East Main Street, CO
Grand Junction
Visit East Main Street
Popular places to visit
Colorado Mesa University
Enjoy the collegiate vibe at Colorado Mesa University during your stay in Grand Junction. Make time to visit the area's notable monuments, or simply enjoy its top-notch restaurants.
St Mary's Medical Center
Though St Mary's Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of Grand Junction while you are here.
Canyon View Park
Explore the lovely green spaces of Canyon View Park and enjoy the biking trails in Grand Junction. Check out the notable monuments and top-notch restaurants in this family-friendly area.
Two Rivers Convention Center
Learn about the events happening at Two Rivers Convention Center during your trip to Grand Junction. Make time to visit the area's notable monuments, or simply enjoy its lively bars.
Redlands Mesa Golf Club
Enjoy a round of golf in Grand Junction at Redlands Mesa Golf Club. Check out the notable monuments and top-notch restaurants in this family-friendly area.
Grand Junction Motor Speedway
You can take time to visit Grand Junction Motor Speedway during your travels to Grand Junction. Check out the wineries or top-notch restaurants in this family-friendly area.
East Main Street Hotel Deals

Downtown craftsman home with hot tub. 3 blocks from restaurants, shops and bars.
He was extremely easy to work with and very communicative. Lovely home, easy walk to downtown
Reviewed on Dec 16, 2025

Grand Junction Vacation Rental w/ Fire Pit!

Grand Vista Hotel
Clean, basic room which was very close to the airport. They offer shuttle service as well. Paid parking however.
Reviewed on Dec 20, 2025

La Quinta Inn & Suites by Wyndham Grand Junction
Clean room. Lots of noise in the hallway, but my room was pretty well insulated.
Reviewed on Dec 21, 2025

Tru by Hilton Grand Junction Downtown
Traveling across the country it was a convenient place to stay.
Reviewed on Dec 14, 2025

La Quinta Inn & Suites by Wyndham Fruita
Great breakfast and easy to walk to places next door
Reviewed on Dec 18, 2025
Check East Main Street hotel availability
Other neighborhoods around East Main Street

Lincoln Park Historic District
While Lincoln Park Historic District might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Western Colorado Botanical Gardens and Western Colorado Center for the Arts.

Washington Park
While Washington Park isn't home to many top sights, Western Colorado Center for the Arts and Western Colorado Botanical Gardens are some notable places to visit nearby.

7th Street Historic District
When in 7th Street Historic District, you can plan a visit to Western Colorado Center for the Arts and Western Colorado Botanical Gardens, some noteworthy sights in the nearby area.

Downtown
While there might not be top attractions in Downtown, you can explore the larger area and discover places like Western Colorado Botanical Gardens and Bananas Fun Park.

Historic Grand Junction
Historic Grand Junction is popular for its abundant dining options, and you can check out Museum of the West, a top attraction in the neighborhood.

Grandview
While there might not be top attractions in Grandview, you can explore the larger area and discover places like Western Colorado Center for the Arts and Western Colorado Botanical Gardens.
