Depew Vacation Rentals

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Vacation Rentals in Depew

PTR | Charming Apt - N Buffalo near Falls & Parks!

2.0 star property
10.0 out of 10, Exceptional, (2)
"Comfortable bed, well appointed kitchen. Great location"
PTR | Charming Apt - N Buffalo near Falls & Parks!

Three bedroom apartment in Buffalo & Niagara region 🌊

8.6 out of 10, Excellent, (14)
"We had a great time "
The price is ¥25,832
¥49,982 total
includes taxes & fees
Sep 25 - Sep 26
Three bedroom apartment in Buffalo & Niagara region 🌊

Sleeps 8 , 6 minutes sabers stadium 15 min to Niagara Falls 20 bills stadium

2.0 star property
6.0 out of 10, (2)
"We didn’t stay there were people already there staying and living I will never book again!!"
The price is ¥19,927
¥53,775 total
includes taxes & fees
Sep 26 - Sep 27
Sleeps 8 , 6 minutes sabers stadium 15 min to Niagara Falls 20 bills stadium

420 Friendly 3 bedroom upstairs apartment. Street parking. Covered porch

9.4 out of 10, Exceptional, (57)
"It all was a lovely place. The deck was really a great place to relax. Had most things you could want, the couches and beds were comfortable. The neighborhood was very nice and walkable."
The price is ¥14,023
¥20,949 total
includes taxes & fees
Oct 9 - Oct 10
420 Friendly 3 bedroom upstairs apartment. Street parking. Covered porch

Private Buffalo Suburban Family Home Near Niagara Falls

7.8 out of 10, Good, (10)
"This house was worth every penny. We got everything we needed, it was clean and was able to accommodate everyone in my family."
The price is ¥22,451
¥54,121 total
includes taxes & fees
Oct 7 - Oct 8
Private Buffalo Suburban Family Home Near Niagara Falls

Vaulted Loft in Historic Bank on Hertel King Bed + walk to shops

8.6 out of 10, Excellent, (9)
"Loved staying here! Very convenient and so clean! "
The price is ¥17,005
¥28,737 total
includes taxes & fees
Sep 30 - Oct 1
Vaulted Loft in Historic Bank on Hertel King Bed + walk to shops

Soothing 2-bedroom apartment in Buffalo

9.6 out of 10, Exceptional, (5)
The price is ¥29,522
¥52,785 total
includes taxes & fees
Sep 25 - Sep 26
Soothing 2-bedroom apartment in Buffalo

The L's Luxury 4 -Spacious 4-bedroom house with AC, fitness room in WEST Buffalo

2.0 star property
6.6 out of 10, (9)
"Property was not as advertised. The house was a little dated but it did have fresh paint and new floors and also new appliances. The porch steps were a little rickety and both doors had at least an inch of space under them."
The L's Luxury 4 -Spacious 4-bedroom house with AC, fitness room in WEST Buffalo

Right On the Niagara River - River Access Dock - Pool - Hot Tub - Firepit...more

10.0 out of 10, Exceptional, (163)
"I could not ask for a better place to stay. Our family had a very restful and relaxing trip. Property had everything we needed and more. "
Right On the Niagara River - River Access Dock - Pool - Hot Tub - Firepit...more

Tiny Spa Cottage Retreat

9.8 out of 10, Exceptional, (103)
"My favorite part was the loft bedroom. The outside of the property is very unassuming. Then you walk into this adorable space. "
The price is ¥15,942
¥27,712 total
includes taxes & fees
Sep 25 - Sep 26
Tiny Spa Cottage Retreat

The L's Luxury 2- The Tacoma Upper

2.0 star property
6.4 out of 10, (9)
"Everything was perfect! "
The L's Luxury 2- The Tacoma Upper

King bed - Perfect Room - shared living room - Bills Stadium and Tesla

The price is ¥8,635
¥23,672 total
includes taxes & fees
Sep 25 - Sep 26
King bed - Perfect Room - shared living room - Bills Stadium and Tesla

Visit Buffalo & Niagara from this Quaint Apartment

9.4 out of 10, Exceptional, (81)
"Info was correct close to shopping"
The price is ¥13,152
¥38,944 total
includes taxes & fees
Sep 25 - Sep 26
Visit Buffalo & Niagara from this Quaint Apartment

Cozy 3-bedroom house in charming Buffalo with WiFi, AC

2.0 star property
8.6 out of 10, Excellent, (9)
"The place was just as pictured and described. It was a comfortable stay close to lots of things in Buffalo. "
The price is ¥19,263
¥33,075 total
includes taxes & fees
Sep 25 - Sep 26
Cozy 3-bedroom house in charming Buffalo with WiFi, AC

Charming 4-bedroom house with AC in Orchard Park - hometown of the Buffalo Bills

10.0 out of 10, Exceptional, (6)
The price is ¥46,497
¥77,033 total
includes taxes & fees
Sep 25 - Sep 26
Charming 4-bedroom house with AC in Orchard Park - hometown of the Buffalo Bills

Dog-friendly Home ~ 14 Mi to Highmark Stadium

3.0 star property
Dog-friendly Home ~ 14 Mi to Highmark Stadium

Delightful dwelling

10.0 out of 10, Exceptional, (1)
"Perfect location for my needs . Fairly crazy access to major highways Owner included pics of the outside of the property and provided a personalized access code that was easy to remember First time I’d experienced that on Vrbo. Showed he’s on top of his rental "
The price is ¥23,839
¥49,405 total
includes taxes & fees
Oct 8 - Oct 9
Delightful dwelling

New- Downtown Condo-Canalside/Riverworks/Bills/Sabres

9.2 out of 10, Wonderful, (21)
"Overall great property and the owners were great about communicating. Area is a little sketchy but you are staying in the city. The condo was clean and close to everything we were doing. The amenities provided were great and the beds were comfortable. "
New- Downtown Condo-Canalside/Riverworks/Bills/Sabres

Just walk to the Upper Niagara River and follow it right to Niagara Falls!!!

7.8 out of 10, Good, (56)
"We loved our stay here. We went out in multiple directions to visit nearby sites and had great days. The home is clean and inviting. We would stay here again for a visit to the falls and area."
Just walk to the Upper Niagara River and follow it right to Niagara Falls!!!

228 BEAUTIFUL DOWNTOWN AIR/WIFI/close to FALLS

9.2 out of 10, Wonderful, (42)
"We had a nice stay. The house was the perfect size for us. It was clean and close to everything."
228 BEAUTIFUL DOWNTOWN AIR/WIFI/close to FALLS
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Depew Hotel Reviews

Find out more about Depew

Find out more about Depew

Search for holiday rentals in Depew on Expedia! You can easily find your home rentals, villas, holiday apartments in Depew using one of the methods below:

  • View our selection of featured holiday rentals in Depew
  • Use the map to find apartments and other holiday homes in the Depew neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Depew while they last

Look no further and take a look at our great range of rental properties in Depew!

Frequently asked questions

Can I find vacation rentals in Depew?

Yes, we have vacation rentals near well known sights in Depew, or you can choose a secluded option if you're looking for relaxation. Depew is known for its shopping and restaurants. Make sure you have time to check out the sporting events and waterfalls during your trip.

What are some of the best vacation home rentals in Depew?

Private Buffalo Suburban Family Home Near Niagara Falls: Visitors like this Depew vacation home rental. It offers a patio, a garden, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family.

How many vacation rentals will I find in Depew?

Choose from 4 Expedia vacation rentals in Depew for a memorable vacation.

What can I see and do in Depew?

While exploring the area, visit family-friendly sights like Buffalo Museum of Science, or get outside and enjoy nature at Glen Falls. Walden Galleria Mall and Samuel’s Grande Manor are a couple of places you'll find in the larger area.

What are vacation rentals like in Depew?

Vacation rentals are private accommodations you can reserve for several days or more in Depew. Vacation rentals feature extras like WiFi and washers and dryers so you'll have everything you want. If you're concerned about a sanitized environment, a vacation rental can provide a sense of safety away from shared hotel elevators and busy lobbies while still allowing you a great travel experience. You'll also find more space in a vacation rental than in a standard hotel, which makes a vacation rental a great option for a family trip.