The Best Business Hotels in Southeast Iowa from ￥13,537 in 2026

A paved courtyard with a brick pathway, trees, and a distant view of a road and buildings.

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Our top choices for Southeast Iowa business-friendly hotels

A lobby with a stone fireplace, comfortable seating, and a flat-screen TV mounted on the wall.

A fire pit surrounded by outdoor furniture, including a sofa and chairs, in a patio area.

A spacious lobby with a leather sofa, dining area, and a TV mounted on a stone wall.

A hotel room with two beds, a television, a desk with a lamp, and a chair.

1. Cobblestone Inn & Suites - Fort Madison

Fort Madison

Elaine

￥14,735

￥16,504 total

includes taxes & fees

Sep 20 - Sep 21

A spacious living area with a wooden staircase, a stone fireplace, and a reception desk.

A hotel room with a bed, a desk, a sofa, a lamp, and a mirror.

A hotel room with two beds, a large window, a standing lamp, and a patterned carpet.

An indoor swimming pool with clear water, surrounded by a white fence, and equipped with multiple entry points and seating areas.

2. Quality Inn & Suites Fort Madison near Hwy 61

Fort Madison

Sharon

￥13,620

￥15,254 total

includes taxes & fees

Sep 27 - Sep 28

A spacious living room with a large sofa, two armchairs, a coffee table, and a fireplace.

A cozy living room with a grey sofa, two patterned armchairs, a wooden coffee table, and a brick accent wall.

A modern kitchen with a granite countertop, wooden chairs, and a large painting of a colorful horse.

A hotel room with a bed, a TV, a desk, and a chair.

3. AmericInn by Wyndham Mount Pleasant

Mount Pleasant

Terri

￥13,054

￥14,621 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with a bed, a sofa, a small table, a chair, a nightstand, and a painting on the wall.

A living room with a sofa, two armchairs, a coffee table with a plant, a lamp, and a TV on the wall.

A home gym with a treadmill, elliptical, and stationary bike, a large mirror, and a framed picture on the wall.

A modern reception area with a dark granite counter, light-colored walls, and a seating area with a sofa and chairs.

4. Best Western Mt. Pleasant Inn

Mount Pleasant

Paul

￥12,086

￥13,537 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with two beds, a desk, a chair, and a large window.

A bathroom with a bathtub, toilet, and sink.

A reception area with a white sofa, a potted plant, and a framed picture on the wall.

A Super 8 motel with a brick facade, a covered entrance, and a parking lot with cars.

5. Super 8 by Wyndham Mt Pleasant

Mount Pleasant

frank

￥13,186

￥14,768 total

includes taxes & fees

Sep 20 - Sep 21

A row of single-family homes with a well-maintained lawn and a tree in the foreground.

A compact kitchen with wooden cabinets, a microwave, a coffee maker, and a dishwasher.

A living room with a sofa, a patterned armchair, a dining table with chairs, a kitchen area with wooden cabinets and a refrigerator, and a television on a stand.

A modern kitchen with wooden cabinets, a white countertop, and a dining area with a white table and chairs.

6. Nauvoo Vacation Villas & Condos

Nauvoo

Renae

￥22,339

￥23,675 total

includes taxes & fees

Sep 21 - Sep 22

An indoor swimming pool with a wooden ceiling, grey tiled floor, and several lounge chairs and tables around the pool area.

A multi-story hotel with a central entrance, a parking lot, and a clear sky.

A modern hotel lobby with blue and pink seating, a central coffee table, and a kitchen area in the background.

A hotel room with a large bed, a desk with a computer, a chair, a window with curtains, and a view of the city.

7. Quality Inn & Suites Keokuk North

Keokuk

Susan

￥16,192

￥18,135 total

includes taxes & fees

Oct 11 - Oct 12

A large indoor swimming pool with a lifeguard chair, poolside chairs, and a view of the outside through large windows.

A Hampton Inn hotel with a covered entrance, a well-lit facade, and a landscaped front yard.

A breakfast buffet area with a sign reading "EAT HERE" and various food items like cereal and pastries.

A modern hotel room with a large bed, two bedside tables with lamps, a small sofa, and a desk.

8. Hampton Inn Keokuk

Keokuk

Kristopher

￥16,926

￥18,958 total

includes taxes & fees

Oct 10 - Oct 11

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Top Southeast Iowa Hotel Reviews

Best Western Mt. Pleasant Inn

10/10 Excellent

"It was well taken care of, the staff were friendly and helpful. There were shops close by and it was close to the highway for easy access to get back home."

Fun City Resort Hotel

8/10 Good

"Fun experience, dining, casino, pool and arcade all in one!"

Quality Inn & Suites Fort Madison near Hwy 61

10/10 Excellent

"The bed was very comfortable and the breakfast was great."

Quality Inn & Suites Mount Pleasant

10/10 Excellent

"The room did feel a little damp and smelled a little musty. Other than that, everything was great!"

Comfort Suites Burlington

8/10 Good

"Rooms were clean, the lady at desk when we checked in wasn't very friendly and didn't greet us or acknowledge us until she finished texting on her phone which was about 5 to 10min."

Baymont by Wyndham Keokuk

8/10 Good

"Pool was closed"

Frequently asked questions

How much do business-friendly hotels in Southeast Iowa cost?

Expect to pay between ￥13,537 and ￥25,017 per night for business-friendly hotels in Southeast Iowa. Awesome deals on stays that are suitable for corporate travelers are a click away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

How many business-friendly hotels are there in Southeast Iowa?

Southeast Iowa has 17 business-friendly hotels to choose from. Whether you're attending a conference or working remotely, these properties are equipped with everything you need to be productive.

Why book your business-friendly hotel in Southeast Iowa with Expedia?

Expedia will help you find a fabulous business-friendly hotel when work takes you on the road. From free WiFi and parking to gyms and spas, our stays come with all you'll need to settle that big contract.

How can I find cheap business-friendly hotels in Southeast Iowa?

Expedia can help you easily find cheap business-friendly hotels in Southeast Iowa. Simply head to the "traveler experience" filter and click on "business friendly." This will show you properties with amenities designed to help you work comfortably and efficiently, like included breakfast and free WiFi. You can also choose your hotel star rating and budget to keep costs down.

What is there to do in Southeast Iowa near my business-friendly hotel?

You'll find tons of attractions to see during your time in Southeast Iowa. If you've planned a couple of nights in Nauvoo, Rheinberger House Museum is a must-see.

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Check availability on Southeast Iowa Business Hotels

Our top choices for Southeast Iowa business-friendly hotels

1. Cobblestone Inn & Suites - Fort Madison