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Compare 61 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Lewis and Clark Resort
32-inch LCD TV with digital channels, TV

Lewis and Clark Resort

2.5 star property
8.8 out of 10, Excellent, (264)
"I stay here every two years. It's perfect for the price and any outdoorsmen."
Lewis and Clark Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Lewis and Clark Resort

Lewis and Clark Resort

10/10 Excellent
"Great accommodations"
Thomas 1-night trip
Posted 1 day ago
Lewis and Clark Resort

More cheap stays in Santee

More cheap stays in Santee

Lewis and Clark Resort

Lewis and Clark Resort

43496 Shore Drive, Yankton, SD
Get rates
8.6/10 Excellent! (264 reviews)

Frequently asked questions

What are some of the best vacation rentals that Santee has to offer?

Gavins Point Lakehouse: This vacation home rental near Santee offers a fireplace, a balcony, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. See all vacation rentals in Santee.

If I need to cancel my hotel reservation in Santee, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable as long as you cancel before the hotel’s cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santee.

Where can I learn more about changing or cancelling my trip to Santee?

For more information about rescheduling or cancelling your trip to Santee, click here.

What is staying in Santee like?

Those traveling to Santee are sure to enjoy the sights to see and things to do. There are 61 hotels and other accommodations in the surrounding area. Find out more about Santee.

What are the top places to visit in Santee?

A favorite place to visit is Lewis and Clark Lake. You'll also find Niobrara State Park and Lewis and Clark Recreation Area in the area. Check out what more to see and do in Expedia's Santee guide.

What's the weather like in Santee?

The hottest months are usually July and August with an average temp of 72°F, while the coldest months are January and February with an average of 26°F. The snowiest months in Santee are January, December, October, and March, with each month seeing an average of 8 inches of snowfall.

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