Photo by Bill Eaker

Find Luxury Hotels in Muscatine, IA

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Muscatine Luxury Hotels

Tonight
Jul 27 - Jul 28
Tomorrow
Jul 28 - Jul 29
Next weekend
Aug 1 - Aug 3
In two weeks
Aug 8 - Aug 10

Top Muscatine Luxury Hotels

Super 8 by Wyndham Muscatine
Free daily on-the-go breakfast

Super 8 by Wyndham Muscatine

2.0 star property
6.2 out of 10, (272)
"Everything was great!"
The price is ￥9,415
￥10,545 total
includes taxes & fees
Jul 28 - Jul 29
Super 8 by Wyndham Muscatine
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Muscatine Hotel Reviews

DoubleTree by Hilton Davenport

DoubleTree by Hilton Davenport

10/10 Excellent
"Parking was off-site but reasonably priced."
Jonathan 1-night trip
Posted 2 days ago
DoubleTree by Hilton Davenport

Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Muscatine?
Use Expedia to help you arrange a flight to Quad City Intl. Airport (MLI) airport, and then choose from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to get what you'd like to make your stay relaxing and comfortable. If you want an upscale hotel with fine dining, a spa, or several swimming pools, Expedia can help you find the best luxury hotel experience that Muscatine has to offer. Muscatine has some interesting things to see and do including Mississippi River and Riverside Park, so you might want to take in the local sights during your visit.
What's the best luxury hotel in Muscatine?
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel is a 4-star hotel with a terrace and a bar, and it's a popular choice for Expedia travelers looking for an elegant place to stay.
How many luxury hotels should I expect to find in Muscatine?
Lie in the lap of luxury during your getaway to Muscatine in one of Expedia's 6 luxury hotels.
When can I expect good weather in Muscatine?
Planning for the weather is an important factor for making your trip to Muscatine a success, especially when you're splurging. The hottest months are usually July and August with an average temp of 72°F, while the coldest months are January and February with an average of 30°F. The snowiest months in Muscatine are January, November, February, and December, with each month seeing an average of 7 inches of snowfall.
What's there to see and do in Muscatine?
Enjoy Muscatine with a stop at Mississippi River, Riverside Park, and Wildcat Den State Park. If you have spare time during your trip, you might want to make a stop at Cedar River and Muscatine Art Center.