St. James, MO Vacation Homes from ￥11,969

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Our top choices for St. James vacation homes

A living room with a sofa, armchair, coffee table, and a rug.

1. Pet-friendly 2BR with fenced yard

Saint James

Richie M.

￥41,182 total

includes taxes & fees

Nov 8 - Nov 9

A modern kitchen with dark cabinetry, a stainless steel sink, a microwave, and a stove.

2. Spacious 3BR near downtown St. James

Saint James

Billy A.

￥43,482 total

includes taxes & fees

Nov 9 - Nov 10

A spacious living area with a sofa, blue armchairs, a coffee table, and a rug.

3. The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James

Saint James

Ellen

￥33,574 total

includes taxes & fees

Nov 9 - Nov 10

A modern kitchen with grey cabinets, a central island, and a dining area with brown chairs.

4. Get Cozy in the Country - The Cottage on Luca Hill

Saint James

K K.

￥35,982 total

includes taxes & fees

Nov 8 - Nov 9

A spacious living room with a ceiling fan, a herringbone-patterned floor, and a large window with sheer curtains.

5. Vineyard Ridge Farmhouse • 3BR • 2BA • Vineyard View • Fire pit •

Saint James

Heather A.

￥36,120 total

includes taxes & fees

Nov 9 - Nov 10

A kitchen with a central island, stainless steel appliances, and a blue-tiled backsplash.

6. 6BR Ozark Retreat on 10 Private Acres - Fire Pits, Game Room & Patio

Saint James

￥117,521 total

includes taxes & fees

Nov 16 - Nov 17

A spacious living room with a grey leather sofa, a coffee table, and a large window with blue curtains.

7. Lakeside Retreat next to Conservation Area

Rolla

sharon m.

￥44,513 total

includes taxes & fees

Nov 16 - Nov 17

A bedroom with a bed, bedside table, bench, and a window with curtains.

8. Simply Sweet 3 Bedroom Home - near MS&T & Fort Leonard Wood

Rolla

Liz H.

￥32,453 total

includes taxes & fees

Nov 23 - Nov 24

A wooden bench with a large mirror, a white vase with flowers, a small wooden sculpture, and a globe.

9. Cozy Home on the edge of Rolla!

Rolla

Jesse C.

￥27,479 total

includes taxes & fees

Nov 11 - Nov 12

10. Farm View/Pool/FirePit/PS4/85"TV

Rolla

Elvina C.

￥76,676 total

includes taxes & fees

Nov 30 - Dec 1

A living room with a grey sofa, a coffee table, and a flat-screen TV. There are two potted plants and a clock on the wall.

11. Cozy 2-Bedroom House in Enchanting Rolla with AC Comfort

Rolla

Kevin R.

￥36,580 total

includes taxes & fees

Nov 16 - Nov 17

A four-poster bed with a wooden finish, a dresser with multiple drawers, and a nightstand.

12. Spacious 4BR near Missouri S&T and downtown Rolla

Rolla

Ruth G.

￥43,338 total

includes taxes & fees

Nov 17 - Nov 18

A house with a gravel driveway, a horse in the background, and a barbecue grill on the porch.

13. Crooked Creek Ranch Farmhouse

Steelville

Irene L.

￥44,777 total

includes taxes & fees

Nov 9 - Nov 10

A kitchen with white cabinets, a microwave, a refrigerator, and a wooden dining table.

14. Cozy 2-bedroom house in Cuba, MO.

Cuba

Ann W.

￥23,146 total

includes taxes & fees

Dec 1 - Dec 2

A spacious living area with a leather sofa, a cowhide rug, and a staircase leading to an upper level.

15. Unique Tiny Home! Lakefront ~ BBQ Grill ~ Couple's Retreat

Bourbon

Wendy L.

￥55,113 total

includes taxes & fees

Nov 17 - Nov 18

A mobile home with a patio area, outdoor seating, and potted plants.

16. #1 Cabin at Red Oak Valley

Canaan Township

Moira M.

￥32,597 total

includes taxes & fees

Nov 11 - Nov 12

A multi-level room with a staircase, a chandelier, and a bed with pillows.

17. Riverbend Getaway 134-Luxury & Comfort sleep 20+ nearby-swim, float, hike, relax

Leasburg

Kayla W.

￥108,457 total

includes taxes & fees

Nov 9 - Nov 10

A room with a wooden wall panel, a flat-screen TV mounted above a wooden console, a white lantern, and a remote control on the console.

18. Delightful 3-bedroom house with AC in charming Davisville many close attractions

Davisville

Karigan C.

￥36,699 total

includes taxes & fees

Dec 1 - Dec 2

A spacious living room with a ceiling fan, a chandelier, a dining area with a red tablecloth, and a sofa.

19. Riverbend Getaway-Adventure awaits- minutes to swim, float, fish, hike and relax

Leasburg

Eli B.

￥89,519 total

includes taxes & fees

Nov 11 - Nov 12

A hot tub with a blue light, surrounded by outdoor furniture and red umbrellas, with a pool and trees in the background.

20. Club Boulders by Pinemark® Heated Pool+Hot Tub

Bourbon

Jen S.

￥98,887 total

includes taxes & fees

Nov 8 - Nov 9

View all properties

Learn more about St. James

Nestled among rolling hills, St. James invites visitors to sample award-winning vintages at St. James Winery and Meramec Vineyards. Families can explore the crystal-clear waters of Maramec Spring Park, where rainbow trout swim beneath historic iron works and hiking trails wind through lush Ozark scenery.

See all hotels in St. James

A wooden bridge over a flowing river with moss-covered rocks.

Top reviews in St. James

A hotel lobby with a reception desk, seating area, and a green glass door.

Hampton Inn Rolla

Rolla

10/10 Excellent

Anonymous traveler

An indoor swimming pool with clear water, surrounded by lounge chairs and tables.

Greenlight Inn & Suites

St. James

10/10 Excellent

Property has recently been updated. Check-in was very easy and gal that checked us in was very sweet and kind. The air conditioning in the first room she gave us was not working so she immediately upgraded us to a suite and it was a lovely room, very clean, spacious and comfortable. They use Dove products in the bottles for soap, shampoo & conditioner which I was thrilled about. The Poole water was lukewarm and we were in the Poole for awhile. Had cable which was nice. Also recommended a nice...

Joyce

A hotel room with a bed, a flat-screen TV, two bedside lamps, a window with curtains, and a cityscape painting on the wall.

Super 8 by Wyndham Cuba

Cuba

10/10 Excellent

Tim

A pool area with a hot tub, seating, and a changing room.

Holiday Inn Express Hotel & Suites Rolla - U of Missouri S&T by IHG

Rolla

10/10 Excellent

Peggy

Owensville Motor Inn

Owensville

10/10 Excellent

Very pleasantly surprised. The staff were incredibly kind and accommodating. We have young children so cleanliness is very important to us. We can’t handle the slightest smell of smoke or mildew, so luckily that was not an issue here. The room smelled like fresh linen upon entering (not like the synthetic air fresheners. It was absolutely the linens themselves), and it was immaculate throughout. No frills and modest as far as decor but for any standards it was a nice, safe, clean, comfortable...

Jeremiah