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Our top choices for Santo Antonio luxury hotels

Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world

Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world
5.0 star property
Lisbon City Center
9.0 out of 10, Wonderful, (1002)
"Had a lovely three night stay The staff members were "
Canada
Gloria
The price is ¥54,533
¥59,264 total
includes taxes & fees
Dec 20 - Dec 21
Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world

Valverde Lisboa Hotel & Garden - Relais & Châteaux

Valverde Lisboa Hotel & Garden - Relais & Châteaux
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (496)
"Excellent staff and wonderful stay all around."
United States
Donald
The price is ¥44,522
¥48,652 total
includes taxes & fees
Dec 14 - Dec 15
Valverde Lisboa Hotel & Garden - Relais & Châteaux

EPIC SANA Marques Hotel

EPIC SANA Marques Hotel
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (1288)
"Great location, spacious rooms, the staff was all amazing and very sweet and friendly "
United States
Georgina Moyers
The price is ¥38,992
¥42,790 total
includes taxes & fees
Dec 19 - Dec 20
EPIC SANA Marques Hotel

Memmo Príncipe Real - Design Hotels

Memmo Príncipe Real - Design Hotels
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (319)
"Nice Location and staff very friendly."
United States
mohammed
The price is ¥43,324
¥47,382 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Memmo Príncipe Real - Design Hotels

Hotel das Amoreiras - Small Luxury Hotels of the World

Hotel das Amoreiras - Small Luxury Hotels of the World
4.0 star property
Lisbon City Center
10.0 out of 10, Exceptional, (100)
"Beautiful hotel, nice staff, but the location is quite far away from the spots "
Hong Kong SAR China
Lavanna
The price is ¥36,037
¥39,659 total
includes taxes & fees
Dec 17 - Dec 18
Hotel das Amoreiras - Small Luxury Hotels of the World

TURIM Boulevard Hotel

TURIM Boulevard Hotel
5.0 star property
Lisbon City Center
9.2 out of 10, Wonderful, (394)
"Friendly staff, good breakfast, excellent location "
United States
Massiel
The price is ¥36,475
¥40,122 total
includes taxes & fees
Jan 11 - Jan 12, 2026
TURIM Boulevard Hotel

EPIC SANA Lisboa Hotel

EPIC SANA Lisboa Hotel
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (1003)
"We were lucky enough to stay at the hotel twice and found the staff really helpful the rooms spotless and the ambience terrific. "
United Kingdom
Peter
The price is ¥36,103
¥39,728 total
includes taxes & fees
Dec 20 - Dec 21
EPIC SANA Lisboa Hotel

The Vintage Hotel & Spa - Lisbon

The Vintage Hotel & Spa - Lisbon
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (324)
"great holiday venue.great staff.great food"
United Kingdom
John
The Vintage Hotel & Spa - Lisbon

Altis Grand Hotel

Altis Grand Hotel
5.0 star property
Lisbon City Center
9.2 out of 10, Wonderful, (1003)
"Friendly staff and very clean rooms"
Canada
Manraj Singh
The price is ¥27,508
¥30,616 total
includes taxes & fees
Dec 25 - Dec 26
Altis Grand Hotel

Browns Avenue Hotel

Browns Avenue Hotel
5.0 star property
Lisbon City Center
9.4 out of 10, Exceptional, (287)
" Breakfast was healthy and great quality foods, staff are a real asset to Brown hotel, super friendly and very nice, amazing service. Would definitely come back and highly recommend."
United States
Hassna
The price is ¥25,413
¥28,397 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Browns Avenue Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Santo Antonio Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your stay in Santo Antonio?
Travel to Humberto Delgado Airport (LIS) Airport or Cascais (CAT) Airport, and then treat yourself to a stay at one of 17 Santo Antonio luxury hotels. During your visit, you might want to enjoy the spas and art which Santo Antonio is known for.
What's the best luxury accommodation in Santo Antonio?
EPIC SANA Marques Hotel is a luxury hotel with 2 restaurants and 2 bars, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Altis Grand Hotel and PortoBay Liberdade are other upscale choices for your vacation.
How many luxury hotels will I be able to find in Santo Antonio?
Lie in the lap of luxury during your getaway to Santo Antonio in one of Expedia's 17 luxury hotels.
When can I expect good weather in Santo Antonio?
Planning for the weather is an important factor for making your trip to Santo Antonio a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 70°F, while the coldest months are February and January with an average of 55°F. Average annual precipitation for Santo Antonio is 23 inches.
What's there to see and do in Santo Antonio?
When you're in Santo Antonio, enjoy exploring the sights and attractions here including Avenida da Liberdade, Marquis of Pombal Square, and Medeiros e Almeida Museum. If you have extra time while you're in the area, you might want to stop by Cinemateca Portuguesa Museum and Coracao de Jesus.
How can I get around Santo Antonio?
It's easier to get around town in style when you know your options. Nearby metro stations include Avenida Station, Marques de Pombal Station, and Rato Station.