A large brick church with two bell towers and palm trees in front.

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Our top choices for Santa Cruz de la Sierra hotels

1. Hospedium Hotel Soterraña

Hospedium Hotel Soterraña
3.0 star property
Madronera
8.8 out of 10, Excellent, (41 reviews)
"The staff was friendly and helpful, the rooms clean. The food was also good. We liked the location, minutes away drive to Trujillo and a great stop if coming from a city like Sevilla heading to Madrid. We enjoyed our stay !"
United States
Jose Luis
The price is ¥10,121
¥11,133 total
includes taxes & fees
Nov 4 - Nov 5
Hospedium Hotel Soterraña

2. Parador de Trujillo

Parador de Trujillo
4.0 star property
Trujillo
9.2 out of 10, Wonderful, (250 reviews)
"This parador is a nice surprise. Excellent in every aspect"
United States
wilton
The price is ¥12,067
¥13,274 total
includes taxes & fees
Nov 4 - Nov 5
Parador de Trujillo

3. Finca El Azahar

Finca El Azahar
3.0 star property
Trujillo
10.0 out of 10, Exceptional, (7 reviews)
"Stunning, warm, beautiful, "
Canada
Alex
The price is ¥24,168
¥26,585 total
includes taxes & fees
Dec 1 - Dec 2
Finca El Azahar

4. Hotel Izan Trujillo

Hotel Izan Trujillo
4.0 star property
Trujillo
8.6 out of 10, Excellent, (218 reviews)
"Lovely staff and great location. But needs renovation and maintain, not even the lift was working, windows are cracking and the pool was half empty…. A pity"
Spain
Monica
The price is ¥12,253
¥13,479 total
includes taxes & fees
Nov 4 - Nov 5
Hotel Izan Trujillo

5. Eurostars Palacio Santa Marta

Eurostars Palacio Santa Marta
4.0 star property
Trujillo
9.2 out of 10, Wonderful, (361 reviews)
"Excelente location"
United Kingdom
Elizabeth
The price is ¥10,443
¥11,488 total
includes taxes & fees
Nov 5 - Nov 6
Eurostars Palacio Santa Marta

6. Plaza Sandra

Plaza Sandra
3.0 star property
Trujillo
9.6 out of 10, Exceptional, (59 reviews)
"Good staff and beautiful place "
United States
Juan
The price is ¥9,019
¥9,921 total
includes taxes & fees
Nov 9 - Nov 10
Plaza Sandra

7. Finca la Desa

Finca la Desa
3.0 star property
Miajadas
10.0 out of 10, Exceptional, (20 reviews)
"Beautiful place! Staff was amazing and is a worth visiting"
Spain
Ana
The price is ¥9,832
¥10,815 total
includes taxes & fees
Nov 4 - Nov 5
Finca la Desa

8. Hostal Hueso

Hostal Hueso
2.0 star property
Trujillo
8.2 out of 10, Very good, (26 reviews)
"Excelent location, excelent staf"
United States
ALFRED
The price is ¥10,443
¥11,487 total
includes taxes & fees
Nov 4 - Nov 5
Hostal Hueso

9. Hostal León

Hostal León
2.0 star property
Trujillo
7.6 out of 10, Good, (55 reviews)
"We turned up. No-one there ... Got to speak to a lady. Agreed to cancel with no charge. Expedia took the money anyway."
United Kingdom
Gareth
The price is ¥8,836
¥9,720 total
includes taxes & fees
Nov 4 - Nov 5
Hostal León

10. Alojamientos Plaza Mayor

Alojamientos Plaza Mayor
3.0 star property
Trujillo
8.0 out of 10, Very good, (56 reviews)
"Susana was very friendly and wait for us to give us the keys. Great location in front of main plaza. Basic room, very clean. Room was located in third floor, no elevator. Overall very good experience "
United States
Adela
The price is ¥6,367
¥7,003 total
includes taxes & fees
Nov 17 - Nov 18
Alojamientos Plaza Mayor

11. Hospedium Hotel Triana

Hospedium Hotel Triana
3.0 star property
Miajadas
8.0 out of 10, Very good, (24 reviews)
"This is a very convenient stop-over between Santander and Barbate/Vejer/Conil where we were staying. Simple, clean room,super helpful staff and great food at an amazing price. Free car parking in a plot next to the hotel. We've stayed here before and will do so again."
United Kingdom
tina
The price is ¥12,514
¥13,765 total
includes taxes & fees
Nov 10 - Nov 11
Hospedium Hotel Triana

12. Hostal Ruralis Altozano

Hostal Ruralis Altozano
1.0 star property
Montánchez
8.8 out of 10, Excellent, (3 reviews)
"La habitación estaba limpia y era cómoda, la ducha pequeña, y el personal agradable, la entrada fue sencilla y el pueblo es precioso. El hostal está en el centro del pueblo, pero las habitaciones que dan a la fachada principal si es fin de semana hay jaleo fuera y no hay quien duerma hasta tarde."
Spain
María Loreto
The price is ¥6,918
¥7,610 total
includes taxes & fees
Nov 5 - Nov 6
Hostal Ruralis Altozano
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels recommended for families in Santa Cruz de la Sierra

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Learn more about Santa Cruz de la Sierra

Head to Plaza Mayor and Pizarro House Museum—just two of the sights around Santa Cruz de la Sierra.

A large brick church with two bell towers and palm trees in front.

Top Santa Cruz de la Sierra Hotel Reviews

More cheap stays in Santa Cruz de la Sierra

Frequently asked questions

What's the best place to stay in Santa Cruz de la Sierra?
Hotel Izan Trujillo, located 0.1 mi (0.1 km) from the heart of Santa Cruz de la Sierra, is a top choice for your stay based on our traveler data. Other good options for your stay in the area are Eurostars Palacio Santa Marta and Parador de Trujillo. See all available top hotels, or vacation rentals in Santa Cruz de la Sierra.
What's the top vacation rental in Santa Cruz de la Sierra?
Rural house with swimming pool El Huerto del Olivo, Plasenzuela, Trujillo, Cáceres: This vacation home near Santa Cruz de la Sierra is equipped with a barbecue grill, air-conditioning, and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a dishwasher, a stovetop, and a microwave. See all vacation rentals in Santa Cruz de la Sierra.
If I need to cancel my hotel reservation in Santa Cruz de la Sierra, will I receive a refund?
Yes! Most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz de la Sierra.
Where can I learn more about changing or cancelling my trip to Santa Cruz de la Sierra?
To find more details about updating your trip to Santa Cruz de la Sierra or cancelling it, head over to our customer service page.
What are some accommodations with pools in Santa Cruz de la Sierra?
Hotel Izan Trujillo: Offers complimentary wired internet access, a seasonal outdoor pool, and LED televisions. Another choice that features an onsite pool is Rural house (full rental) El Olivar del Marqués for 26 people. View all hotels with pools in Santa Cruz de la Sierra.
What's the best accommodation near Adolfo Suarez Madrid-Barajas Airport (MAD)?
Madrid Marriott Auditorium Hotel & Conference Center is a popular 4-star hotel featuring 2 restaurants and 2 bars. It's located a short 1.4 mi (2.2 km) from Adolfo Suarez Madrid-Barajas Airport. Other accommodations close to the airport are Hotel Clement Barajas and Meliá Barajas.
What's it like to stay in Santa Cruz de la Sierra?
Those traveling to Santa Cruz de la Sierra are sure to enjoy the sights to see and things to do. In Santa Cruz de la Sierra, there are 9 hotels and other accommodations to choose from. Find out more about Santa Cruz de la Sierra.
What is there to see in Santa Cruz de la Sierra?
Places to visit in the wider area include Plaza Mayor, Pizarro House Museum, and Trujillo Castle. You'll also find Museo de Vino y Queso and Juan Pizarro de Orellana Palace in the area. Check out what more to see and do in Expedia's Santa Cruz de la Sierra guide.
What's the seasonal weather like in Santa Cruz de la Sierra?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 47°F. Average annual precipitation for Santa Cruz de la Sierra is 22 inches.