Find hotels in Santa Cecilia, Arequipa

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 23 - Dec 24
Tomorrow
Dec 24 - Dec 25
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Cecilia hotels

Standard Twin Room | Minibar, individually furnished, desk, free WiFi
Hotel TerraMistica Monasterio

Hotel TerraMistica Monasterio

Hotel TerraMistica Monasterio
3.0 star property
José Luis Bustamante y Rivero, 3.2 km from Santa Cecilia
10.0 out of 10, Exceptional, (1)
"Excelente ubicacion"
Mexico
Carlos
The price is ￥7,222
￥7,222 total
Dec 26 - Dec 27
Hotel TerraMistica Monasterio
In-room safe, free WiFi
Gatsby by HC Hoteles

Gatsby by HC Hoteles

Gatsby by HC Hoteles
3.0 star property
Historical Center, 1.8 km from Santa Cecilia
7.0 out of 10, Good, (16)
"The room was clean and cozy, sheets fresh and crisp. Great location a quick walk from many attractions. Hot shower. Safe, quiet and comfortable. "
Canada
shawn
The price is ￥6,315
￥6,315 total
Dec 24 - Dec 25
Gatsby by HC Hoteles
Classic Double Room | In-room safe, desk, laptop workspace, free WiFi
HUB HOTELS

HUB HOTELS

HUB HOTELS
3.0 star property
0.8 km from Santa Cecilia
10.0 out of 10, Exceptional, (2)
"The room and bathroom were spotless. The staff make a great breakfast, were also very friendly and even lent me a phone charger for a couple of hours. The area is safe, walkable and there are some stores and restaurants nearby. "
United States
Joel
The price is ￥10,199
￥10,199 total
Dec 25 - Dec 26
HUB HOTELS
Free daily continental breakfast
Casona Moya

Casona Moya

Casona Moya
2.5 star property
Historical Center, 1.4 km from Santa Cecilia
9.2 out of 10, Wonderful, (44)
"Really nice hotel to stay the owners are super nice and the vintage peruvian vibe is great. Definitely recommend for anyone staying in Arequipa."
Sweden
Algot
The price is ￥2,824
￥2,824 total
Dec 31 - Jan 1, 2026
Casona Moya
Reception
SOUL GARDEN HOTEL

SOUL GARDEN HOTEL

SOUL GARDEN HOTEL
3.0 star property
1.5 km from Santa Cecilia
7.2 out of 10, Good, (13)
"Great place! "
United States
Jorge
The price is ￥3,409
￥3,409 total
Dec 24 - Dec 25
SOUL GARDEN HOTEL
Room service - dining
Los Leones Hotel Boutique

Los Leones Hotel Boutique

Los Leones Hotel Boutique
3.5 star property
Yanahuara, 1.3 km from Santa Cecilia
8.4 out of 10, Very Good, (11)
"Good breakfast and confortable. .."
United States
violeta
The price is ￥15,062
￥16,568 total
Dec 24 - Dec 25
Los Leones Hotel Boutique
Hallway
Hoteles Riviera - Mansión

Hoteles Riviera - Mansión

Hoteles Riviera - Mansión
3.0 star property
Historical Center, 1.4 km from Santa Cecilia
7.6 out of 10, Good, (17)
"Leider war das Zimmer (Junior Suite) nicht sauber. Zwar war das Personal stehts um Sauberkeit bemüht, hat aber nicht geholfen. Eigentlich schade, da ich von den Riviera Hotels was anderes gewohnt bin. Und ja, leider stimmt es, wenn man ein Zimmer zur Strassenseite hat ist der Lärm unerträglich. Leider geht der Lärm bis spät in die Nacht und beginnt schon ab 5 Uhr. Wenig Schlaf is da vorprogramiert. Meiner Ansicht nach sollte das Hotel darauf achten, das die Suiten nicht zur Strasse...
Germany
Alfredo
The price is ￥8,002
￥8,002 total
Jan 21 - Jan 22, 2026
Hoteles Riviera - Mansión
Standard Double Room | Free WiFi, bed sheets
La Casa de Tin Tin

La Casa de Tin Tin

La Casa de Tin Tin
2.5 star property
Vallecito, 1.9 km from Santa Cecilia
10.0 out of 10, Exceptional, (2)
"Owner speaks in English and great hospitality "
United States
Kenji
La Casa de Tin Tin
Property grounds
Hostal La Casa de Melgar

Hostal La Casa de Melgar

Hostal La Casa de Melgar
2.5 star property
Historical Center, 1.5 km from Santa Cecilia
8.8 out of 10, Excellent, (64)
"Staff were very friendly and hotel is only a few minutes walk to main area. Many places to eat nearby and cash exchange places. Hotel is beautiful "
United States
Anonymous traveler
Hostal La Casa de Melgar
Free daily English breakfast
MonteCristoHotel

MonteCristoHotel

MonteCristoHotel
3.0 star property
Historical Center, 1 km from Santa Cecilia
9.0 out of 10, Wonderful, (17)
"Alojamiento con buena relación calidad-precio en Arequipa y bien situado. El personal muy amable."
Spain
Carlos
MonteCristoHotel
Junior Suite, City View | In-room safe, desk, laptop workspace, free WiFi
HOTEL BOUTIQUE AREQUIPA VIVE

HOTEL BOUTIQUE AREQUIPA VIVE

HOTEL BOUTIQUE AREQUIPA VIVE
3.0 star property
Vallecito, 1.4 km from Santa Cecilia
10.0 out of 10, Exceptional, (1)
The price is ￥9,100
￥9,100 total
Dec 27 - Dec 28
HOTEL BOUTIQUE AREQUIPA VIVE
Reception
Alsacia Boutique Hotel

Alsacia Boutique Hotel

Alsacia Boutique Hotel
3.0 star property
Historical Center, 1.2 km from Santa Cecilia
10.0 out of 10, Exceptional, (2)
"Quase em frente ao mosteiro de Santa Catalina. A duas quadras da praça de armas. Quartos confortáveis, bom café da manhã e funcionários muito amáveis e prestativos "
Brazil
Wilson Afonso
The price is ￥8,928
￥8,928 total
Dec 27 - Dec 28
Alsacia Boutique Hotel
Courtyard
El Portal de San Lázaro

El Portal de San Lázaro

El Portal de San Lázaro
3.0 star property
San Lázaro, 1.4 km from Santa Cecilia
9.0 out of 10, Wonderful, (34)
"One night stay on the way to colca canyon. Hotel is in historic centre, 10min walk to plasa the armas. Even closer are some bars and restaurants with good music and food. Room was small but clean, breakfast excellent, staff helpful and pleasant. Perfect for several nights in arequipa. Recommended. a"
European Union
Goran
The price is ￥5,190
￥5,190 total
Dec 26 - Dec 27
El Portal de San Lázaro
Pool waterfall
La Maison d'Elise

La Maison d'Elise

La Maison d'Elise
3.0 star property
Yanahuara, 0.8 km from Santa Cecilia
8.4 out of 10, Very Good, (9)
"The service is excellent. The location is great, between downtown and Yanahuara. The staff kept it very clean and the food was great."
United States
Elisa
The price is ￥10,988
￥12,086 total
Dec 24 - Dec 25
La Maison d'Elise
Restaurant
Hostal Lirium

Hostal Lirium

Hostal Lirium
3.0 star property
Sachaca, 3.2 km from Santa Cecilia
10.0 out of 10, Exceptional, (1)
"Everything was fine. "
United States
Claudia
The price is ￥4,236
￥4,236 total
Dec 24 - Dec 25
Hostal Lirium
Breakfast, lunch and dinner served
Hotel Natura Inn

Hotel Natura Inn

Hotel Natura Inn
3.0 star property
Yanahuara, 0.7 km from Santa Cecilia
8.8 out of 10, Excellent, (14)
"Beautiful property, walkable distance to restaurants and main attraction. The staff was so kind."
United States
Renzo
The price is ￥8,849
￥8,849 total
Dec 25 - Dec 26
Hotel Natura Inn
Front of property
Hotel Boutique Selva Alegre

Hotel Boutique Selva Alegre

Hotel Boutique Selva Alegre
3.0 star property
Historical Center, 1.9 km from Santa Cecilia
8.0 out of 10, Very Good, (21)
"Everything OK"
United States
Luis
The price is ￥7,205
￥7,205 total
Dec 25 - Dec 26
Hotel Boutique Selva Alegre
Lobby sitting area
El Cabildo Hotel Arequipa

El Cabildo Hotel Arequipa

El Cabildo Hotel Arequipa
3.5 star property
Historical Center, 2 km from Santa Cecilia
7.8 out of 10, Good, (10)
"Excelente, tranquilo, seguro, cómodo, buen desayuno y luya amables en la atención."
Mexico
Jose
The price is ￥9,885
￥10,478 total
Jan 6 - Jan 7, 2026
El Cabildo Hotel Arequipa
Reception
La casa de Theo

La casa de Theo

La casa de Theo
2.0 star property
Historical Center, 1.7 km from Santa Cecilia
9.6 out of 10, Exceptional, (4)
"Safe property in a heart of an old town. Breakfast was very nice."
United Kingdom
Jakub
The price is ￥10,393
￥10,393 total
Dec 29 - Dec 30
La casa de Theo
Front of property
Las Mercedes Hostal Residencial

Las Mercedes Hostal Residencial

Las Mercedes Hostal Residencial
3.0 star property
Vallecito, 0.9 km from Santa Cecilia
8.8 out of 10, Excellent, (52)
"The service and care was beyond amazing and the courtyard is beautiful!"
United States
misael
The price is ￥4,658
￥5,138 total
Dec 29 - Dec 30
Las Mercedes Hostal Residencial
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Santa Cecilia

Find the best Santa Cecilia areas and neighborhoods for the activities you enjoy most.

Historical Center

Unique features of Historical Center include the mountain views and historic sites. Make a stop by Arequipa Plaza de Armas or Arequipa Cathedral while you're exploring the area.

José Luis Bustamante y Rivero

Though José Luis Bustamante y Rivero might not have many top sights, you can venture to the surrounding area to see attractions like Mall Aventura Porongoche and Parque Lambramani.

Yanahuara

While visiting Yanahuara, you might make a stop by sights like Yanahuara Plaza and Yanahuara Viewpoint.

Mariano Melgar

Check out nearby sights like Museo de Arte Contemporaneo Arequipa while you're spending some time in Mariano Melgar and the surrounding area.

Alto Selva Alegre

Though Alto Selva Alegre might not have many top sights, you can venture to the surrounding area to see attractions like Yanahuara Plaza and Santa Catalina Monastery.

Top Santa Cecilia Hotel Reviews

qema Arequipa

qema Arequipa

10/10 Excellent
"Bar was an ok selection, food came out pretty fast. Rooms were sanitized daily. Staff was very helpful and attentive to any needs. Can't give an opinion on Breakfast as I didn't have any during the stay."
Gianfranco 4-night trip
Posted 2 days ago
qema Arequipa

Frequently asked questions

What is Santa Cecilia like?
Travelers to the Santa Cecilia neighborhood in Arequipa will be sure to enjoy their stay.
If I need to cancel my hotel reservation in Santa Cecilia, will I receive a refund?
Yes! Most hotel reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then filter by "fully refundable" to review the best options available in Santa Cecilia.
Where can I learn more about changing or cancelling my trip to Santa Cecilia?
To find more details about rescheduling or cancelling your trip to Santa Cecilia, click here.
What can I see and do in this Arequipa neighborhood?
Monasterio de la Recoleta, Umacollo Stadium, and Yanahuara Viewpoint are just a few of the places to visit in and around Santa Cecilia. Yanahuara Plaza and Museo Arqueológico de la Universidad Católica de Santa María are also worth a visit when you're out sightseeing in Arequipa.