Find 4 Star Hotels in Lower Keys, FL

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Check availability on Lower Keys 4 Star Hotels

Compare Lower Keys 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

3-bedroom house in Lower Keys with Hot Tub, Sleeps 10+, Pet Freindly
Outdoor spa tub

3-bedroom house in Lower Keys with Hot Tub, Sleeps 10+, Pet Freindly

4.0 star property
3-bedroom house in Lower Keys with Hot Tub, Sleeps 10+, Pet Freindly
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Learn more about Lower Keys

Explore the relaxing area of Lower Keys—parks, boating, and sights from Florida Keys Beaches to Sugarloaf Beach.

See all hotels in Lower Keys
Big Pine Key featuring a river or creek, a bay or harbor and general coastal views

Top Lower Keys Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Lower Keys?
Little Palm Island Resort & Spa - A Noble House Resort is highly recommended by many Expedia customers. Situated in Summerland Key, Lower Keys, this 4-star hotel features loads of amenities to help make your stay more comfortable.
How much does it cost to stay in a 4-star hotel in Lower Keys?
With Expedia's sort and search filters, locking in a superb deal on a 4-star hotel in Lower Keys just got easier. Start by entering your chosen arrival date and length of your break. Then sort the results by price and pick a hotel that best matches your style and budget.

  • Search for the lowest price

What's the difference between 5-star and 4-star hotels in Lower Keys?
Give yourself the luxury treatment during your Lower Keys vacation by checking in to a 4-star hotel. As well as featuring upmarket accommodations, these properties are typically packed with amenities like complimentary bathrobes, large beds and plenty more. A 5-star hotel will go above and beyond to make your stay an even more indulgent and special one. Concierge assistance, elegant décor and gourmet dining are only the start of the superior conveniences and services you'll likely have access to.