What is Ruta Independencia like?

You'll be sure to have fun visiting Oaxaca's Ruta Independencia neighborhood. Be sure to check out Oaxaca Ethnobotanical Garden and Jardín Etnobotánico as part of your Ruta Independencia travel plans.

Where is the best place to stay in Ruta Independencia?

Based on our traveler data, Quinta Real Oaxaca is one of the top choices for your stay in Ruta Independencia. This hotel is steps from Church of Santo Domingo de Guzmán, and offers a restaurant and an outdoor pool. Other good choices for your stay in the neighborhood include Grand Fiesta Americana Oaxaca and Holiday Inn Express Oaxaca-Centro Historico by IHG .

How many hotels will I find in the Ruta Independencia area?

Expedia has 336 hotels and other accommodations in Ruta Independencia to choose from, making this an ideal home base for exploring the greater Oaxaca area.

If I need to cancel my hotel reservation in Ruta Independencia, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable if you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to review the best options available in Ruta Independencia.

Where can I learn more about changing or cancelling my trip to Ruta Independencia?

For more information about changing or cancelling your trip to Ruta Independencia, click here .

What is there to do around this Oaxaca neighborhood?

Explore Ruta Independencia's landmarks like Church of Santo Domingo de Guzmán, Andador de Macedonia Alcala, and Museo de las Culturas de Oaxaca and learn about the local history. Oaxaca Ethnobotanical Garden and Jardín Etnobotánico are also a couple of places to visit in the neighborhood. A few places to visit in the area around Ruta Independencia include Museo Filatelia (MUFI), Museum of Oaxacan Culture, and Quetzalli Gallery. While you're out sightseeing, Panuelito Garden and Graphic Arts Institute of Oaxaca are a couple of additional sights to visit in Oaxaca.

Top Ruta Independencia Hotels

A cactus garden with tall cacti and a reflective pond.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Ruta Independencia hotels

A hotel room with two beds, a desk, a television, and a minibar.

1. Holiday Inn Express Oaxaca-Centro Historico by IHG

Ruta Independencia

JAIME

￥20,414 total

includes taxes & fees

Oct 11 - Oct 12

A spacious lobby with a wooden bench, red chairs, and a glass coffee table.

2. Hotel Abu

Ruta Independencia

Leandro

￥19,413 total

includes taxes & fees

Sep 24 - Sep 25

A clear blue swimming pool with a tiled edge, a lounge area with chairs, and a view of distant mountains.

3. Hotel Parador de Alcalá Oaxaca

Ruta Independencia

Daniel

￥20,398 total

includes taxes & fees

Sep 27 - Sep 28

An outdoor patio area with tables and chairs, string lights, and a view of the surrounding landscape.

4. Casa de los Frailes Hotel

Ruta Independencia

Ariadna

￥12,376 total

includes taxes & fees

Sep 28 - Sep 29

An indoor courtyard with a tiled floor, tables, chairs, and potted plants.

5. Casa Vertiz

Ruta Independencia

Jessenia

￥30,196 total

includes taxes & fees

Sep 28 - Sep 29

A courtyard with a central building featuring a dome and arches, surrounded by stone buildings.

6. Quinta Real Oaxaca

Ruta Independencia

William

￥58,413 total

includes taxes & fees

Oct 18 - Oct 19

A modern living room with a sofa, a painting, and a bed in the background.

7. Hotel Casa del Sótano

Ruta Independencia

Peter

￥20,251 total

includes taxes & fees

Sep 24 - Sep 25

A corridor with a wooden ceiling, potted plants, and a seating area.

8. Hotel Casa Antigua

Ruta Independencia

Elda

￥23,964 total

includes taxes & fees

Sep 30 - Oct 1

A courtyard with a stone staircase leading to a dining area with a round table and chairs.

9. Eco Hotel Las Mariposas

Ruta Independencia

Rafal

￥11,046 total

includes taxes & fees

Oct 22 - Oct 23

A modern building with a prominent 'One' sign, potted plants, and a curved entrance.

10. One Oaxaca Centro Hotel

Ruta Independencia

Jorge

￥13,104 total

includes taxes & fees

Oct 6 - Oct 7

A courtyard with a table and chairs under a large umbrella, surrounded by potted plants and a red brick building.

11. Parador Del Dominico

Ruta Independencia

Lorena

￥12,735 total

includes taxes & fees

Sep 28 - Sep 29

A corridor with arched ceilings and wall-mounted lights, leading to a balcony with a railing.

12. Hotel Casa Conzatti

Ruta Independencia

Nancy

￥18,409 total

includes taxes & fees

Sep 24 - Sep 25

A covered corridor with tiled flooring, wooden benches, and potted plants.

13. NaNa Vida Hotel Oaxaca

Ruta Independencia

Jeremiah

￥22,654 total

includes taxes & fees

Oct 1 - Oct 2

A modern indoor water feature with a circular design, a small pool, and a waterfall.

14. Grand Fiesta Americana Oaxaca

Ruta Independencia

Jasmine

￥56,152 total

includes taxes & fees

Oct 6 - Oct 7

A room with a blue door, a desk, a chair, and a potted plant.

15. Un sueno Valle de Huajes

Ruta Independencia

William

￥8,023 total

includes taxes & fees

Sep 24 - Sep 25

A hallway with a tiled floor, a plant, a table with a lamp, and a vase.

16. Hotel Don Nino

Ruta Independencia

Anna

￥9,683 total

includes taxes & fees

Sep 24 - Sep 25

An outdoor pool area with a curved edge, surrounded by palm trees and plants, and a yellow building with a wrought iron gate in the background.

17. Hotel Oaxaca Real

Ruta Independencia

JACQUELINE

￥18,371 total

includes taxes & fees

Oct 22 - Oct 23

A multi-level courtyard with outdoor seating areas, a pool, and a mix of architectural styles including arches and columns.

18. Hotel CasAntica

Ruta Independencia

Juan Carlos

￥17,434 total

includes taxes & fees

Sep 24 - Sep 25

A modern building with large windows, potted plants, and a bench.

19. Majagua Hotel Boutique Adults Only

Ruta Independencia

Ana

￥38,916 total

includes taxes & fees

Sep 28 - Sep 29

20. Hotel Casa Santo Tomás

Ruta Independencia

Jerilyn

￥10,238 total

includes taxes & fees

Sep 24 - Sep 25

View all properties

Compare popular hotels in Ruta Independencia

Property	Star rating	Guest rating
REFORMA 516	2.0 star property	9.8 Exceptional 14 reviews	View
NaNa Vida Hotel Oaxaca	3.5 star property	9.8 Exceptional 832 reviews	View
Casa Naila Hotel Boutique	3.5 star property	9.8 Exceptional 27 reviews	View
Casa Sofi Oaxaca	2.0 star property	9.8 Exceptional 31 reviews	View
Grana B&B	3.0 star property	9.8 Exceptional 124 reviews	View

Where to stay in Ruta Independencia

Find the best Ruta Independencia areas and neighborhoods for the activities you enjoy most. Learn more about Ruta Independencia

A historic cathedral with two prominent towers and a large dome.

Oaxaca Centro

Discover colonial-era structures and immerse in native Zapotec and Mixtec cultures in this UNESCO World Heritage Site. Explore the archeological marvel of Monte Albán and admire the unique green stone architecture.

See properties

A narrow cobblestone street flanked by colorful buildings with balconies and hanging plants.

Jalatlaco

While Jalatlaco isn't home to many top sights, El Llano Park and Oaxaca Ethnobotanical Garden are some notable places to visit nearby.

See properties

A colorful sign with the letters "OAKLA" in a public square with a fountain and statues in the background.

Reforma

If you're spending some time in Reforma, Plaza Parque and Plaza Mazari are top sights worth seeing.

See properties

Ancient ruins with stone walls and a grassy field, set against a mountainous backdrop.

Santa Cruz Xoxocotlán

Visitors to Santa Cruz Xoxocotlán like its archaeological sites and cafes, and Monte Albán is a sight worth a stop.

See properties

A person with arms raised, a colorful hot air balloon, and ancient ruins in the background.

Santa Lucía del Camino

When in Santa Lucía del Camino, you can plan a visit to Oaxaca Cultural and Convention Center and El Llano Park, some noteworthy sights in the nearby area.

See properties

Top Ruta Independencia Hotel Reviews

Luuna de Jade

10/10 Excellent

"Everything was fantastic, the property is in an excellent location for exploring Oaxaca City without a car. Even though our room was great, I should point out that the King Bed was too short for someone over 6' 2" tall. I would also like to see a microwave oven and cream for the espresso coffee. Despite these caveats, the room was excellent and the bed comfortable. My wife loves the shower and the water pressure was outstanding...... Tacos Roy is only a few steps away from the front door. Panaderia La Luna has good pan dulces and pastries for a low price. Ixu Cat Cafe is 3 blocks East if you love kitties..... Service is outstanding and they really go an extra mile to make your stay comfortable!"

One Oaxaca Centro Hotel

10/10 Excellent

"Excelente hotel muy comodo, limpio y sobre todo muy centrico en el mero centro a unas varias cuadras de todo.... Los unicos PEROS que le pongo son por cosas menores como que las habitaciones son pequenas pero yo se que asi son las cadenas de ONE en todas partes... y queel desayuno es 2-3 nada espectacular pero no decepcionada y que la ubicacion de GPS de hotels esta incorrecta me hizo perder mucho tiempo buscando el hotel... de ahi en mas todo excelente y el personal super amable nos trataron muy bien. Sin duda alguna me volveria a quedar ahi."

Lar Syrah

8/10 Good

"Lar Sahyr is in a great location for exploring the old town and surrounding neighborhoods. Hotel is very clean and well presented and the room was a great size and very comfortable. Some minor issues day one with accessing the hotel using code and with shower temp but onsite and virtual staff very responsive and helpful."

City Express by Marriott Oaxaca

10/10 Excellent

"My sisters, cousins and I stayed here in August 2026 for a girls trip and had a wonderful experience. A huge highlight was the breakfast buffet which was fresh and had plenty of options. The location is perfect a few minutes from Downtown and surrounded by good local restaurants."

Find hotels in Ruta Independencia, Oaxaca

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Ruta Independencia hotels

1. Holiday Inn Express Oaxaca-Centro Historico by IHG

2. Hotel Abu

3. Hotel Parador de Alcalá Oaxaca

4. Casa de los Frailes Hotel

5. Casa Vertiz

6. Quinta Real Oaxaca

7. Hotel Casa del Sótano

8. Hotel Casa Antigua

9. Eco Hotel Las Mariposas

10. One Oaxaca Centro Hotel

11. Parador Del Dominico

12. Hotel Casa Conzatti

13. NaNa Vida Hotel Oaxaca

14. Grand Fiesta Americana Oaxaca

15. Un sueno Valle de Huajes

16. Hotel Don Nino

17. Hotel Oaxaca Real

18. Hotel CasAntica

19. Majagua Hotel Boutique Adults Only

20. Hotel Casa Santo Tomás

Compare popular hotels in Ruta Independencia

Where to stay in Ruta Independencia

Oaxaca Centro

Jalatlaco

Reforma

Santa Cruz Xoxocotlán

Santa Lucía del Camino

Top Ruta Independencia Hotel Reviews

Luuna de Jade

Frequently asked questions

Explore a world of travel with Expedia