Photo by Kate Dolan

Find hotels near Botanical Building, San Diego from ￥18,797

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 23 - Dec 24
Tomorrow
Dec 24 - Dec 25
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Botanical Building hotels

Exterior
Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
1.7 km from Botanical Building
9.4 out of 10, Exceptional, (1010)
"Room was spacious! Best hotel I’ve ever been to! "
United States
Liyah
The price is ￥21,182
￥24,559 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Marriott Vacation Club®, San Diego
Memory foam beds, blackout drapes, iron/ironing board, free WiFi
Stay Classy Hostel

Stay Classy Hostel

Stay Classy Hostel
2.0 star property
East Village, 2.3 km from Botanical Building
9.6 out of 10, Exceptional, (786)
"Good place to stay "
United States
sai
Stay Classy Hostel
Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio
City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
2.2 km from Botanical Building
9.6 out of 10, Exceptional, (107)
"would definitely go back and stay there again "
United States
Kounwick
City24 Hotel Little Italy Mission Hills
Premium bedding, pillowtop beds, desk, laptop workspace
Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 2.5 km from Botanical Building
9.4 out of 10, Exceptional, (1006)
"Great location "
United States
Mohammad
The price is ￥12,302
￥18,797 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Staypineapple, Hotel Z, Gaslamp San Diego
3 bars/lounges, lobby lounge, cocktail bar, cocktail bar
Lafayette Hotel & Club

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
2.7 km from Botanical Building
9.4 out of 10, Exceptional, (1348)
"Enjoyable an"
United States
Barry
The price is ￥35,930
￥41,229 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Lafayette Hotel & Club
Front of property
Granger Hotel Gaslamp Quarter, A Member Of Design Hotels

Granger Hotel Gaslamp Quarter, A Member Of Design Hotels

Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
4.0 star property
Gaslamp Quarter, 2.1 km from Botanical Building
9.2 out of 10, Wonderful, (628)
"Great stay"
United States
Angelica
The price is ￥24,947
￥28,924 total
includes taxes & fees
Dec 24 - Dec 25
Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
Bar (on property)
TownePlace Suites by Marriott San Diego Downtown

TownePlace Suites by Marriott San Diego Downtown

TownePlace Suites by Marriott San Diego Downtown
3.0 star property
1.5 km from Botanical Building
9.0 out of 10, Wonderful, (1010)
"Good breakfast, clean and comfortable rooms and attentive, pleasant staff, all at a great value."
United States
charles
The price is ￥19,404
￥22,498 total
includes taxes & fees
Jan 18 - Jan 19, 2026
TownePlace Suites by Marriott San Diego Downtown
View from room
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy
4.0 star property
Little Italy, 1.8 km from Botanical Building
9.0 out of 10, Wonderful, (132)
"Great place to stay "
United States
Jacorey
The price is ￥20,650
￥23,942 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Courtyard by Marriott San Diego Downtown Little Italy
Rooftop terrace
Sentral Gaslamp Quarter

Sentral Gaslamp Quarter

Sentral Gaslamp Quarter
4.0 star property
East Village, 2.4 km from Botanical Building
9.2 out of 10, Wonderful, (606)
"Everything was splendid. Very friendly staff as well. "
United States
Irving
The price is ￥17,204
￥24,494 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Sentral Gaslamp Quarter
Interior
Gaslamp Hostel

Gaslamp Hostel

Gaslamp Hostel
2.0 star property
Gaslamp Quarter, 2.3 km from Botanical Building
9.2 out of 10, Wonderful, (539)
"Great location with clean, comfortable rooms. Amazing ambiance and professional staff. I would stay hear again."
United States
Anthony Michael
Gaslamp Hostel
Restaurant
Springhill Suites San Diego Downtown/Bayfront

Springhill Suites San Diego Downtown/Bayfront

Springhill Suites San Diego Downtown/Bayfront
3.5 star property
2.6 km from Botanical Building
9.2 out of 10, Wonderful, (1008)
"Great place to stay"
United States
Kimberly
The price is ￥30,909
￥35,907 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Springhill Suites San Diego Downtown/Bayfront
Lobby
Best Western Plus Bayside Inn

Best Western Plus Bayside Inn

Best Western Plus Bayside Inn
3.0 star property
2.2 km from Botanical Building
9.0 out of 10, Wonderful, (1004)
"Great area, staff was attentive and the balcony was an unexpected surprise! Great hotel! "
United States
Armando
The price is ￥19,944
￥23,085 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Best Western Plus Bayside Inn
Standard Room, 1 King Bed, Non Smoking, Bay View | Premium bedding, pillowtop beds, in-room safe, desk
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
1.7 km from Botanical Building
8.8 out of 10, Excellent, (780)
"would stay again and recommend "
United States
Brendi
The price is ￥17,573
￥20,374 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The DEXTRO Little Italy, BW Premier Collection
Lobby
Gaslamp Plaza Suites

Gaslamp Plaza Suites

Gaslamp Plaza Suites
3.5 star property
Gaslamp Quarter, 2.1 km from Botanical Building
9.0 out of 10, Wonderful, (1018)
"Yes everything was great I will stay there again."
United States
Sergio
The price is ￥18,514
￥21,059 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Gaslamp Plaza Suites
Lobby lounge
Moxy San Diego Downtown/Gaslamp Quarter

Moxy San Diego Downtown/Gaslamp Quarter

Moxy San Diego Downtown/Gaslamp Quarter
3.5 star property
Gaslamp Quarter, 2.2 km from Botanical Building
9.0 out of 10, Wonderful, (1008)
"The staff was amazing, friendly, helpful and attentive. "
United States
Jan
The price is ￥17,811
￥22,064 total
includes taxes & fees
Dec 25 - Dec 26
Moxy San Diego Downtown/Gaslamp Quarter
Presidential Suite, 2 Bedrooms | Living room | 36-inch LCD TV with digital channels, TV, pay movies
Alma San Diego Downtown, a Tribute Portfolio Hotel

Alma San Diego Downtown, a Tribute Portfolio Hotel

Alma San Diego Downtown, a Tribute Portfolio Hotel
4.0 star property
2 km from Botanical Building
9.0 out of 10, Wonderful, (876)
"Friendly staff throughout stay and clean rooms"
United States
Alvin
The price is ￥16,946
￥26,014 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Alma San Diego Downtown, a Tribute Portfolio Hotel
Classic Studio | In-room dining
The Artifact Hotel

The Artifact Hotel

The Artifact Hotel
2.0 star property
East Village, 2.2 km from Botanical Building
9.2 out of 10, Wonderful, (45)
"Room was great, the hosts were fantastic and communicative. Absolutely will plan to stay here again in the future! "
United States
Aulani
The price is ￥15,564
￥38,089 total
includes taxes & fees
Dec 28 - Dec 29
The Artifact Hotel
2 outdoor pools, open 6 AM to 10:00 PM, cabanas (surcharge)
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
Marina District, 2.9 km from Botanical Building
9.2 out of 10, Wonderful, (1959)
"Amazing hotel Superb view Friendly staff Clean and neat rooms "
United States
Chirag
The price is ￥26,683
￥39,230 total
includes taxes & fees
Dec 25 - Dec 26
Marriott Marquis San Diego Marina
Dinner served
Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark
4.0 star property
Gaslamp Quarter, 2.8 km from Botanical Building
9.2 out of 10, Wonderful, (2051)
"Very comfortable, nice location and good service "
United States
ALEXANDER
The price is ￥30,542
￥42,508 total
includes taxes & fees
Dec 24 - Dec 25
Omni San Diego Hotel at the Ballpark
3 restaurants, breakfast, lunch, dinner served; seafood
Pendry San Diego

Pendry San Diego

Pendry San Diego
5.0 star property
Gaslamp Quarter, 2.6 km from Botanical Building
9.2 out of 10, Wonderful, (1002)
"Excellent Stay at Pendry - will definitely return when visiting San Diego"
Canada
Bobbi Jo
The price is ￥43,148
￥58,273 total
includes taxes & fees
Jan 15 - Jan 16, 2026
Pendry San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Botanical Building Hotel Reviews

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

10/10 Excellent
"Great "
jose 1-night trip
Posted 2 days ago
Hard Rock Hotel San Diego

Hotels near other Botanical Building attractions

Timken Museum of Art which includes art

Timken Museum of Art

View a priceless collection of masterpieces from Europe, the U.S. and Russia in this gorgeous community museum, known as San Diego’s jewel box of art.
See properties
Amazing architecture
Photo by Taozi
Open Photo by Taozi

San Diego Model Railroad Museum

You can spend time studying the exhibits at San Diego Model Railroad Museum in San Diego. Stroll along the area's beautiful beaches or experience its acclaimed art scene.
See properties

Frequently asked questions

What's the area like around Botanical Building?
Botanical Building is located in an area of San Diego known for its beautiful ocean views, array of dining options, and bird watching. If you're looking for a convenient place to stay, check out the 119 hotels and other accommodations you'll find within a mile.
Where is the best place to stay near Botanical Building?
Holiday Inn Express San Diego Downtown by IHG is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a restaurant. It's located just a short 1 mi (1.5 km) from Botanical Building. Other good choices within 5 miles include The DEXTRO Little Italy, BW Premier Collection and Courtyard by Marriott San Diego Downtown Little Italy.
How many hotels should I expect to find near Botanical Building?
Expedia has 119 hotels and other accommodations within a mile from Botanical Building.
If I need to cancel the hotel reservation for my stay near Botanical Building, will I receive a refund?
Yes, most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the best deals available near Botanical Building.
Where can I learn more about changing or cancelling my trip in the area near Botanical Building?
To access more information about picking new dates or cancelling your stay near Botanical Building, click here.
What can I see and do near Botanical Building?
San Diego Museum of Art, San Diego Natural History Museum, and San Diego Air and Space Museum feature captivating exhibits. Hotel del Coronado, Casa de Balboa, and California Tower are notable landmarks to explore if you're in the area. You can catch a show at Old Globe Theater, San Diego Civic Theatre, and The Rady Shell at Jacobs Park.