prime Area, Ranch Style
La Mesa
10.0 out of 10, Exceptional, (1 review)
"Great overall experience, clean room."
United States
Warren B.
The price is ￥25,366
￥64,465 total
includes taxes & fees
Oct 18 - Oct 19
Entire Private Home w/ 4BR 3Bath, King Bed, Large Yard & Prime Area, Ranch Style
A modern living room with a sofa, a dining area with bar stools, a kitchen with a refrigerator, and a TV mounted on the wall.

4. Entire Private House with 4 Beds, Gated Yard, Parking, Ranch Style in La Mesa

Entire Private House with 4 Beds, Gated Yard, Parking, Ranch Style in La Mesa
La Mesa
The price is ￥28,185
￥65,205 total
includes taxes & fees
Nov 1 - Nov 2
Entire Private House with 4 Beds, Gated Yard, Parking, Ranch Style in La Mesa
A modern living room with a flat-screen TV, a dining area with a white table and green chairs, and a hallway with a door.

5. Entire Private House with 4 Bedroom 3 Bath Ranch Style w Gated Yard, Parking

Entire Private House with 4 Bedroom 3 Bath Ranch Style w Gated Yard, Parking
La Mesa
7.0 out of 10, Good, (2 reviews)
The price is ￥27,057
￥60,942 total
includes taxes & fees
Oct 18 - Oct 19
Entire Private House with 4 Bedroom 3 Bath Ranch Style w Gated Yard, Parking
Interior

6. Mountain top view getaway loft

Mountain top view getaway loft
Casa de Oro-Mount Helix
10.0 out of 10, Exceptional, (1 review)
The price is ￥42,998
￥61,810 total
includes taxes & fees
Nov 15 - Nov 16
Mountain top view getaway loft
A modern kitchen with a large island, stainless steel appliances, and pendant lighting.

7. Modern SD Escape: SDSU/Downtown <10 Min, GameRoom, Fire Pit, Easy Freeway Access

Modern SD Escape: SDSU/Downtown <10 Min, GameRoom, Fire Pit, Easy Freeway Access
La Mesa
9.0 out of 10, Wonderful, (10 reviews)
"We had a wonderful stay! The home is lovely, clean and exactly as described. Jonathan is very nice and easy to communicate with. We loved staying here to celebrate our son’s graduation from SDSU!"
United States
Anonymous traveler
The price is ￥43,227
￥88,037 total
includes taxes & fees
Oct 27 - Oct 28
Modern SD Escape: SDSU/Downtown <10 Min, GameRoom, Fire Pit, Easy Freeway Access
Holiday Home Exterior [summer]

8. 1 Queen Bed | Mini Fridge

1 Queen Bed | Mini Fridge
La Mesa
The price is ￥17,684
￥19,479 total
includes taxes & fees
Oct 28 - Oct 29
1 Queen Bed | Mini Fridge
Holiday Park Facilities and Services

9. Cozy ADA Queen bed|Free Parking|Wifi

Cozy ADA Queen bed|Free Parking|Wifi
La Mesa
The price is ￥17,837
￥19,647 total
includes taxes & fees
Nov 15 - Nov 16
Cozy ADA Queen bed|Free Parking|Wifi
A motel with a covered parking area, multiple cars parked, and a palm tree in the foreground.

10. 1 King Bed | Non-Smoking, Micfridge

1 King Bed | Non-Smoking, Micfridge
La Mesa
10.0 out of 10, Exceptional, (53 reviews)
"We checked in late yet finished paperwork fast within two minutes. The fridge cooled leftovers nicely while near-ground-level parking meant returning late wasn't difficult at all from our spot close to elevators or stairs going up to rooms alike"
United States
Anonymous traveler
The price is ￥15,377
￥16,915 total
includes taxes & fees
Oct 28 - Oct 29
1 King Bed | Non-Smoking, Micfridge
Bedroom

11. Cozy Queen Bed|Free Parking|WiFi

Cozy Queen Bed|Free Parking|WiFi
La Mesa
The price is ￥17,069
￥18,802 total
includes taxes & fees
Oct 28 - Oct 29
Cozy Queen Bed|Free Parking|WiFi
A person in a blue shirt and black jacket walking through a doorway with a child in a red and black shirt.

12. Cozy 2-Bed Queen|Free Parking|Wifi

Cozy 2-Bed Queen|Free Parking|Wifi
La Mesa
The price is ￥19,376
￥21,340 total
includes taxes & fees
Oct 28 - Oct 29
Cozy 2-Bed Queen|Free Parking|Wifi
An inflatable hot tub with water splashing, surrounded by a wooden fence and a house.

13. Private Casita • No Extra Fees • Spa • Beach • AC

Private Casita • No Extra Fees • Spa • Beach • AC
La Mesa
Private Casita • No Extra Fees • Spa • Beach • AC
A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.

14. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (224 reviews)
"Friendly staff!"
United States
Donavin
The price is ￥18,198
￥25,902 total
includes taxes & fees
Oct 26 - Oct 27
City24 Hotel Little Italy Mission Hills
A modern kitchen with white cabinets, a stainless steel refrigerator, and a dining area with a table and chairs.

15. Splendid 1-bedroom apartment in delightful La Mesa with AC and Laundry

Splendid 1-bedroom apartment in delightful La Mesa with AC and Laundry
Mid-City
10.0 out of 10, Exceptional, (7 reviews)
"Great place! Easy to find and access. Good communication from the host. Spacious and had everything we needed. Would visit again!"
United States
Athena M.
The price is ￥13,943
￥25,009 total
includes taxes & fees
Nov 3 - Nov 4
Splendid 1-bedroom apartment in delightful La Mesa with AC and Laundry
A high-rise hotel with multiple floors, a prominent sign at the top, and a well-lit facade.

16. Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,250 reviews)
"Great for traveling families."
United States
Veronica Dangerfield
The price is ￥22,764
￥26,394 total
includes taxes & fees
Nov 15 - Nov 16
Marriott Vacation Club®, San Diego
A room with a dining table, chairs, a fan, and a closed door.

17. Cozy Private Studio in El Cajon

Cozy Private Studio in El Cajon
Mount Helix
8.8 out of 10, Excellent, (29 reviews)
"The host was very helpful"
United States
Bri S.
The price is ￥19,918
￥23,080 total
includes taxes & fees
Oct 18 - Oct 19
Cozy Private Studio in El Cajon
A modern kitchen with white cabinets, stainless steel appliances, and a wooden dining table with upholstered chairs.

18. La Mesa Family Retreat - 20 minutes to Beaches & More!

La Mesa Family Retreat - 20 minutes to Beaches & More!
La Mesa
9.2 out of 10, Wonderful, (13 reviews)
"Owner was gracious to let us stay 2 extra hours"
United States
Janet
The price is ￥23,118
￥80,754 total
includes taxes & fees
Oct 20 - Oct 21
La Mesa Family Retreat - 20 minutes to Beaches & More!
A kitchen with a stove, pots, pans, and various utensils.

19. Lake Murray 3BR Retreat with AC and Skylight

Lake Murray 3BR Retreat with AC and Skylight
La Mesa
10.0 out of 10, Exceptional, (17 reviews)
"Our stay was fantastic and it had everything we need for our 1 week stay. I recommend this location. "
United States
Rosa C.
The price is ￥20,663
￥41,722 total
includes taxes & fees
Oct 19 - Oct 20
Lake Murray 3BR Retreat with AC and Skylight
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Mesa Hotel Reviews

Find out more about La Mesa

Search for holiday rentals in La Mesa on Expedia! You can easily find your home rentals, villas, holiday apartments in La Mesa using one of the methods below:

  • View our selection of featured holiday rentals in La Mesa
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  • Enter your travel dates to view the best deals on holiday rentals in La Mesa while they last

Look no further and take a look at our great range of rental properties in La Mesa!

Frequently asked questions

Are there vacation rentals in La Mesa?

Yes, you can find vacation rentals in La Mesa near La Mesa Memorial Fine Arts Center, or you can choose a secluded option if you'd like a relaxing place to stay. Visitors like the top-notch restaurants and shops in La Mesa. Leave some time to check out the zoo and entertainment venues during your trip.

What are some of the best vacation rentals that La Mesa has to offer?

Luxurious Estate Home-Sumptuous Views - Resort Like!!!: This La Mesa vacation home rental offers a balcony, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. You and your friends and family can relax into your vacation with amenities like a hot tub.

How many vacation rentals are there in La Mesa?

With 65 Expedia vacation rentals, you're sure to find just the right place for your La Mesa stay.

What can I see and do in La Mesa?

While exploring the area, visit family-friendly sights like San Diego Zoo, or get outside and enjoy nature at Mission Bay. While in the area, you can also visit popular places like Petco Park and Port of San Diego.

What are vacation rentals like in La Mesa?

Vacation rentals are privately owned properties you can book for several days or more in La Mesa. Vacation rentals feature amenities such as WiFi and washers and dryers so you'll have everything you need. If you're concerned about a clean environment, vacation rentals can provide a sense of safety away from shared hotel elevators and busy lobbies while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a great choice for families.