A pier extending into calm waters at sunset with a pink and blue sky.

Find Resorts & Hotels with Spas in Isle of Palms, SC

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Isle of Palms Resorts & Hotels with Spas

Tonight
Oct 19 - Oct 20
Tomorrow
Oct 20 - Oct 21
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Our top choices for Isle of Palms hotels with a spa

A modern retail space with wooden shelves and a central counter.
A resort with multiple buildings, two swimming pools, and a beach area with sun loungers.
A coastal town with beachfront properties and a marina.
A resort with multiple swimming pools, lounge areas, and a fire pit.

1. Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn
Isle of Palms
  • Discover a coastal wellness haven with 14 treatment rooms, heated pools, and serene spa experiences for an unforgettable retreat.
￥23,118
￥31,293 total
includes taxes & fees
Nov 18 - Nov 19
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn
A modern hotel lobby with a reception desk, a seating area, and a visible kitchen in the background.
A coastal hotel with multiple buildings, a beach in the background, and surrounding greenery.
A balcony with a view of the ocean, furnished with yellow chairs and a table, and decorated with flowers and candles.
A coastal town with beachfront properties and a marina.

2. Wild Dunes Resort – Residences at Sweetgrass

Wild Dunes Resort – Residences at Sweetgrass
Isle of Palms
  • Rejuvenate at this coastal retreat with a full-service spa offering deep-tissue massages, body wraps, and facials for ultimate relaxation.
￥33,026
￥44,392 total
includes taxes & fees
Nov 15 - Nov 16
Wild Dunes Resort – Residences at Sweetgrass
A room with two beds covered in beige linens, a bedside table with a lamp, a chair, and a window with blinds.
A beach with palm trees, a thatched-roof structure, and a building with a red roof.
A pool area with lounge chairs and palm trees.
A spacious restaurant with high ceilings, exposed beams, and large windows offering a view of the outdoors.

3. Harborside at Charleston Harbor Resort and Marina

Harborside at Charleston Harbor Resort and Marina
Mount Pleasant
  • Discover a waterfront wellness haven with tranquil spa treatments, couples massage rooms, and stunning sunset views from hot tubs.
￥15,769
￥25,318 total
includes taxes & fees
Nov 17 - Nov 18
Harborside at Charleston Harbor Resort and Marina
A covered outdoor area with a pool, palm trees, and lounge chairs.
A spacious lobby with high ceilings, a grand chandelier, and a central open area leading to a door.
A covered outdoor lounge area with wicker furniture, a pool, and a view of the beach and marina.
A living room with a sofa, a coffee table, and a view of a pool and deck area.

4. The Beach Club at Charleston Harbor Resort and Marina

The Beach Club at Charleston Harbor Resort and Marina
Mount Pleasant
  • Retreat to this harborside haven with couples spa treatments and a heated pool, perfect for unwinding amid beautiful marina views.
￥25,754
￥36,601 total
includes taxes & fees
Nov 17 - Nov 18
The Beach Club at Charleston Harbor Resort and Marina
A grand lobby with a central round table, seating, and potted plants.
A grand interior with ornate chandeliers, classical columns, and a balcony with intricate railings.
A grand hallway with a patterned floor, chandeliers, and seating areas.
A spacious lobby with a grand piano, elegant chandeliers, and plush seating areas.

5. The Francis Marion Hotel

The Francis Marion Hotel
Charleston Historic District
  • Discover a rejuvenating retreat in historic Charleston with aromatherapy massages and full-service spa treatments.
￥33,151
￥37,793 total
includes taxes & fees
Nov 17 - Nov 18
The Francis Marion Hotel
A modern reception area with a marble counter, a round table with a black base, and a large framed picture of horses on a grassy hill.
A kitchen with a brick wall, a built-in cabinet with glass doors, and a refrigerator with a glass door.
A spacious living room with a large window, a fireplace, and a kitchen area with modern appliances.
A staircase with a motorcycle parked at the top, surrounded by lanterns and potted plants.

6. The Restoration

The Restoration
Charleston Historic District
  • Revitalize in Charleston with a rooftop pool, indulgent spa massages, and luxurious rooms featuring rainfall showers and plush bedding.
￥46,932
￥54,813 total
includes taxes & fees
Nov 11 - Nov 12
The Restoration
A spacious hallway with a central round table, flanked by white shelving units with various items.
A spacious, elegantly decorated lounge area with a central bar, plush seating, and large windows.
A grand interior with a curved staircase, a chandelier, and a seating area.
A spacious indoor area with a view of the city, furnished with leather chairs and a bar area.

7. Hotel Bennett

Hotel Bennett
Charleston Historic District
  • Relax in elegance at this Charleston hotel with a full-service spa, rooftop pool, and 5 treatment rooms.
￥90,680
￥103,737 total
includes taxes & fees
Nov 15 - Nov 16
Hotel Bennett
A spacious room with a herringbone floor, a large wooden reception desk, and a wall of shelves displaying various items.
A hotel with a pool, sun loungers, palm trees, and umbrellas.
A balcony with wicker chairs, a table with a bottle and glasses, and a view of the sea.
A room with a sofa, a chair, a table with a vase, and a view of a balcony with a railing.

8. The Cooper

The Cooper
Charleston Historic District
￥99,932
￥123,758 total
includes taxes & fees
Nov 2 - Nov 3
The Cooper
A reception desk with a marble top labeled "RECEPTION" and "The Dewberry" in the background.
A modern bathroom with a freestanding bathtub, two sinks, and a large mirror.
A hotel room with a large bed, a desk with a lamp, a chair, a large mirror, and a window with curtains.
A modern bar area with a long counter, multiple stools, and a large window offering a city view.

9. The Dewberry Charleston

The Dewberry Charleston
Charleston Historic District
  • Indulge in a tranquil spa retreat at this Charleston hotel where 5 treatment rooms offer deep-tissue massages and body wraps.
￥61,470
￥70,438 total
includes taxes & fees
Oct 25 - Oct 26
The Dewberry Charleston
A spacious living room with a fireplace, large windows, and a brick wall.
A brick building with multiple windows, a central door, and potted plants.
A modern kitchen with a dining table, a man pouring a drink, and a woman sitting.
Private kitchen

10. The Pinch Hotel

The Pinch Hotel
Charleston Historic District
  • Immerse in serene spa treatments at this Charleston hotel with couples' massage rooms and a cozy fireplace lobby.
￥51,056
￥63,615 total
includes taxes & fees
Nov 1 - Nov 2
The Pinch Hotel
View all properties

Choose what matters most at spa hotels in Isle of Palms

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Isle of Palms Hotel Reviews

Frequently asked questions

Looking to vacation at a spa hotel in Isle of Palms?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers love the beaches in Isle of Palms. Enjoy the live music and many popular restaurants during your vacation. Spa hotels are a great way to take a break from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Isle of Palms?
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn is a top beach spa hotel featuring 5 pools, 8 restaurants, 9 bars, and a golf course. Enjoy a facial, body scrub, or detox wrap at The Spa at Sweetgrass. Another popular spa hotel in Isle of Palms is Wild Dunes Resort – Residences at Sweetgrass.
How many spa hotels will I find in Isle of Palms?
Among Expedia's 1725 accommodation options in Isle of Palms, there are 2 spa hotels.
What's there to see and do in Isle of Palms?
Enjoy all that Isle of Palms has to offer and visit Isle of Palms Beach, Isle of Palms Marina, and Front Beach. If you have some spare time during your trip, you might want to check out Wild Dunes Resort Golf Course and Isle of Palms County Park.
What is a Isle of Palms spa hotel?
Spa hotels in Isle of Palms provide lodging and have a full on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.

Explore a world of travel with Expedia