East Main Street, CO

Grand Junction

Independence Monument in Colorado National Monument

Popular places to visit


East Main Street Hotel Deals

Launch your Colorado adventures – Historic Downtown convenience

Launch your Colorado adventures – Historic Downtown convenience

Grand Junction CO
The price is ¥15,127 per night from Apr 14 to Apr 15
¥15,127
¥31,950 total
Apr 14 - Apr 15
includes taxes & fees
Stay at this vacation home in Grand Junction. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Museum of the West and Western Colorado ...
10/10 Exceptional! (97 reviews)
Clean, really cute, and well decorated

Reviewed on Mar 10, 2026

Launch your Colorado adventures – Historic Downtown convenience
Early Check-in Pet Friendly Grand Lodge Groups and Families

Early Check-in Pet Friendly Grand Lodge Groups and Families

Grand Junction CO
Book a stay at this family-friendly vacation home in Grand Junction. Enjoy free WiFi, a water park, and a garden. Popular attractions Museum of the West and ...
9.8/10 Exceptional! (20 reviews)
Great location, cute property. Had everything we needed.

Reviewed on Mar 14, 2026

Early Check-in Pet Friendly Grand Lodge Groups and Families
Downtown craftsman home with hot tub. 3 blocks from restaurants, shops and bars.

Downtown craftsman home with hot tub. 3 blocks from restaurants, shops and bars.

Grand Junction CO
The price is ¥24,362 per night from Mar 27 to Mar 28
¥24,362
¥52,764 total
Mar 27 - Mar 28
includes taxes & fees
Stay at this vacation home in Grand Junction. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Museum of the West and Western Colorado ...
10/10 Exceptional! (31 reviews)
Great house and even a greater location! We could walk to all activities on Main St. House was very comfortable and we certainly enjoyed the hot tub after a day out visiting all the wineries, shopping, and great food! Thanks to our host, Ron, that answered all my questions!

Reviewed on Mar 3, 2026

Downtown craftsman home with hot tub. 3 blocks from restaurants, shops and bars.
Grand Vista Hotel

Grand Vista Hotel

3.5 out of 5
2790 Crossroads Blvd Grand Junction CO
Book a stay at this business-friendly hotel in Grand Junction. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the restaurant and the helpful ...
8.2/10 Very Good! (3,538 reviews)
Proximity to airport great. Room good size, quiet and great to have a pool and hot tub to relax the night before a travel day

Reviewed on Mar 23, 2026

Grand Vista Hotel
La Quinta Inn & Suites by Wyndham Grand Junction

La Quinta Inn & Suites by Wyndham Grand Junction

3 out of 5
2761 Crossroads Blvd Grand Junction CO
The price is ¥12,680 per night from Mar 30 to Mar 31
¥12,680
¥14,540 total
Mar 30 - Mar 31
includes taxes & fees
Book a stay at this business-friendly hotel in Grand Junction. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (2,865 reviews)
Rooms although outdated are clean. Staff friendly.

Reviewed on Mar 23, 2026

La Quinta Inn & Suites by Wyndham Grand Junction
Clarion Inn Grand Junction

Clarion Inn Grand Junction

2.5 out of 5
755 Horizon Drive Grand Junction CO
The price is ¥13,771 per night from Mar 30 to Mar 31
¥13,771
¥15,789 total
Mar 30 - Mar 31
includes taxes & fees
Book a stay at this business-friendly hotel in Grand Junction. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the ...
8.4/10 Very Good! (1,727 reviews)
I stay here 2 to 3 times a year. The staff is always great rooms are clean breakfast buffet is hearty. The only problem I have: we stay here every time the night before we leave and we catch your shuttle to the airport in the morning. Unfortunately, your shuttle runs every hour which leaves spending ...

Reviewed on Mar 21, 2026

Clarion Inn Grand Junction
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around East Main Street

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Lincoln Park Historic District

While Lincoln Park Historic District might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Elliott Tennis Center and Western Colorado Botanical Gardens.

Lincoln Park Historic District
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Washington Park

While Washington Park isn't home to many top sights, Elliott Tennis Center and Western Colorado Center for the Arts are some notable places to visit nearby.

Washington Park
Bisbee, a historical mining town in South-Eastern Arizona, America, USA. A small town founded in 1880 with amazing old buildings, architecture and a fun travel destination.

7th Street Historic District

When in 7th Street Historic District, you can plan a visit to Western Colorado Center for the Arts and Elliott Tennis Center, some noteworthy sights in the nearby area.

7th Street Historic District
Aerial View of Christmas Lights in Grand Junction, Colorado at Dusk

Downtown

While there might not be top attractions in Downtown, you can explore the larger area and discover places like Western Colorado Botanical Gardens and Bananas Fun Park.

Downtown
Sunrise at the Grand View Overlook in Colorado National Monument

Historic Grand Junction

Historic Grand Junction is popular for its abundant dining options, and you can check out Museum of the West, a top attraction in the neighborhood.

Historic Grand Junction
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Grandview

While there might not be top attractions in Grandview, you can explore the larger area and discover places like Elliott Tennis Center and Western Colorado Center for the Arts.

Grandview


East Main Street, CO