A large brick church with two bell towers and palm trees in front.

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Sep 19 - Sep 20
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Sep 20 - Sep 21
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Sep 25 - Sep 27
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Oct 2 - Oct 4

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Our top choices for Santa Cruz de la Sierra hotels

Terrace/patio
Restaurant
Outdoor dining
Restaurant

1. Hospedium Hotel Soterraña

Hospedium Hotel Soterraña
Madronera
United States
Jose Luis
￥10,893
￥11,983 total
includes taxes & fees
Oct 12 - Oct 13
Hospedium Hotel Soterraña
Garden
Single Room | In-room safe, iron/ironing board, WiFi (free)
Restaurant
Food court

2. Finca la Desa

Finca la Desa
Miajadas
New Zealand
Craig
￥11,440
￥12,584 total
includes taxes & fees
Oct 20 - Oct 21
Finca la Desa
Breakfast, lunch and dinner served
Bar (on property)
Interior
Exterior

3. Hostal Hueso

Hostal Hueso
Trujillo
United States
ALFRED
￥10,577
￥11,635 total
includes taxes & fees
Sep 29 - Sep 30
Hostal Hueso
Exterior
Lobby
Bar (on property)
Outdoor pool

4. Eurostars Palacio Santa Marta

Eurostars Palacio Santa Marta
Trujillo
United States
Ana
￥12,120
￥13,333 total
includes taxes & fees
Oct 4 - Oct 5
Eurostars Palacio Santa Marta
Ballroom
Indoor wedding
Seasonal outdoor pool, sun loungers
Hallway

5. Hotel Izan Trujillo

Hotel Izan Trujillo
Trujillo
Spain
Monica
￥13,742
￥15,117 total
includes taxes & fees
Oct 20 - Oct 21
Hotel Izan Trujillo
Exterior
Interior
Flat-screen TV
Property grounds

6. Finca El Azahar

Finca El Azahar
Trujillo
Canada
Alex
￥24,271
￥26,698 total
includes taxes & fees
Oct 15 - Oct 16
Finca El Azahar
Apartment | Soundproofing, WiFi (free), bed sheets
Exterior detail
Hallway
Apartment | Private kitchen

7. Hostal Ruralis Altozano

Hostal Ruralis Altozano
Montánchez
Spain
MARCO ANTONIO
￥6,786
￥7,464 total
includes taxes & fees
Oct 15 - Oct 16
Hostal Ruralis Altozano
Comfort Room | Memory foam beds, desk, WiFi (free)
Comfort Room | Memory foam beds, desk, WiFi (free)
Comfort Twin Room | Bathroom | Bathtub, deep soaking tub, free toiletries, towels
Comfort Room | Memory foam beds, desk, WiFi (free)

8. Alojamientos Plaza Mayor

Alojamientos Plaza Mayor
Trujillo
United States
Adela
￥5,705
￥6,276 total
includes taxes & fees
Sep 22 - Sep 23
Alojamientos Plaza Mayor
Exterior
Outdoor pool, open 10:30 AM to 9:00 PM, pool umbrellas, sun loungers
Hallway
Bar (on property)

9. Parador de Trujillo

Parador de Trujillo
Trujillo
United States
wilton
￥15,951
￥17,546 total
includes taxes & fees
Oct 1 - Oct 2
Parador de Trujillo
Interior
Reception
Hallway
Outdoor pool, sun loungers

10. Plaza Sandra

Plaza Sandra
Trujillo
United States
Ismael
￥9,705
￥10,675 total
includes taxes & fees
Oct 14 - Oct 15
Plaza Sandra
Restaurant
Interior
Exterior
Desk, WiFi (free), individually decorated, bed sheets

11. Hostal León

Hostal León
Trujillo
United Kingdom
Gareth
￥8,950
￥9,845 total
includes taxes & fees
Sep 20 - Sep 21
Hostal León
Lunch and dinner served
Superior Double Room, Jetted Tub | Minibar, in-room safe, WiFi (free), bed sheets
Front of property
Coffee shop

12. Hospedium Hotel Triana

Hospedium Hotel Triana
Miajadas
United Kingdom
tina
￥12,933
￥14,227 total
includes taxes & fees
Sep 29 - Sep 30
Hospedium Hotel Triana
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Learn more about Santa Cruz de la Sierra

Head to Palacio de la Conquista and Plaza Mayor—just two of the sights around Santa Cruz de la Sierra.

See all hotels in Santa Cruz de la Sierra
A large brick church with two bell towers and palm trees in front.

Top Santa Cruz de la Sierra Hotel Reviews

Hotel Izan Trujillo

Hotel Izan Trujillo

10/10 Excellent
"Nice hotel with a secure room for cycles for those on tour like me. Nice rooms and good facilities. Restaurant is good but also great places to eat on the Plaza."
Mark 1-night trip
Posted 1 month ago
Hotel Izan Trujillo
Parador de Trujillo

Parador de Trujillo

10/10 Excellent
"We had half board abd the meal was fantastic. I had the selection of meats to start and my wife had a sort of tomato mousse. The olive oil was out of this world and my main course fillet was one of the best that I have ever had. We have been trying to find a reason to travel that way again and wish we had booked for 2 nights or more. It’s a lovely little town, with a beautiful square. A great place as a base to visit Caceres or Guadalupe. We will definitely return!"
Gary 1-night trip
Posted 1 month ago
Parador de Trujillo
Plaza Sandra

Plaza Sandra

10/10 Excellent
"Era un lugar limpio y acogedor, y había muchos sitios a los que se podía ir andando. El personal fue muy atento. Aparcar fue todo un reto, sobre todo cerca del mercado semanal. Pasamos una estancia muy agradable."
Alexandra 3-night trip
Posted 3 months ago
Plaza Sandra
Eurostars Palacio Santa Marta

Eurostars Palacio Santa Marta

10/10 Excellent
"We had a wonderful stay at Eurostars Palacio Santa Marta. The hotel is set inside a beautifully restored historic building just steps from Plaza Mayor, making it perfect for exploring Trujillo on foot. Our room was spacious, comfortable, and very quiet. Alba was warm, welcoming, and made everything easy. Overall, an excellent stay in a charming location — we’d happily return."
Ismael 1-night trip
Posted 4 months ago
Eurostars Palacio Santa Marta

More cheap stays in Santa Cruz de la Sierra

Hostal León

Hostal León

Campillo 11 Trujillo Caceres
￥8,950
￥9,845 total
Sep 20 - Sep 21
includes taxes & fees
7.6/10 Good! (55 reviews)
Hostal León
Hostal Hueso

Hostal Hueso

Calle Arquillo, 4 Trujillo Cáceres
￥10,577
￥11,635 total
Sep 29 - Sep 30
includes taxes & fees
8.2/10 Very Good! (26 reviews)
Hostal Hueso
Posada dos Orillas

Posada dos Orillas

Calle Cambrones N6-8 Trujillo
Get ratesPosada dos Orillas
Hostal San Miguel

Hostal San Miguel

Plaza San Miguel, 3 Trujillo Caceres
Get rates
8.4/10 Very Good! (51 reviews)
Hostal San Miguel
HOTEL RURAL EL LABRIEGO BY VIVERE STAYS

HOTEL RURAL EL LABRIEGO BY VIVERE STAYS

C. Tiendas 7 Plasenzuela Cáceres
Get rates
9.2/10 Wonderful! (19 reviews)
HOTEL RURAL EL LABRIEGO BY VIVERE STAYS
Hostal - Restaurante Emilia

Hostal - Restaurante Emilia

PLAZA DEL CAMPILLO, 28 Trujillo CACERES
Get rates
9.2/10 Wonderful! (22 reviews)
Hostal - Restaurante Emilia

Frequently asked questions

What's the best place to stay in Santa Cruz de la Sierra?
Hotel Izan Trujillo, located 0.1 mi (0.1 km) from the heart of Santa Cruz de la Sierra, is a top choice for your stay based on our traveler data. Other good options for your stay in the area are Eurostars Palacio Santa Marta and Parador de Trujillo. See all available top hotels, or vacation rentals in Santa Cruz de la Sierra.
What's the top vacation rental in Santa Cruz de la Sierra?
Rural house with swimming pool El Huerto del Olivo, Plasenzuela, Trujillo, Cáceres: This vacation home near Santa Cruz de la Sierra is equipped with a barbecue grill, air-conditioning, and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a dishwasher, a stovetop, and a microwave. See all vacation rentals in Santa Cruz de la Sierra.
If I need to cancel my hotel reservation in Santa Cruz de la Sierra, will I receive a refund?
Yes! Most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz de la Sierra.
Where can I learn more about changing or cancelling my trip to Santa Cruz de la Sierra?
To find more details about updating your trip to Santa Cruz de la Sierra or cancelling it, head over to our customer service page.
What are some accommodations with pools in Santa Cruz de la Sierra?
Hotel Izan Trujillo: Offers complimentary wired internet access, a seasonal outdoor pool, and LED televisions. Another choice that features an onsite pool is Rural house (full rental) El Olivar del Marqués for 26 people. View all hotels with pools in Santa Cruz de la Sierra.
What's the best accommodation near Adolfo Suarez Madrid-Barajas Airport (MAD)?
Madrid Marriott Auditorium Hotel & Conference Center is a popular 4-star hotel featuring 2 restaurants and 2 bars. It's located a short 1.4 mi (2.2 km) from Adolfo Suarez Madrid-Barajas Airport. Other accommodations close to the airport are Hotel Clement Barajas and Meliá Barajas.
What's it like to stay in Santa Cruz de la Sierra?
Those traveling to Santa Cruz de la Sierra are sure to enjoy the sights to see and things to do. In Santa Cruz de la Sierra, there are 9 hotels and other accommodations to choose from. Find out more about Santa Cruz de la Sierra.
What is there to see in Santa Cruz de la Sierra?
Places to visit in the wider area include Palacio de la Conquista, Plaza Mayor, and Trujillo Castle. You'll also find Museo de Vino y Queso and Juan Pizarro de Orellana Palace in the area. Check out what more to see and do in Expedia's Santa Cruz de la Sierra guide.
What's the seasonal weather like in Santa Cruz de la Sierra?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 47°F. Average annual precipitation for Santa Cruz de la Sierra is 22 inches.

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