A wooden bench in a forest with a natural backdrop of trees and foliage.

Find 4 Star Hotels in Southeastern Indiana from ￥20,996

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southeastern Indiana 4 Star Hotels

Tonight
Oct 14 - Oct 15
Tomorrow
Oct 15 - Oct 16
This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

Our top choices for Southeastern Indiana 4-star hotels

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
A balcony with a view of a river, a bridge, and a cityscape.
A spacious room with a large dining table, comfortable seating, a sofa, and a view of a bridge.
A modern bar with a long counter, multiple shelves of liquor bottles, and cushioned bar stools.

1. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
United States
Mark
￥22,944
￥26,995 total
includes taxes & fees
Oct 27 - Oct 28
Galt House Hotel Trademark Collection by Wyndham
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.
A modern interior with a fireplace, bookshelves, and seating areas.
A lobby with a marble floor, a reception desk, and a large chandelier.

2. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville
United States
Samantha
￥19,857
￥23,364 total
includes taxes & fees
Oct 18 - Oct 19
Omni Louisville Hotel
A grand lobby with ornate columns, plush seating, and a chandelier.
A grand lobby with ornate ceiling and chandeliers, a large vase, and a seating area with multiple sofas and armchairs.
A grand dining area with ornate ceiling, chandeliers, and a bar area with a sign reading "Cigar Bar".
A grand lobby with ornate ceiling, large windows, and classic furniture.

3. The Brown Hotel

The Brown Hotel
Downtown Louisville
United States
John
￥19,808
￥23,307 total
includes taxes & fees
Oct 29 - Oct 30
The Brown Hotel
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.
A modern hotel room with a living area, a dining area, and a bedroom.
An indoor swimming pool with clear water, surrounded by white marble walls and columns, and furnished with lounge chairs and tables.
A modern bar area with a long counter, multiple chairs, and a bookshelf filled with bottles.

4. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
Downtown Louisville
United States
Frances
￥20,610
￥24,249 total
includes taxes & fees
Nov 15 - Nov 16
Embassy Suites Louisville Downtown
A modern lobby with a curved metallic structure, a seating area with a sofa and a small table, and an escalator in the background.
A modern indoor swimming pool with clear glass walls, lounge chairs, and a wooden wall in the background.
A reception area with a wooden wall and a neon sign that reads "Sway LOCAL SOUTHERN EATERY".
A bar area with wooden paneling, multiple seating arrangements, and a variety of liquor bottles displayed on shelves.

5. Hyatt Regency Louisville

Hyatt Regency Louisville
Downtown Louisville
United States
Lester
￥26,083
￥30,691 total
includes taxes & fees
Oct 29 - Oct 30
Hyatt Regency Louisville
A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.
A modern bar area with glass partitions, bar stools, and a variety of bottles.
A spacious lobby with a bar area, seating arrangements, and a visible kitchen bar.
A modern hotel room with a large window offering a city view, a cozy seating area with a sofa and chairs, a dining table with lamps, and a wooden floor.

6. Louisville Marriott Downtown

Louisville Marriott Downtown
Downtown Louisville
United States
Veronica
￥21,756
￥25,597 total
includes taxes & fees
Nov 13 - Nov 14
Louisville Marriott Downtown
A classical gold statue in front of a multi-story building with large windows and a brick facade.
A restaurant with multiple dining tables, a long bench seating area, and framed artwork on the walls.
A steam fountain in a brick alleyway.
A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.

7. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville
United States
Matt
￥24,090
￥29,137 total
includes taxes & fees
Nov 8 - Nov 9
21c Museum Hotel Louisville
A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.
A yellow coffee shop counter with a menu board above, displaying various coffee and food items.
A bar area with a wooden bar counter, two stools, a chandelier, and a mirror.
A brightly lit grocery store with yellow shelving and a central checkout counter.

8. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
Downtown Louisville
United States
Tyler
￥21,376
￥25,151 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Genevieve part of JdV by Hyatt
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
An outdoor dining area with tables and chairs, a green building facade, and a row of plants along the wall.
A bar with shelves of liquor bottles and a bartender preparing drinks.
A modern living room with a leather sectional sofa, a glass coffee table, and a view of the city skyline through large windows.

9. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
Downtown Louisville
United States
Heather
￥37,421
￥44,029 total
includes taxes & fees
Oct 29 - Oct 30
Hotel Distil, Autograph Collection
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
A multi-level interior with a staircase, bookshelves, and a prominent sign reading "THE GRADY".
A building with a sign reading "THE GRADY" at the entrance.
A modern hotel room with a large bed, a desk with a flat-screen TV, a green armchair, and a view of the city through large windows.

10. The Grady

The Grady
Downtown Louisville
United States
Donna
￥24,621
￥28,970 total
includes taxes & fees
Nov 15 - Nov 16
The Grady
An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.
A modern lobby with a central reception desk, seating area, and a large abstract wall art piece.
A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.
A modern living room with a sofa, a coffee table, a side table with a plant, and a view of a building with a clock tower.

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Downtown Louisville
United States
Cameron
￥28,388
￥33,402 total
includes taxes & fees
Oct 25 - Oct 26
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A historic hotel with ornate architecture, a grand entrance, and a red carpet leading to the doors.
A bakery display with pastries and bread, a coffee station, and a Christmas tree in the background.
A spacious living room with a fireplace, wooden paneling, a television, and a blue sofa.
A grand lobby with marble floors, a staircase, and a reception desk.

12. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
Downtown Louisville
United States
Colleen
￥26,033
￥30,631 total
includes taxes & fees
Oct 29 - Oct 30
Seelbach Hilton Louisville Downtown
A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.
A modern KFC building with large glass windows, a prominent sign, and a well-lit entrance area.
A modern bedroom with a bed, a blue sofa, a large rug, and a TV on the wall.
A modern interior with a green wall, black chairs, and a ceiling with exposed beams and lights.

13. Stellar Suites

Stellar Suites
Downtown Louisville
United States
Kevin
￥18,281
￥29,476 total
includes taxes & fees
Oct 18 - Oct 19
Stellar Suites
A grand entrance with a staircase leading to a door, flanked by two lamp posts and a bench.
A long table set with white tablecloths, gold chargers, and clear glassware.
A marble countertop with a tray of colorful glassware, a bottle, and two glasses. A framed painting hangs above, and two lamps are on either side.
A covered porch with a brick wall, a wooden door, and a hanging light fixture.

14. The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
New Albany
United States
David
￥18,580
￥20,996 total
includes taxes & fees
Oct 29 - Oct 30
The Pepin Mansion Historic B&B
A modern lounge with leather sofas, a coffee table, and a view of a classical building.
A modern interior with a wooden dining table, leather sofas, and a bar area with shelves.
A building with a sign reading "Pursuit Spirits Co." and a large window display.
A modern living room with a leather sofa, two coffee tables, and a chessboard. There are shelves with bottles and glasses, and a large window on the right.

15. The Reserve on Main

The Reserve on Main
Downtown Louisville
United States
De'Carlon
The Reserve on Main
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a high-rise building with balconies.
A modern kitchen with white cabinets, stainless steel appliances, and a dining area with a table and chairs.
A multi-story residential building with balconies, a brick facade, and large windows.
A modern living room with a dining area, a blue sofa, a ceiling fan, and a view of a balcony.

16. CozySuites at Nulu

CozySuites at Nulu
Downtown Louisville
United States
Jennifer
￥14,860
￥35,598 total
includes taxes & fees
Oct 18 - Oct 19
CozySuites at Nulu
A modern hotel with a 'Stay Apt Suites' sign, featuring a brick facade, large windows, and a parking lot.
A reception desk with a dark wood finish, a sign reading "stay apt SUITES", and a telephone.
Private kitchen
In-room dining

17. stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
Clarksville
Canada
Darlene
￥25,176
￥28,449 total
includes taxes & fees
Oct 17 - Oct 18
stayAPT Suites Louisville North-Clarksville
A large, multi-story building with a prominent tower and multiple windows.
A large outdoor swimming pool with a Ferris wheel in the background.
A dining table set with placemats, folded napkins, cutlery, and a coffee cup.
A cozy seating area with two leather armchairs and a small round table. A table lamp and a wine glass are on the table.

18. Bourbon Barrel Inn Bed & Breakfast

Bourbon Barrel Inn Bed & Breakfast
Old Louisville
United States
jonathan
Bourbon Barrel Inn Bed & Breakfast
A modern kitchen with wooden cabinets, a black microwave, and a stainless steel refrigerator.
A kitchen with a black refrigerator, a dining area with a table and chairs, and a living room with a blue sofa.
A living room with a sofa, a coffee table, and a ceiling fan. There is a dining area with a table and chairs.
A two-story brick house with a garage, a front door, and a small front yard with a lawn and a few shrubs.

19. Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
Sellersburg
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
A grand hotel with a prominent tower, multiple staircases, and a well-lit entrance.
A large, historic building with multiple towers and a central dome, surrounded by lush greenery.
A grand hotel lobby with a high ceiling, large windows, and a central courtyard with seating areas.
A large, multi-level atrium with a central circular area, surrounded by multiple floors of rooms with balconies.

20. West Baden Springs Hotel

West Baden Springs Hotel
West Baden Springs
United States
Anonymous traveler
West Baden Springs Hotel
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Southeastern Indiana

Live music, a scenic riverfront, and sights from Deam Lake State Recreation Area to Huber’s Orchard, Winery & Vineyards—discover it all in Southeastern Indiana.

See all hotels in Southeastern Indiana
A riverboat with multiple decks and passengers, docked near a bridge.

Top Southeastern Indiana Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Southeastern Indiana?
You'll find an array of 4-star hotels in Southeastern Indiana, including in Louisville. Galt House Hotel Trademark Collection by Wyndham is a guest favorite in this city that offers concierge services and massage services. Another property that gets excellent reviews from travelers is Hyatt Regency Louisville. A swimming pool and concierge services help make it a top choice.
How much does it cost to stay in a 4-star hotel in Southeastern Indiana?
Expedia can help you easily track down the ideal 4-star hotel for your vacation in Southeastern Indiana. Use our filter tool to fine-tune your search by things like price, amenities and hotel star rating and get access to fantastic deals in a few clicks.
  • Search for the lowest price from ￥20,996
What's the difference between 5-star and 4-star hotels in Southeastern Indiana?
If you decide to book a stay at a 4-star hotel in Southeastern Indiana, you'll usually find plenty of conveniences to make sure you're relaxed, such as a gym, restaurant and pool. You can look forward to excellent service and upmarket surroundings. Choose a 5-star hotel and you'll have access to a few more perks — think on-site spas, around-the-clock concierge and indulgent turndown services. You're likely to get additional amenities and first-rate services at a 5-star stay, but both are terrific options for luxury guests.

Explore a world of travel with Expedia