Find 4 Star Hotels in Lyon City Centre from ￥12,326

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Check prices for these dates

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Nov 5 - Nov 6
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Nov 6 - Nov 7
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Nov 6 - Nov 8
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Nov 13 - Nov 15

Our top choices for Lyon City Centre 4-star hotels

A modern dining area with large windows offering a city view, multiple tables and chairs, and a contemporary chandelier.

1. Radisson Blu Hotel Lyon

Radisson Blu Hotel Lyon
4.0 star property
Lyon City Centre
8.2 out of 10, Very good, (1,002 reviews)
"Good hotel."
United States
Jiasong
The price is ￥19,733
￥22,725 total
includes taxes & fees
Nov 15 - Nov 16
Radisson Blu Hotel Lyon
Business center

2. Mercure Lyon Centre Saxe Lafayette

Mercure Lyon Centre Saxe Lafayette
4.0 star property
Lyon City Centre
8.8 out of 10, Excellent, (1,002 reviews)
"It was a nice and clean hotel in a great location."
United States
Trudy
The price is ￥16,498
￥19,165 total
includes taxes & fees
Nov 15 - Nov 16
Mercure Lyon Centre Saxe Lafayette
Miscellaneous

3. Mercure Lyon Centre Château Perrache

Mercure Lyon Centre Château Perrache
4.0 star property
Lyon City Centre
8.2 out of 10, Very good, (937 reviews)
"Nice large rooms ! Well located !"
Canada
Trudy
The price is ￥13,748
￥16,141 total
includes taxes & fees
Nov 15 - Nov 16
Mercure Lyon Centre Château Perrache
A modern restaurant with wicker furniture, hanging pendant lights, and a kitchen area visible in the background.

4. Bikube Coliving Hôtel - Lyon Centre Lumière

Bikube Coliving Hôtel - Lyon Centre Lumière
4.0 star property
Lyon City Centre
9.0 out of 10, Wonderful, (408 reviews)
"Very nice place to stay."
Canada
Kelly Ann
The price is ￥12,387
￥14,644 total
includes taxes & fees
Nov 20 - Nov 21
Bikube Coliving Hôtel - Lyon Centre Lumière
An indoor swimming pool with stone walls and a wooden structure in the background.

5. Grand Hotel Des Terreaux

Grand Hotel Des Terreaux
4.0 star property
Lyon City Centre
8.8 out of 10, Excellent, (1,002 reviews)
"Brilliant location and wonderful staff."
Australia
Peter
The price is ￥16,110
￥18,739 total
includes taxes & fees
Nov 8 - Nov 9
Grand Hotel Des Terreaux
A modern bathroom with a large bathtub, a shower area, and wooden steps leading to a seating area.

6. Keystone Hotel & Spa Lyon - Handwritten Collection

Keystone Hotel & Spa Lyon - Handwritten Collection
4.0 star property
Lyon City Centre
9.0 out of 10, Wonderful, (410 reviews)
"We enjoyed everything about this hotel. The staff was very helpful and the breakfast was great."
United States
Christine
The price is ￥16,125
￥18,756 total
includes taxes & fees
Nov 8 - Nov 9
Keystone Hotel & Spa Lyon - Handwritten Collection
An outdoor cafe with tables and chairs, umbrellas, and a building facade with windows and balconies.

7. Globe et Cecil Hôtel

Globe et Cecil Hôtel
4.0 star property
Lyon City Centre
8.6 out of 10, Excellent, (673 reviews)
"Very comfortable and location is good."
United Kingdom
Junichi
The price is ￥23,346
￥26,698 total
includes taxes & fees
Nov 9 - Nov 10
Globe et Cecil Hôtel
Exterior

8. Pullman Lyon

Pullman Lyon
4.0 star property
Lyon City Centre
9.6 out of 10, Exceptional, (702 reviews)
"Modern and tidy business hotel right next to Gare Lyon Part Dieu."
Hong Kong SAR China
Pak Ki
The price is ￥18,116
￥20,946 total
includes taxes & fees
Nov 8 - Nov 9
Pullman Lyon
A balcony with a view of a river and buildings.

9. Le Phenix Hotel

Le Phenix Hotel
4.0 star property
Lyon City Centre
9.2 out of 10, Wonderful, (1,000 reviews)
"It's a great hotel located in a beautiful part of town. We had a lovely few days there."
United Kingdom
Valerie
The price is ￥19,472
￥22,437 total
includes taxes & fees
Nov 8 - Nov 9
Le Phenix Hotel
A modern reception area with a curved desk, multiple monitors, and pendant lighting.

10. Hôtel Mercure Lyon Centre - Gare Part Dieu

Hôtel Mercure Lyon Centre - Gare Part Dieu
4.0 star property
Lyon City Centre
9.2 out of 10, Wonderful, (1,000 reviews)
"Spacious room!"
Australia
Je Kit Joel
The price is ￥15,527
￥18,098 total
includes taxes & fees
Nov 15 - Nov 16
Hôtel Mercure Lyon Centre - Gare Part Dieu
A blue building with large windows and outdoor seating.

11. Hotel Silky by HappyCulture

Hotel Silky by HappyCulture
4.0 star property
Lyon City Centre
8.8 out of 10, Excellent, (1,001 reviews)
"Really great staff, nice rooms and perfect location to explore the city."
Denmark
Christian
The price is ￥15,986
￥18,601 total
includes taxes & fees
Nov 15 - Nov 16
Hotel Silky by HappyCulture
A modern hotel reception area with a wooden reception desk, a TV screen, and a large window offering a view of the city.

12. Q7 Lodge Lyon 7

Q7 Lodge Lyon 7
4.0 star property
Lyon City Centre
8.4 out of 10, Very good, (593 reviews)
"Lovely apartment, concierge was very helpful and polite. Good size for a family of four for an overnight visit."
United States
Tara
The price is ￥11,209
￥13,348 total
includes taxes & fees
Nov 13 - Nov 14
Q7 Lodge Lyon 7
A buffet setup with multiple food containers, a counter with stools, and overhead hanging pots.

13. Mama Shelter Lyon

Mama Shelter Lyon
4.0 star property
Lyon City Centre
9.0 out of 10, Wonderful, (570 reviews)
"Fun place to stay. Not your usual cookie-cutter hotel."
United States
Lorene
The price is ￥15,042
￥17,565 total
includes taxes & fees
Nov 22 - Nov 23
Mama Shelter Lyon
A restaurant with round tables, chairs, and hanging light fixtures.

14. Novotel Lyon Centre Confluence Bord de Saone

Novotel Lyon Centre Confluence Bord de Saone
4.0 star property
Lyon City Centre
8.8 out of 10, Excellent, (982 reviews)
"Great location, friendly and professional staff, good dining options, great inroom facilities and very convenient for a family"
Spain
Charles
The price is ￥16,644
￥19,326 total
includes taxes & fees
Nov 22 - Nov 23
Novotel Lyon Centre Confluence Bord de Saone
A hotel with a modern facade, large windows, and a prominent sign.

15. Hôtel Le Roosevelt

Hôtel Le Roosevelt
4.0 star property
Lyon City Centre
9.4 out of 10, Exceptional, (293 reviews)
"Great location. Lots of restaurants and Boulanger nearby. Easy to metro, but walkable to Les Halles Paul Bocuse and other sites. The cold still and sparkling water in the lobby is a nice touch A negative is the oddly configured bathroom, at least ours was, and the lack of espresso machine in the room"
United States
Bradley
The price is ￥13,592
￥15,969 total
includes taxes & fees
Nov 8 - Nov 9
Hôtel Le Roosevelt
A breakfast buffet with various food items and a large poster on the wall.

16. Novotel Lyon Gerland

Novotel Lyon Gerland
4.0 star property
Lyon City Centre
8.2 out of 10, Very good, (1,000 reviews)
"Excellent rooms and great staff. Breakfast was amazing. Great location 10 mins drive from the old city. Highly recommended."
Canada
Tayyaba
The price is ￥14,564
￥17,039 total
includes taxes & fees
Nov 8 - Nov 9
Novotel Lyon Gerland
A historic building with multiple stories, classic architecture, and a river in the foreground.

17. Hotel Charlemagne By HappyCulture

Hotel Charlemagne By HappyCulture
4.0 star property
Lyon City Centre
8.4 out of 10, Very good, (1,002 reviews)
"Large room, friendly helpful staff, and a great breakfast."
Canada
Francis
The price is ￥13,910
￥16,319 total
includes taxes & fees
Nov 12 - Nov 13
Hotel Charlemagne By HappyCulture
A modern interior with a fireplace, seating area, and tables.

18. Best Western Plus Hotel du Pont Wilson

Best Western Plus Hotel du Pont Wilson
4.0 star property
Lyon City Centre
8.6 out of 10, Excellent, (694 reviews)
"This is a convenient location with very helpful staff."
United States
Dale
The price is ￥14,725
￥17,216 total
includes taxes & fees
Nov 13 - Nov 14
Best Western Plus Hotel du Pont Wilson
A modern dining area with a long wooden table, black bar stools, and pendant lighting.

19. OKKO Hotels Lyon Centre

OKKO Hotels Lyon Centre
4.0 star property
Lyon City Centre
9.0 out of 10, Wonderful, (1,001 reviews)
"Nice location, close to everything and the old town. Very nice and helpful staff."
United States
Pablo
The price is ￥18,763
￥21,657 total
includes taxes & fees
Nov 15 - Nov 16
OKKO Hotels Lyon Centre
A rooftop terrace with outdoor seating, tables, and chairs, overlooking a cityscape with historic buildings and a church.

20. Maison Nô

Maison Nô
4.0 star property
Lyon City Centre
9.2 out of 10, Wonderful, (543 reviews)
"Great location."
Canada
sean
The price is ￥12,326
￥14,577 total
includes taxes & fees
Nov 22 - Nov 23
Maison Nô

Top Lyon City Centre Hotel Reviews

Exterior
Pullman Lyon

Pullman Lyon

Pullman Lyon
Lyon City Centre

10/10 Excellent

Pullman in Lyon was ideal as were were leaving by train the next day. Turned out not just convenient, it was an excellent hotel for many other great reasons! Very hospitable and highly recommended.
United States
Gene
Reviewed October 19, 2026
Pullman Lyon

Frequently Asked Questions

What are the best 4-star hotels in Lyon City Centre?

Hôtel Alexandra is one of our customers' favorite 4-star hotels around Lyon City Centre. A terrace and free WiFi are a couple of its many conveniences. Another pick that gets top reviews for its excellent guest experience is Best Western Hotel Du Pont Wilson. Book your break here and enjoy access to room service and a separate sitting area.

How much does it cost to stay in a 4-star hotel in Lyon City Centre?

With Expedia's search and sort filters, scoring a top deal on a 4-star hotel in Lyon City Centre just got easier. Start by entering your chosen arrival date and length of your getaway. Then list the results by price and pick a property that best fits your style and budget.

  • Search for the lowest price from ￥12,326

What's the difference between 5-star and 4-star hotels in Lyon City Centre?

If you choose to vacation at a 4-star hotel in Lyon City Centre, you'll typically find plenty of amenities to keep you relaxed, such as a restaurant, gym and pool. You can look forward to top-quality service and upscale accommodations. Go for a 5-star hotel and you'll have access to a few more bells and whistles — think on-site spas, concierge assistance and opulent turndown services. You'll most likely get additional amenities and premium services at a 5-star stay, but both are awesome options for luxury travelers.

Does Lyon City Centre have any 4-star all-inclusive resorts?

Our "All inclusive" filter makes it simple to search for your dream resort. You'll also find other standard 4-star retreats such as Best Western Hotel Du Pont Wilson and Hôtel Alexandra. Offering the same level of comfort and quality, they are great options for your Lyon City Centre adventure.

Are there any 4-star casino hotels in Lyon City Centre?

Use our filter tool to refine your Lyon City Centre search by star rating, amenities and more. Whether you're craving the full gaming resort experience or simply want to wager a bet or two while living in the lap of 4-star style, you're sure to find a place that strikes the perfect balance between relaxation and entertainment.

What are the top 4-star apartments in Lyon City Centre?

Consider AppartCity Classic Lyon Part-Dieu, a top pick around Lyon City Centre with premium bedding and a dining venue. Odalys City Lyon Bioparc is another of our most popular 4-star properties here. It comes with conveniences like a garden and a terrace. Book one and enjoy vacationing in your own private pad near all the action.