A calm sea with a small boat and a row of palm trees on the shore.

Find 4 Star Hotels in Eastern Panama from ￥73,423

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Check availability on Eastern Panama 4 Star Hotels

Tonight
Sep 22 - Sep 23
Tomorrow
Sep 23 - Sep 24
This weekend
Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4

Our top choices for Eastern Panama 4-star hotels

Pearl of the Sea | Beach/ocean view
Owner's Suite King Size | Bathroom | Shower, rainfall showerhead, free toiletries, hair dryer
Property grounds
Outdoor pool

1. Ordovician Beach Resort

Ordovician Beach Resort
Isla Grande
Canada
Janet
￥66,561
￥73,423 total
includes taxes & fees
Sep 23 - Sep 24
Ordovician Beach Resort
Room, Mountain View, Mountainside | WiFi (free)
Exterior
Room, Mountain View, Mountainside | Bathroom
Basic Suite, Mountain View | WiFi (free)

2. Mandalas Ecolodge

Mandalas Ecolodge
Caimitillo
Mandalas Ecolodge
Outdoor pool
Exterior
Sun Villa (with Kitchenette) | In-room safe, desk, blackout drapes, WiFi (free)
Sun Villa (with Kitchenette) | In-room safe, desk, blackout drapes, WiFi (free)

3. El Otro Lado

El Otro Lado
Portobelo
United States
Jacob
El Otro Lado
Premier Apartment, Bay View | Premium bedding, down comforters, desk, laptop workspace
Premium bedding, down comforters, desk, laptop workspace
30-inch TV with premium channels, DVD player
Premier Apartment, Bay View | Bathroom | Shower, designer toiletries, towels, soap

4. Portobello Historico

Portobello Historico
Portobelo
Portobello Historico
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Learn more about Eastern Panama

Explore attractions like Cayos Holandeses and Chagres National Park as you discover things to see and do in Eastern Panama.

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A small island with palm trees surrounded by clear blue waters.
Photo by Discover Near and Far

Top Eastern Panama Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Eastern Panama?
With Expedia's handy filter tool, scoring an awesome deal on a 4-star hotel in Eastern Panama just got simpler. Start by keying in your chosen arrival date and length of your vacation. Then sort the results by price and pick the option that best matches your budget and style.
  • Search for the lowest price from ￥73,423
What's the difference between 5-star and 4-star hotels in Eastern Panama?
If you decide to book a stay at a 4-star hotel in Eastern Panama, you'll usually find lots of conveniences to keep you comfortable, such as a pool, restaurant and gym. You can experience top-quality service and upscale accommodations. Go for a 5-star hotel and you'll have access to a few more bells and whistles — think on-site spas, concierge assistance and nightly turndown services. You'll most likely get extra amenities and premium services at a 5-star retreat, but both are terrific options for luxury guests.
Does Eastern Panama have any 4-star all-inclusive resorts?
Use our "All inclusive" filter to find your next getaway in Eastern Panama where just about everything is taken care of, from your meals to your accommodations, activities and entertainment. We can also help you find standard 4-star stays in and around this leading destination.