Find hotels in Santa María Mixtequilla from ¥5,130

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa María Mixtequilla hotels

Hotel Calli

Hotel Calli
3.5 star property
Tehuantepec
9.0 out of 10, Wonderful, (88)
"Property was nice and well maintained. Nice outside pool. Breakfast was available for a price. "
United States
Angel
The price is ¥8,477
¥10,088 total
includes taxes & fees
Dec 17 - Dec 18
Hotel Calli

Hotel Central

Hotel Central
3.0 star property
Juchitan de Zaragoza
8.6 out of 10, Excellent, (84)
"Perfect hotel!"
Belgium
Lukas
The price is ¥6,725
¥8,003 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Hotel Central

Punta Conejo Resort

Punta Conejo Resort
3.0 star property
Salina Cruz
7.2 out of 10, Good, (12)
"If you want to get off the grid and feel isolated with ocean front accommodations, this is the spot . "
United States
Anonymous traveler
Punta Conejo Resort

Hotel Boutique Alebrijes Salina Cruz

Hotel Boutique Alebrijes Salina Cruz
3.0 star property
Salina Cruz
9.4 out of 10, Exceptional, (18)
"The room was clean and the housekeeping lady was friendly and helpful."
United States
Jaymie
The price is ¥6,828
¥8,125 total
includes taxes & fees
Dec 22 - Dec 23
Hotel Boutique Alebrijes Salina Cruz

Hotel Express Inn Juchitan

Hotel Express Inn Juchitan
2.5 star property
Juchitan de Zaragoza
7.8 out of 10, Good, (19)
"Ok"
Mexico
obed
Hotel Express Inn Juchitan

Hotel De La Peña Inn

Hotel De La Peña Inn
3.0 star property
Santa María
8.2 out of 10, Very Good, (36)
"Highly recommend this place for the price. Friendly professional staff. Clean room and super comfy bed. Nice bathroom. The location is a little odd being on a sort of roundabout, but as I was in town to visit the ruins of Guiengola it was ideal for me. Can't fault the plaxe "
United Kingdom
Ralph
Hotel De La Peña Inn

Bungalows Punta Conejo

Bungalows Punta Conejo
3.0 star property
Salina Cruz
9.2 out of 10, Wonderful, (10)
"The shower had a very bad water flow. When we arrived, there were no towels and toilet-paper in the room. At the end we could almost not pay with our creditcard (raison ??) But the breakfast was very good! Thank you"
Mexico
Hans
The price is ¥7,759
¥9,233 total
includes taxes & fees
Dec 17 - Dec 18
Bungalows Punta Conejo

Sicarú

Sicarú
2.0 star property
Salina Cruz
9.0 out of 10, Wonderful, (14)
"Very clean, comfortable, and well located hotel in the heart of downtown Salina Cruz, Oaxaca, México. Nice price, very acceptable."
Mexico
John
The price is ¥6,035
¥7,182 total
includes taxes & fees
Dec 15 - Dec 16
Sicarú

Hotel Santa Cruz Juchitan

Hotel Santa Cruz Juchitan
3.0 star property
Juchitan de Zaragoza
7.8 out of 10, Good, (111)
"Being the only hotel in town, it was fine."
United States
Tony
Hotel Santa Cruz Juchitan

Hotel Express Inn Ixtepec

Hotel Express Inn Ixtepec
3.0 star property
Ixtepec
7.4 out of 10, Good, (54)
"Express Inn is quiet , clean , and comfortable. The location is great for dining and shopping. A very fun little town "
United States
Tami
Hotel Express Inn Ixtepec

Casa Majeva

Casa Majeva
3.0 star property
Salina Cruz
10.0 out of 10, Exceptional, (3)
"The property is truly a gem in quite a remote area. As it is a non season, everything is closed, but this hotel is working and that is nice. But actually besides its teritory there is nothing to do there. The owner is extremely nice and chatty! It gives property a lot if charm. Other staff members unfortunatelly really dont speak english much so the communication is very limited. Well, almost like in all Mexico. Overall nice pool and interior in the apartments, would be great to have some...
United States
Vismante
The price is ¥18,258
¥21,727 total
includes taxes & fees
Dec 15 - Dec 16
Casa Majeva

One Salina Cruz

One Salina Cruz
3.0 star property
Salina Cruz
9.0 out of 10, Wonderful, (421)
"Excelente "
Mexico
Elizabeth Yazmin
The price is ¥7,922
¥9,442 total
includes taxes & fees
Dec 17 - Dec 18
One Salina Cruz

City Express by Marriott Salina Cruz

City Express by Marriott Salina Cruz
3.5 star property
Salina Cruz
8.4 out of 10, Very Good, (308)
"Excelente"
Mexico
Yeeviani
The price is ¥8,860
¥10,544 total
includes taxes & fees
Dec 16 - Dec 17
City Express by Marriott Salina Cruz

Casa de Huéspedes Juanita

Casa de Huéspedes Juanita
2.5 star property
Salina Cruz
7.2 out of 10, Good, (17)
"To rest its okay, there’s nothing to enjoy or feel surprised by the are. "
United States
Juana
The price is ¥4,311
¥5,130 total
includes taxes & fees
Dec 15 - Dec 16
Casa de Huéspedes Juanita

Hotel Calendas

Hotel Calendas
2.5 star property
Salina Cruz
7.8 out of 10, Good, (27)
"The antique look and all the beautiful historical pictures"
United States
Veronica
Hotel Calendas

Hotel San Francisco

Hotel San Francisco
2.5 star property
Salina Cruz
8.0 out of 10, Very Good, (94)
"One scorpion in the towel up my bed "
United States
Mariano
The price is ¥6,871
¥8,176 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Hotel San Francisco

Gran Hotel Don Nacho

Gran Hotel Don Nacho
3.5 star property
Salina Cruz
7.2 out of 10, Good, (27)
"Excelente "
Mexico
Javier
The price is ¥13,841
¥16,471 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Gran Hotel Don Nacho

HOTEL CASA TERESA GALERIA CAFE

HOTEL CASA TERESA GALERIA CAFE
3.0 star property
Juchitan de Zaragoza
7.2 out of 10, Good, (18)
"Very nice owners who helped us in many ways including personally driving us to the bus station when our taxi did not arrive on time to make sure we did not miss our bus to San Cristobal."
United States
jeffrey
HOTEL CASA TERESA GALERIA CAFE
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa María Mixtequilla Hotel Reviews

More cheap stays in Santa María Mixtequilla

Frequently asked questions

What's the best place to stay in Santa María Mixtequilla?
One Salina Cruz, located 14.1 mi (22.7 km) from the heart of Santa María Mixtequilla, is a top choice for your stay based on our traveler data. Other good options for your stay in the area are Hotel Santa Cruz Juchitan and City Express by Marriott Salina Cruz. See all available top hotels, or vacation rentals in Santa María Mixtequilla.
What are some of the best vacation rentals in Santa María Mixtequilla?
House with pool a few meters from the beach come and rest!!!: This vacation home rental outside of Santa María Mixtequilla is equipped with an outdoor pool, air-conditioning, and WiFi to help you feel comfortable during your stay. See all vacation rentals in Santa María Mixtequilla.
If I need to cancel my hotel reservation in Santa María Mixtequilla, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa María Mixtequilla.
Where can I learn more about changing or cancelling my trip to Santa María Mixtequilla?
For additional details about updating your trip to Santa María Mixtequilla or cancelling it, click here.
What is staying in Santa María Mixtequilla like?
Travelers to Santa María Mixtequilla will find plenty to explore and enjoy. There are 23 hotels and other accommodations in the surrounding area. Find out more about Santa María Mixtequilla.
What are the top places to visit in Santa María Mixtequilla?
Places to visit in the wider area include Tehuantepec House of Culture, Las Escolleras Beach, and Guiengola. You'll also find Jardín Juárez and Salina Cruz Lighthouse in the area. Check out what more to see and do in Expedia's Santa María Mixtequilla guide.
What's the seasonal weather like in Santa María Mixtequilla?
The hottest months are usually May and April with an average temp of 83°F, while the coldest months are January and December with an average of 77°F. The rainiest months in Santa María Mixtequilla are September, June, August, and July, with each month seeing an average of 8 inches of rainfall.

Explore a world of travel with Expedia