Vacation Rentals in Colleton County

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Top Vacation Rentals in Colleton County

Our top choices for Colleton County vacation rentals

Newly renovated Villa with beautiful views of the Creek & River
Marina

Newly renovated Villa with beautiful views of the Creek & River

9.8 out of 10, Exceptional, (167)
"Diane’s condo was perfect for our needs. We would not hesitate to stay there again or to refer friends who need a smaller space on the island."
Newly renovated Villa with beautiful views of the Creek & River
ULTIMATE BEACH AND GOLF COURSE HAVEN ON SECLUDED EDISTO IN THE WYNDHAM RESORT
Beach towels

ULTIMATE BEACH AND GOLF COURSE HAVEN ON SECLUDED EDISTO IN THE WYNDHAM RESORT

10.0 out of 10, Exceptional, (47)
"Great weekend away in a great area"
ULTIMATE BEACH AND GOLF COURSE HAVEN ON SECLUDED EDISTO IN THE WYNDHAM RESORT
Private Pool at Livin' Is Easy Spacious 5-bedroom in charming Edisto Beach, SC
Microwave, oven, stovetop, dishwasher

Private Pool at Livin' Is Easy Spacious 5-bedroom in charming Edisto Beach, SC

2.0 star property
10.0 out of 10, Exceptional, (20)
"Everything about the house was great. Very well stocked with everything we needed. The location was perfect. 100 yards to the ocean, great pool, and even had enough space to park our boat. We will definitely be back. "
Private Pool at Livin' Is Easy Spacious 5-bedroom in charming Edisto Beach, SC
Oceanfront Showplace - Island Manor
On the beach, sun loungers, beach towels

Oceanfront Showplace - Island Manor

10.0 out of 10, Exceptional, (156)
"Edisto has been our restcation spot for thirty years, and Island Manor has been our our favorite place to stay. The property and host are top notch. I would highly recommend. "
Oceanfront Showplace - Island Manor
Private 4 bedroom home near beach and on golf course
Property grounds

Private 4 bedroom home near beach and on golf course

9.6 out of 10, Exceptional, (141)
"This is a lovely property in a perfect location. We loved watching the wildlife from the porchWe has a wonderful stay. I would recommend and/or stay here again."
Private 4 bedroom home near beach and on golf course
Cozy Edisto Condo-Close to the Beach!
Exterior

Cozy Edisto Condo-Close to the Beach!

9.0 out of 10, Wonderful, (71)
"Very relaxing cottage feel. Parklike setting with a lot of shade is perfect for walks. I recommend without reservation. "
The price is ￥13,233
￥27,171 total
includes taxes & fees
Sep 3 - Sep 4
Cozy Edisto Condo-Close to the Beach!
CHARMING COASTAL COTTAGE, SWIMMING, OFFSHORE FISHING, TURTLE TOURS, GOLF, BIKING
Indoor pool, outdoor pool

CHARMING COASTAL COTTAGE, SWIMMING, OFFSHORE FISHING, TURTLE TOURS, GOLF, BIKING

10.0 out of 10, Exceptional, (23)
"It was a great spot for 2 people, and was in a good, quiet location! "
The price is ￥16,908
￥43,473 total
includes taxes & fees
Sep 13 - Sep 14
CHARMING COASTAL COTTAGE, SWIMMING, OFFSHORE FISHING, TURTLE TOURS, GOLF, BIKING
Golf cart included “Only Young Once” 900 feet from 🏖️
Sun loungers, beach towels

Golf cart included “Only Young Once” 900 feet from 🏖️

9.8 out of 10, Exceptional, (11)
"Great place very clean and right at beach access."
Golf cart included “Only Young Once” 900 feet from 🏖️
The Sandy Pineapple! Direct Edisto Beach oceanfront with 4 bedrooms and 2 baths
Outdoor dining

The Sandy Pineapple! Direct Edisto Beach oceanfront with 4 bedrooms and 2 baths

10.0 out of 10, Exceptional, (23)
"This is a great house with an amazing view. Walking distance to grocery store and restaurants. "
The Sandy Pineapple! Direct Edisto Beach oceanfront with 4 bedrooms and 2 baths
Perfect beach and golf getaway!
Dining

Perfect beach and golf getaway!

9.6 out of 10, Exceptional, (54)
"We were here to attend a wedding, and was nice and convenient."
Perfect beach and golf getaway!
2nd row Ocean Views 4br 3ba Sleeps 12, '25 Pool Amenity Card, linens included
Beach nearby, sun loungers

2nd row Ocean Views 4br 3ba Sleeps 12, '25 Pool Amenity Card, linens included

10.0 out of 10, Exceptional, (51)
"We loved it! Kids loved pool table"
2nd row Ocean Views 4br 3ba Sleeps 12, '25 Pool Amenity Card, linens included
Our Little Piece of Heaven
Outdoor dining

Our Little Piece of Heaven

10.0 out of 10, Exceptional, (80)
"This house was perfect for our family’s stay at the beach. We were very pleased with the cleanliness and amenities, and the kids loved the puzzles, games & toys! We hope to stay here again in the future!"
Our Little Piece of Heaven
Jungle House/ Pet Friendly/ Luxury New Edisto Home
Fridge, microwave, oven, stovetop

Jungle House/ Pet Friendly/ Luxury New Edisto Home

10.0 out of 10, Exceptional, (13)
"It was the perfect space for a small family beach get away"
The price is ￥30,876
￥86,833 total
includes taxes & fees
Sep 29 - Sep 30
Jungle House/ Pet Friendly/ Luxury New Edisto Home
The Kerryman - OVERLOOKS BAY CREEK MARINA! New master BR mattress March 2025
Property grounds

The Kerryman - OVERLOOKS BAY CREEK MARINA! New master BR mattress March 2025

9.6 out of 10, Exceptional, (18)
"Thoroughly enjoyed our stay. Condo was nice and very clean. Beautiful view of the bay with gorgeous sunsets! Can't wait to go back again. "
The Kerryman - OVERLOOKS BAY CREEK MARINA! New master BR mattress March 2025
4 Bedroom 2 Bath Ocean Front Vacation Rental on Edisto Beach
Property grounds

4 Bedroom 2 Bath Ocean Front Vacation Rental on Edisto Beach

9.8 out of 10, Exceptional, (41)
"This was a wonderful clean place. Beach front and the back deck was amazing. I loved this place. "
4 Bedroom 2 Bath Ocean Front Vacation Rental on Edisto Beach
Ibis Cottage Suite 3717-B- part of Eden at Gracefield Event Venue
Property grounds

Ibis Cottage Suite 3717-B- part of Eden at Gracefield Event Venue

2.0 star property
10.0 out of 10, Exceptional, (6)
"beautiful location and the unit was great"
The price is ￥29,259
￥40,345 total
includes taxes & fees
Aug 31 - Sep 1
Ibis Cottage Suite 3717-B- part of Eden at Gracefield Event Venue
Coastal townhome with riverfront views, deck, & W/D - pool and athletic courts
Outdoor dining

Coastal townhome with riverfront views, deck, & W/D - pool and athletic courts

8.4 out of 10, Very Good, (20)
"Great place for families. Lots to do and see."
Coastal townhome with riverfront views, deck, & W/D - pool and athletic courts
Oceanfront 1 Bedroom-Downstairs Apartment
Terrace/patio

Oceanfront 1 Bedroom-Downstairs Apartment

9.8 out of 10, Exceptional, (79)
"The place was clean and just steps from the ocean! Great for two adults and great location. Definitely a do-over! "
Oceanfront 1 Bedroom-Downstairs Apartment
Just Renovated! Welcome to I-Land Style 4BR, 2BTH OCEANFRONT on Edisto Beach
Interior

Just Renovated! Welcome to I-Land Style 4BR, 2BTH OCEANFRONT on Edisto Beach

9.8 out of 10, Exceptional, (37)
"Beautiful beach house with great location right on the beach!"
Just Renovated! Welcome to I-Land Style 4BR, 2BTH OCEANFRONT on Edisto Beach
Cottage: 3005 Palmetto Blvd.
Exterior detail

Cottage: 3005 Palmetto Blvd.

8.4 out of 10, Very Good, (103)
"Needed a break and our stay was carefree. House totally suited us. Love the paneling."
Cottage: 3005 Palmetto Blvd.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Colleton County Hotel Reviews

Find out more about Colleton County

Find out more about Colleton County

Vacation Apartments in Colleton County

Search for Vacation rentals in Colleton County on Expedia! You can easily find your home rentals, villas, Vacation apartments in Colleton County using one of the methods below:

  • View our selection of featured Vacation rentals in Colleton County
  • Use the map to find apartments and other Vacation homes in the Colleton County neighbourhood you prefer
  • Enter your travel dates to view the best deals on Vacation rentals in Colleton County while they last

Look no further and take a look at our great range of rental properties in Colleton County!