An aerial view of a city with a prominent church with a large dome and spires, surrounded by various buildings and streets.

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Check availability on Tlaxcala Resorts & Hotels with Spas

Our top choices for Tlaxcala hotels with a spa

A room with a bed, a hammock, a chair, and a window with a view of trees.

1. Hotel San Francisco Tlaxcala

Hotel San Francisco Tlaxcala
3.5 star property
Tlaxcala
9.0 out of 10, Wonderful, (563 reviews)
  • cleanliness
    Urban sanctuary in Tlaxcala offers garden views, hot stone massages, and swim-up bar for relaxation.
The price is ￥11,783
￥13,904 total
includes taxes & fees
Nov 29 - Nov 30
Hotel San Francisco Tlaxcala
A hotel lobby with a reception desk, a staircase, and a check-in counter.

2. HOTEL XIADANI temazcal y SPA

HOTEL XIADANI temazcal y SPA
3.0 star property
Tlaxcala
9.0 out of 10, Wonderful, (75 reviews)
  • cleanliness
    Unwind in a tranquil sanctuary offering in-room massages and garden relaxation at this Tlaxcala hotel with soothing spa services.
The price is ￥5,586
￥6,591 total
includes taxes & fees
Nov 20 - Nov 21
HOTEL XIADANI temazcal y SPA
A room with two blue chairs, a small wooden table, a television on the wall, and a view through a glass door.

3. Holiday Inn Tlaxcala by IHG

Holiday Inn Tlaxcala by IHG
3.5 star property
Yauhquemehcan
9.6 out of 10, Exceptional, (324 reviews)
  • cleanliness
    Rejuvenate in the mountains at this hotel with hot stone massages and body treatments at its full-service spa.
The price is ￥16,189
￥19,103 total
includes taxes & fees
Dec 14 - Dec 15
Holiday Inn Tlaxcala by IHG
A modern hotel room with a bed, a glass-enclosed shower, a vanity with a mirror, and a large framed artwork on the wall.

4. Grand Fiesta Americana Puebla Angelópolis

Grand Fiesta Americana Puebla Angelópolis
5.0 star property
Angelópolis
9.8 out of 10, Exceptional, (1,006 reviews)
  • cleanliness
    Revitalize in this luxury hotel's full-service spa with sauna, steam room, and poolside relaxation in Puebla.
The price is ￥24,038
￥28,606 total
includes taxes & fees
Dec 8 - Dec 9
Grand Fiesta Americana Puebla Angelópolis
A reception area with a 'SPA' sign, wicker furniture, and a view through a glass door.

5. InterContinental Presidente Puebla by IHG

InterContinental Presidente Puebla by IHG
4.0 star property
Puebla
9.2 out of 10, Wonderful, (1,005 reviews)
  • cleanliness
    Rejuvenate at this upscale Puebla hotel where 3 treatment rooms and hot stone massages await for a therapeutic escape.
The price is ￥12,185
￥14,501 total
includes taxes & fees
Nov 29 - Nov 30
InterContinental Presidente Puebla by IHG
The entrance to a hotel with a sign reading "SARENYA HOTEL RESTAURANTE".

6. Hotel Boutique Casareyna

Hotel Boutique Casareyna
4.5 star property
Puebla Historic Center
9.6 out of 10, Exceptional, (1,003 reviews)
  • cleanliness
    Unwind in this boutique hotel's serene spa with couples treatment rooms and aromatherapy services.
The price is ￥13,217
￥15,889 total
includes taxes & fees
Dec 16 - Dec 17
Hotel Boutique Casareyna
A modern kitchen with marble countertops, wooden cabinets, and a central island.

7. Radisson Puebla Angelopolis

Radisson Puebla Angelopolis
4.5 star property
Angelópolis
9.2 out of 10, Wonderful, (692 reviews)
  • cleanliness
    Luxurious spa sanctuary offers hot stone massages and revitalizing facials in tranquil treatment rooms near Angelopolis Commercial Center.
The price is ￥10,692
￥12,724 total
includes taxes & fees
Nov 30 - Dec 1
Radisson Puebla Angelopolis
A room with a massage table, two potted plants, a textured wall, and a wooden door.

8. Hotel Azucena

Hotel Azucena
3.0 star property
Huamantla
8.0 out of 10, Very good, (156 reviews)
  • cleanliness
    Soothing spa services in a tranquil garden hotel with massage, sauna, and fitness center for relaxation.
The price is ￥6,384
￥7,533 total
includes taxes & fees
Nov 16 - Nov 17
Hotel Azucena
A grand staircase with a checkered floor leading to a balcony, surrounded by stone walls and furnished seating.

9. MILO Casa Boutique

MILO Casa Boutique
4.0 star property
Puebla Historic Center
9.6 out of 10, Exceptional, (165 reviews)
  • cleanliness
    Discover a rejuvenating spa retreat at this boutique hotel near Zócalo de Puebla with luxurious massages and a tranquil rooftop terrace.
The price is ￥13,182
￥15,687 total
includes taxes & fees
Nov 16 - Nov 17
MILO Casa Boutique
A spa room with two wooden loungers, a large bathtub, and a glass partition.

10. Cartesiano Boutique & Wellness Hotel

Cartesiano Boutique & Wellness Hotel
4.5 star property
Puebla Historic Center
9.6 out of 10, Exceptional, (931 reviews)
  • cleanliness
    Unwind in an elegant spa sanctuary with 5 treatment rooms and a serene garden oasis for total rejuvenation.
The price is ￥29,293
￥34,859 total
includes taxes & fees
Nov 16 - Nov 17
Cartesiano Boutique & Wellness Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Tlaxcala

Pool
Breakfast included

Top Tlaxcala Hotel Reviews

Quinta Real Puebla

Quinta Real Puebla

10/10 Excellent
"We truly loved our stay at Quinta Real Puebla! From the moment we arrived, we felt welcomed by the beautiful atmosphere and warm hospitality. Our room was lovely and spotless, and the restaurant was a wonderful experience—delicious food and truly exquisite service! The location is perfect for walking around and discovering Puebla’s charming streets, attractions, and restaurants. Thank you for making our visit so special and memorable. We would happily stay here again! ❤️"
Tobias 3-night trip
Posted 5 days ago
Quinta Real Puebla

Frequently asked questions

Looking to vacation at a spa hotel in Tlaxcala?
Book one of our wonderful spa hotels and treat yourself from the moment you arrive. Check out the museums and theater scene in Tlaxcala—your cultural tour starts here. Enjoy the historical sites and natural parks during your vacation. Spa hotels are the perfect way to break away from your daily routine and add a layer of luxury to your vacation.
What is the best spa hotel in Tlaxcala?
HOTEL BOUTIQUE CASA DEL BOSQUE is a top spa hotel featuring 15 pools, 3 restaurants, and a bar. Spend an afternoon at the spa where you'll find Swedish massages, deep-tissue massages, and hot stone massages.
How many spa hotels are there in Tlaxcala?
Among Expedia's 41 accommodation options in Tlaxcala, there is 1 spa hotel.
What's there to see and do in Tlaxcala?
Experience Tlaxcala with a stop at Xicotencatl National Park, Xicotencatl Theater, and Basilica of Ocotlan. If you have extra time while you're in the area, you might want to see Government Palace and Constitution Square.
What is a Tlaxcala spa hotel?
Spa hotels in Tlaxcala have on-site spas which offer services like therapies and a selection of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.