Default HTG hotel image

Hotels near San Diego Santa Fe Depot

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for San Diego Santa Fe Depot hotels

Keating Hotel By At Mine Hospitality

Keating Hotel By At Mine Hospitality
2.0 star property
East Village, 1.2 km from San Diego Santa Fe Depot
9.6 out of 10, Exceptional, (33 reviews)
"Great experience Awesome hotel to stay Clean and comfortable beds Love the bath I would 100% recommend this hotel Thank you I will eventually return"
United States
Javie Alejandro
The price is ¥6,730
¥20,245 total
includes taxes & fees
Jun 29 - Jun 30
Keating Hotel By At Mine Hospitality

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
1.9 km from San Diego Santa Fe Depot
9.8 out of 10, Exceptional, (163 reviews)
"Nice and very friendly staff was a great stay"
United States
Alexander
The price is ¥22,664
¥31,007 total
includes taxes & fees
Jul 1 - Jul 2
City24 Hotel Little Italy Mission Hills

Springhill Suites San Diego Downtown/Bayfront

Springhill Suites San Diego Downtown/Bayfront
3.5 star property
0.2 km from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (1,002 reviews)
"We loved staying here! Amazing location, great breakfast options, rooms were nice and the view was amazing"
United States
Colleen
The price is ¥34,488
¥40,053 total
includes taxes & fees
Jul 6 - Jul 7
Springhill Suites San Diego Downtown/Bayfront

Stay Classy Hostel

Stay Classy Hostel
2.0 star property
East Village, 1.8 km from San Diego Santa Fe Depot
9.6 out of 10, Exceptional, (870 reviews)
"Great staff, check in was super easy and upon walking inside the building I felt super welcomed and its very clean and super comfortable"
United States
Miguel
The price is ¥9,176
¥10,438 total
includes taxes & fees
Jun 25 - Jun 26
Stay Classy Hostel

Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
1.1 km from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (1,110 reviews)
"Great stay! Big room, comfortable"
United States
Christine
The price is ¥31,224
¥36,203 total
includes taxes & fees
Jun 29 - Jun 30
Marriott Vacation Club®, San Diego

Hotel Z

Hotel Z
3.0 star property
Gaslamp Quarter, 1.1 km from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (1,005 reviews)
"Nice location"
United States
Rebecca
The price is ¥21,687
¥30,722 total
includes taxes & fees
Jun 29 - Jun 30
Hotel Z

Residence Inn by Marriott San Diego Downtown/Bayfront

Residence Inn by Marriott San Diego Downtown/Bayfront
3.0 star property
0.2 km from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (675 reviews)
"Loved how close it was to all the local things I wanted to do."
United States
Alexander
The price is ¥39,469
¥45,819 total
includes taxes & fees
Jul 6 - Jul 7
Residence Inn by Marriott San Diego Downtown/Bayfront

Westgate Hotel

Westgate Hotel
4.5 star property
0.6 km from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (1,000 reviews)
"Excellent hotel"
United States
Laurence
The price is ¥25,254
¥34,860 total
includes taxes & fees
Jun 28 - Jun 29
Westgate Hotel

Granger Hotel Gaslamp Quarter, A Member Of Design Hotels

Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
4.0 star property
Gaslamp Quarter, 0.8 km from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (762 reviews)
"The room was so clean, perfect amount of space for a short stay and the bar was nice addition. The stag is super nice and attentive.overall amazing stay."
United States
Ela
The price is ¥28,713
¥33,291 total
includes taxes & fees
Jun 28 - Jun 29
Granger Hotel Gaslamp Quarter, A Member Of Design Hotels

The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel

The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel
4.0 star property
0.1 km from San Diego Santa Fe Depot
9.0 out of 10, Wonderful, (1,179 reviews)
"It was very convenient for us, clean and comfortable"
United States
Diana
The price is ¥28,713
¥33,291 total
includes taxes & fees
Jun 28 - Jun 29
The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to San Diego Santa Fe Depot

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Superior Room, 1 King Bed, Private Bathroom, City View (Self check-in) | Desk, laptop workspace, blackout drapes, iron/ironing board
Keating Hotel By At Mine Hospitality
2.0 star property
9.6
Exceptional
33 reviews
View
Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio
City24 Hotel Little Italy Mission Hills
4.5 star property
9.8
Exceptional
163 reviews
View
Restaurant
Springhill Suites San Diego Downtown/Bayfront
3.5 star property
9.2
Wonderful
1,002 reviews
View
Memory foam beds, blackout drapes, iron/ironing board, free WiFi
Stay Classy Hostel
2.0 star property
9.6
Exceptional
870 reviews
View
Exterior
Marriott Vacation Club®, San Diego
3.5 star property
9.4
Exceptional
1,110 reviews
View

Top San Diego Santa Fe Depot Hotel Reviews

Find out more about San Diego Santa Fe Depot

San Diego Santa Fe Depot hotels information

Number of reviews
7,799
Accommodation
3,887 hotels
Lowest Price
¥10,438
Highest Price
¥45,819

Frequently asked questions

What's the area like around San Diego Santa Fe Depot?

San Diego Santa Fe Depot is located in a scenic area of San Diego known for its array of dining options and popular zoo. If you're looking for a convenient place to stay, check out the 847 hotels and other accommodations located within a mile of the station.

What's the best hotel to stay close to San Diego Santa Fe Depot?

Adjacent to San Diego Santa Fe Depot, The Sofia Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and a 24-hour fitness center. Other good options close by include Manchester Grand Hyatt San Diego and Wyndham San Diego Bayside.

How many hotels will I find close to San Diego Santa Fe Depot?

Expedia has 847 hotels and other accommodations within a mile from the station.

What can I see and do near San Diego Santa Fe Depot?

Study the collections at USS Midway Museum, Maritime Museum of San Diego, or San Diego Air and Space Museum. Hotel del Coronado, Whaley House Museum, and Spreckels Theater are monuments to see when you're exploring the area around San Diego Santa Fe Depot. You can watch performances at San Diego Civic Theatre, The Rady Shell at Jacobs Park, and Humphreys Concerts by the Bay if you're interested in local theater.