Find hotels in Santa Cruz de la Sierra from ￥8,206

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Mar 16 - Mar 17
Tomorrow
Mar 17 - Mar 18
This weekend
Mar 20 - Mar 22
Next weekend
Mar 27 - Mar 29

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Cruz de la Sierra hotels

Terrace/patio

Hospedium Hotel Soterraña

Hospedium Hotel Soterraña
3.0 star property
Madronera
8.8 out of 10, Excellent, (38 reviews)
"Tiene aparcamiento propio gratuito, la habitación muy bien y el personal excelente. Si restaurante muy buena calidad y buena atención. "
Spain
Ángel
The price is ￥10,677
￥11,744 total
includes taxes & fees
Mar 18 - Mar 19
Hospedium Hotel Soterraña
Garden

Finca la Desa

Finca la Desa
3.0 star property
Miajadas
9.8 out of 10, Exceptional, (8 reviews)
"La habitación es muy cómoda y moderna, con varios elementos domóticos. El personal es muy atento y muy amable."
Spain
Josué
The price is ￥12,599
￥13,859 total
includes taxes & fees
Mar 18 - Mar 19
Finca la Desa
Exterior

Eurostars Palacio Santa Marta

Eurostars Palacio Santa Marta
4.0 star property
Trujillo
9.2 out of 10, Wonderful, (336 reviews)
"Great hotel, with private parking. Good breakfast, comfy bed and excellent shower. The hotel is very well placed for visiting the castle etc and lots of restaurants/ cafes in the immediate area."
United Kingdom
Sylvia
The price is ￥12,433
￥13,677 total
includes taxes & fees
Mar 23 - Mar 24
Eurostars Palacio Santa Marta
Exterior

Parador de Trujillo

Parador de Trujillo
4.0 star property
Trujillo
9.2 out of 10, Wonderful, (225 reviews)
"Very nice hotel, good parking, well located, "
United States
Edgar
The price is ￥11,412
￥12,553 total
includes taxes & fees
Mar 17 - Mar 18
Parador de Trujillo
Exterior

Finca El Azahar

Finca El Azahar
3.0 star property
Trujillo
10.0 out of 10, Exceptional, (6 reviews)
"Stunning, warm, beautiful, "
Canada
Alex
The price is ￥26,180
￥28,798 total
includes taxes & fees
Mar 18 - Mar 19
Finca El Azahar
Breakfast, lunch, dinner served; Regional cuisine

Hostal Hueso

Hostal Hueso
2.0 star property
Trujillo
8.2 out of 10, Very Good, (23 reviews)
"Excelent location, excelent staf"
United States
ALFRED
The price is ￥9,118
￥10,030 total
includes taxes & fees
Mar 17 - Mar 18
Hostal Hueso
Interior

Plaza Sandra

Plaza Sandra
3.0 star property
Trujillo
9.6 out of 10, Exceptional, (52 reviews)
"Good staff and beautiful place "
United States
Juan
The price is ￥9,410
￥10,351 total
includes taxes & fees
Mar 17 - Mar 18
Plaza Sandra
Ballroom

Hotel Izan Trujillo

Hotel Izan Trujillo
4.0 star property
Trujillo
8.8 out of 10, Excellent, (211 reviews)
"Friendly staff, good buffet breakfast, comfortable room. "
United Kingdom
Malcolm
The price is ￥12,643
￥13,908 total
includes taxes & fees
Mar 17 - Mar 18
Hotel Izan Trujillo
Restaurant

Casa Rural Las Canteras

Casa Rural Las Canteras
3.0 star property
Trujillo
8.2 out of 10, Very Good, (33 reviews)
"Limpieza correcta "
Spain
Carlos
The price is ￥14,755
￥16,230 total
includes taxes & fees
Mar 17 - Mar 18
Casa Rural Las Canteras
Restaurant

Hostal León

Hostal León
2.0 star property
Trujillo
7.6 out of 10, Good, (52 reviews)
"Bien "
Spain
Antonio Manuel
The price is ￥9,118
￥10,030 total
includes taxes & fees
Mar 17 - Mar 18
Hostal León
Lunch and dinner served

Hospedium Hotel Triana

Hospedium Hotel Triana
3.0 star property
Miajadas
7.8 out of 10, Good, (19 reviews)
"This is a very convenient stop-over between Santander and Barbate/Vejer/Conil where we were staying. Simple, clean room,super helpful staff and great food at an amazing price. Free car parking in a plot next to the hotel. We've stayed here before and will do so again."
United Kingdom
tina
The price is ￥12,812
￥14,094 total
includes taxes & fees
Mar 17 - Mar 18
Hospedium Hotel Triana
Double Room | Free WiFi, bed sheets

Hostal Ruralis Altozano

Hostal Ruralis Altozano
1.0 star property
Montánchez
The price is ￥7,460
￥8,206 total
includes taxes & fees
Mar 17 - Mar 18
Hostal Ruralis Altozano
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Santa Cruz de la Sierra

Head to Juan Pizarro de Orellana Palace and Plaza Mayor—just two of the sights around Santa Cruz de la Sierra.

See all hotels in Santa Cruz de la Sierra
Catedral de Santa Cruz de la Sierra

Top Santa Cruz de la Sierra Hotel Reviews

Finca la Desa

Finca la Desa

10/10 Excellent
"This is a diamond in the west country of Spain. Everything about this place was exceptional."
Craig 1-night trip
Posted 2 days ago
Finca la Desa

More cheap stays in Santa Cruz de la Sierra

Hostal Hueso

Hostal Hueso

Calle Arquillo, 4 Trujillo Cáceres
The price is ￥9,118 per night from Mar 17 to Mar 18
￥9,118
￥10,030 total
Mar 17 - Mar 18
includes taxes & fees
8.2/10 Very Good! (23 reviews)

Frequently asked questions

What's the best place to stay in Santa Cruz de la Sierra?
Eurostars Palacio Santa Marta, located 0.1 mi (0.1 km) from the heart of Santa Cruz de la Sierra, is a top choice for your stay based on our traveler data. Other good options for your stay in the area are Parador de Trujillo and Hotel Izan Trujillo. See all available top hotels, or vacation rentals in Santa Cruz de la Sierra.
What's the top vacation rental in Santa Cruz de la Sierra?
Rural house with swimming pool El Huerto del Olivo, Plasenzuela, Trujillo, Cáceres: This vacation home near Santa Cruz de la Sierra is equipped with a barbecue grill, air-conditioning, and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a dishwasher, a stovetop, and a microwave. See all vacation rentals in Santa Cruz de la Sierra.
If I need to cancel my hotel reservation in Santa Cruz de la Sierra, will I receive a refund?
Yes! Most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz de la Sierra.
Where can I learn more about changing or cancelling my trip to Santa Cruz de la Sierra?
To find more details about updating your trip to Santa Cruz de la Sierra or cancelling it, head over to our customer service page.
What are some accommodations with pools in Santa Cruz de la Sierra?
Eurostars Palacio Santa Marta: Offers complimentary wireless internet access, a seasonal outdoor pool, and televisions. Another choice that features an onsite pool is Rural house (full rental) El Olivar del Marqués for 26 people. View all hotels with pools in Santa Cruz de la Sierra.
What's the best accommodation near Adolfo Suarez Madrid-Barajas Airport (MAD)?
Madrid Marriott Auditorium Hotel & Conference Center is a popular 4-star hotel featuring 2 restaurants and 2 bars. It's located a short 1.4 mi (2.2 km) from Adolfo Suarez Madrid-Barajas Airport. Other accommodations close to the airport are Hotel Clement Barajas and Meliá Barajas.
What's it like to stay in Santa Cruz de la Sierra?
Those traveling to Santa Cruz de la Sierra are sure to enjoy the sights to see and things to do. In Santa Cruz de la Sierra, there are 9 hotels and other accommodations to choose from. Find out more about Santa Cruz de la Sierra.
What is there to see in Santa Cruz de la Sierra?
Places to visit in the wider area include Juan Pizarro de Orellana Palace, Plaza Mayor, and Statue of Francisco Pizarro. You'll also find Trujillo Castle and Museo de Vino y Queso in the area. Check out what more to see and do in Expedia's Santa Cruz de la Sierra guide.
What's the seasonal weather like in Santa Cruz de la Sierra?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 47°F. Average annual precipitation for Santa Cruz de la Sierra is 22 inches.