Find 4 Star Hotels in Eastern Panama

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Check availability on Eastern Panama 4 Star Hotels

Tonight
Aug 25 - Aug 26
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Aug 26 - Aug 27
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Aug 29 - Aug 31
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Sep 5 - Sep 7

Compare Eastern Panama 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Ordovician Beach Resort
Luxury Suite | 1 bedroom, Egyptian cotton sheets, premium bedding, pillowtop beds

Ordovician Beach Resort

4.5 star property
10.0 out of 10, Exceptional, (2)
"The Ordovician Hotel is a hidden gem on the peaceful west side of Isla Grande. From the moment we booked, the service was personal and seamless—thank you, Yohan! We were welcomed by name, greeted with a delicious tropical drink, and felt like cherished guests from start to finish. We stayed in the Peacock Room, which had stunning views of the pool, restaurant, and beach. The room was beautifully curated, with luxurious bedding, high-end amenities, and thoughtful touches like a handwritten...
Ordovician Beach Resort
Mandalas Ecolodge
Exterior

Mandalas Ecolodge

4.0 star property
Mandalas Ecolodge
El Otro Lado
Outdoor pool

El Otro Lado

4.0 star property
9.8 out of 10, Exceptional, (8)
"Amazing.. Amazing. You need extra words, We loved it. We loved it.Amazing.. Amazing. You need extra words, We loved it. We loved it. Amazing.. Amazing. You need extra words, We loved it. We loved it. "
El Otro Lado
Portobello Historico
Premium bedding, down comforters, individually decorated

Portobello Historico

4.0 star property
Portobello Historico
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Learn more about Eastern Panama

Explore attractions like Cayos Holandeses and Chagres National Park as you discover things to see and do in Eastern Panama.

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Frequently asked questions

How much does it cost to stay in a 4-star hotel in Eastern Panama?
With Expedia's handy filter tool, scoring an awesome deal on a 4-star hotel in Eastern Panama just got simpler. Start by keying in your chosen arrival date and length of your vacation. Then sort the results by price and pick the option that best matches your budget and style.

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What's the difference between 5-star and 4-star hotels in Eastern Panama?
If you decide to book a stay at a 4-star hotel in Eastern Panama, you'll usually find lots of conveniences to keep you comfortable, such as a pool, restaurant and gym. You can experience top-quality service and upscale accommodations. Go for a 5-star hotel and you'll have access to a few more bells and whistles — think on-site spas, concierge assistance and nightly turndown services. You'll most likely get extra amenities and premium services at a 5-star retreat, but both are terrific options for luxury guests.
Does Eastern Panama have any 4-star all-inclusive resorts?
Use our "All inclusive" filter to find your next getaway in Eastern Panama where just about everything is taken care of, from your meals to your accommodations, activities and entertainment. We can also help you find standard 4-star stays in and around this leading destination.