Find Resorts & Hotels with Spas in Key Largo, FL

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Check availability on Key Largo Resorts & Hotels with Spas

Our top choices for Key Largo hotels with a spa

Breadfruit Suite | Terrace/patio

Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only
2.5 star property
Rock Harbor
9.8 out of 10, Exceptional, (316 reviews)
  • cleanliness
    Serene spa getaway with tranquil gardens and sunset views from the oceanfront hot tub.
The price is ￥27,002
￥34,842 total
includes taxes & fees
May 19 - May 20
Kona Kai Resort and Gallery - Adults Only
Body treatments, aromatherapy, hot stone massages, deep-tissue massages

Reefhouse Resort & Marina

Reefhouse Resort & Marina
4.5 star property
Key Largo
9.4 out of 10, Exceptional, (1,434 reviews)
  • cleanliness
    Discover tranquil bliss at this waterfront haven with three spa rooms, private beach, and hot stone massages.
The price is ￥41,114
￥52,604 total
includes taxes & fees
May 25 - May 26
Reefhouse Resort & Marina
Sauna, hot tub, steam room, body treatments, hot stone massages

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
8.8 out of 10, Excellent, (1,003 reviews)
  • cleanliness
    Immerse in waterfront wellness at this bay resort with a full-service spa, offering daily Ayurvedic treatments and relaxing garden escapes.
The price is ￥54,448
￥70,004 total
includes taxes & fees
Jun 3 - Jun 4
Playa Largo Resort & Spa, Autograph Collection
In-room dining

Premium Floating Bungalow by Stay Ombi

Premium Floating Bungalow by Stay Ombi
3.5 star property
Key Largo
10.0 out of 10, Exceptional, (2 reviews)
  • cleanliness
    Luxurious massages offered on spa-equipped houseboat with premium floating rooms and serene water access.
The price is ￥155,168
￥174,564 total
includes taxes & fees
May 19 - May 20
Premium Floating Bungalow by Stay Ombi
Fitness facility

Cheeca Lodge & Spa

Cheeca Lodge & Spa
5.0 star property
Matecumbe
9.2 out of 10, Wonderful, (1,314 reviews)
  • cleanliness
    Luxury spa sanctuary with 7 treatment rooms offers beachside massages and tranquil gardens for ultimate rejuvenation.
The price is ￥43,050
￥60,039 total
includes taxes & fees
Jun 3 - Jun 4
Cheeca Lodge & Spa
Deep-tissue massages, Swedish massages, prenatal massages, massages

The Islands of Islamorada

The Islands of Islamorada
4.0 star property
Matecumbe
9.6 out of 10, Exceptional, (75 reviews)
  • cleanliness
    Beachfront spa villa with two pools, massage services, and scenic water walkway offers rejuvenating Florida escape.
The price is ￥91,682
￥111,892 total
includes taxes & fees
May 20 - May 21
The Islands of Islamorada
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Key Largo

Pool
Hot tub

Top Key Largo Hotel Reviews

Reefhouse Resort & Marina

Reefhouse Resort & Marina

10/10 Excellent
"Place was clean and comfortable."
Janetta 3-night trip
Posted 11 hours ago
Reefhouse Resort & Marina

Frequently asked questions

Looking for a spa hotel in Key Largo?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers love the sunsets in Key Largo. Discover the coral reefs and seafood restaurants during your stay. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in Key Largo?
Reefhouse Resort & Marina is a top beachfront spa hotel featuring 3 restaurants, a 24-hour fitness center, a bar, and an outdoor pool. Treat yourself to a facial, body scrub, or detox wrap at By the Bay Spa. Another popular spa hotel in Key Largo is Playa Largo Resort & Spa, Autograph Collection.
How many spa hotels will I find in Key Largo?
Among Expedia's 1310 accommodation options in Key Largo, there are 2 spa hotels.
What's there to see and do in Key Largo?
Enjoy Key Largo and visit Everglades National Park, Jimmy Johnson's Big Chill, and Bluefin Rock Harbor Marina. If you have a bit of extra time while you're in the area, you might want to check out John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.
What is a Key Largo spa hotel?
Spa hotels in Key Largo provide lodging and have an on-site spa offering services including facials and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.