Historic Main Street
Visit Historic Main Street
Plan a trip to see Historic Main Street
The Wildwood Hotel
Reviewed on Aug 25, 2025
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Reviewed on Aug 7, 2025
Popular places to visit
Frontier Park
You can find out about the history of St. Charles with a visit to Frontier Park. Check out the shops and top-notch restaurants in this family-friendly area.
First Missouri State Capitol Historic Site
You can learn about the history of St. Charles when you stop by First Missouri State Capitol Historic Site. Discover the top-notch restaurants and great live music in this family-friendly area.
Missouri Artists on Main
You can spend an afternoon browsing the exhibits at Missouri Artists on Main in St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.
SSM Health St. Joseph Hospital
Though SSM Health St. Joseph Hospital might be what brings you to town, perhaps you'll have a chance to explore more of St. Charles while you are here.
Lewis & Clark Boathouse and Nature Center
You can spend time exploring the galleries in Lewis & Clark Boathouse and Nature Center during your travels in St. Charles. Experience the great live music and acclaimed theater scene in this family-friendly area.
Frenchtown Heritage Museum
You can spend time browsing the exhibits at Frenchtown Heritage Museum during your trip to St. Charles. Check out the shops and top-notch restaurants in this family-friendly area.
Best Lodging Options Near Historic Main Street
Check availability on hotels close to Historic Main Street
Hollywood Casino & Hotel St. Louis
Ameristar Casino Resort and Spa
Country Inn & Suites by Radisson, St. Charles Historic District
The St. Charles Guest House, lovely historic home, fun for families and groups
1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.
HUGE 2 bedroom unit on Main Street
Luxurious couples retreat just steps from Historic Main Street in St. Charles!
The Otter Suite at Divine Otter
The Fox Suite at Divine Otter
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- Vacations and getaways similar to Historic Main Street
- Other Hotels near Historic Main Street, St. Charles Historic District
- Hotels near popular St. Louis Attractions
- More Hotel Options in Historic Main Street
- Busch Stadium
- St. Louis Union Station
- Gateway Arch
- Washington University in St. Louis
- St. Louis Zoo
- Six Flags St. Louis
- City Museum
- Hollywood Casino Amphitheatre
- Barnes Jewish Hospital
- Fox Theater
- Grant's Farm
- Missouri Botanical Gardens and Arboretum
- Anheuser-Busch Brewery
- Route 66 State Park
- Magic House - St. Louis Children's Museum
- 3BR Historic St. Charles, MO-Walking distance to Main Street
- The Owl Suite at Divine Otter
- The Buck Suite at Divine Otter
- The Wild West Getaway- 204-1
- The Bear Suite at Divine Otter
- Scenic South Main Apartment with Breathtaking Views for 3 Guests
- The Hare Suite at Divine Otter
- Walking distance to Historic Main Street, St. Charles, MO
- Western-Themed 2-Bedroom Hideout for Outlaws 204-2
- Relaxing South Main Apartment with Modern Comforts
- Best Western Plus The Charles Hotel