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Our top choices for Mesilla vacation homes

1. Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian

Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian
Mesilla
10.0 out of 10, Exceptional, (99 reviews)
"Outstanding. Will definitely stay again."
United States
Glenn N.
The price is ¥19,205
¥41,991 total
includes taxes & fees
Nov 12 - Nov 13
Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian

2. Charming 2-bedroom Casita In Mesilla Park Casita Conway #5

Charming 2-bedroom Casita In Mesilla Park Casita Conway #5
Las Cruces
10.0 out of 10, Exceptional, (14 reviews)
"This casita is beautiful, welcoming, and comfortable! Everything was perfect for our family of 5. Everything was clean, beds were comfortable, air conditioning was awesome. We had such a wonderful stay! I would definitely stay again if we are in the area again. Thank you for your hospitality."
United States
Tiffany
The price is ¥12,571
¥26,013 total
includes taxes & fees
Nov 16 - Nov 17
Charming 2-bedroom Casita In Mesilla Park Casita Conway #5

3. Unique 1-bedroom casita in Mesilla Park with hot tub

Unique 1-bedroom casita in Mesilla Park with hot tub
Las Cruces
9.8 out of 10, Exceptional, (31 reviews)
"Super cute casita. Small but perfect for me and my husband. Could easily be room enough for 4! Hot tub was great and easy to use. Bed was super comfy. House was clean and well decorated. Private porch was lovely! Parking was right out front. 10/10 great stay"
United States
Reagan L.
The price is ¥14,221
¥24,321 total
includes taxes & fees
Nov 15 - Nov 16
Unique 1-bedroom casita in Mesilla Park with hot tub

4. 2 bed, yard, pet friendly in Historic Mesilla.

2 bed, yard, pet friendly in Historic Mesilla.
Las Cruces
10.0 out of 10, Exceptional, (3 reviews)
"We liked the location and homey feeling. Nice to have a yard and chiminea, though we didn't use it this trip."
United States
Tom K.
The price is ¥17,459
¥47,032 total
includes taxes & fees
Nov 15 - Nov 16
2 bed, yard, pet friendly in Historic Mesilla.

5. Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces Casita Conway 2

Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces Casita Conway 2
Las Cruces
9.2 out of 10, Wonderful, (20 reviews)
"Such a cute place, very clean and comfortable. We really enjoyed our visit. Would definitely stay there again!"
United States
Reina R.
The price is ¥11,904
¥24,430 total
includes taxes & fees
Nov 14 - Nov 15
Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces Casita Conway 2

6. 3 bed 2 bath Hacienda near Downtown and NMSU.

3 bed 2 bath Hacienda near Downtown and NMSU.
Las Cruces
10.0 out of 10, Exceptional, (1 review)
"Such an adorable place to stay! We stopped through for one night on our way to our destination. The beds were comfortable and the house was so unique. We loved the fresh eggs for breakfast!"
United States
Sarah E.
The price is ¥16,983
¥55,631 total
includes taxes & fees
Nov 15 - Nov 16
3 bed 2 bath Hacienda near Downtown and NMSU.

7. Modern New Mexico Loft in the heart of Las Cruces.

Modern New Mexico Loft in the heart of Las Cruces.
Las Cruces
The price is ¥11,904
¥37,604 total
includes taxes & fees
Nov 12 - Nov 13
Modern New Mexico Loft in the heart of Las Cruces.

8. Step into a newly renovated two-bed, one-bath haven in Mesilla Casita Conway #4

Step into a newly renovated two-bed, one-bath haven in Mesilla Casita Conway #4
Las Cruces
10.0 out of 10, Exceptional, (11 reviews)
"Lovely Casita, close to everything, yet has a country feel."
United States
Anonymous traveler
The price is ¥13,491
¥27,011 total
includes taxes & fees
Nov 18 - Nov 19
Step into a newly renovated two-bed, one-bath haven in Mesilla Casita Conway #4

9. 1 bedroom near NMSU. W/D in unit/pets welcome.

1 bedroom near NMSU. W/D in unit/pets welcome.
Las Cruces
10.0 out of 10, Exceptional, (2 reviews)
"This property was a perfect stop over for a couple of nights. What made it so perfect is that we could bring our fur babies with us. We especially appreciated the fenced in back yard. The house itself had all the modern conveniences of home. The fresh eggs and muffins were a wonderful surprise."
United States
Debbie B.
The price is ¥15,078
¥34,908 total
includes taxes & fees
Nov 15 - Nov 16
1 bedroom near NMSU. W/D in unit/pets welcome.

10. 2 bed with W/D, pets ok, 5 min to Farmers Market

2 bed with W/D, pets ok, 5 min to Farmers Market
Las Cruces
8.0 out of 10, Very good, (1 review)
"Was a bit difficult to get into the house on first. Told the key pad numbers but didn't tell us to press KWIKSET. Then, to go leave, we didn't know that we just press KWICKSET. It would have been hpful to know all of that in the initial email. In addition, the key pad is at the front door NOT the back door. "
United States
Elaine
The price is ¥15,011
¥42,655 total
includes taxes & fees
Nov 27 - Nov 28
2 bed with W/D, pets ok, 5 min to Farmers Market

11. Historical 1920s Bungalow Near NMSU & Mesilla

Historical 1920s Bungalow Near NMSU & Mesilla
Las Cruces
10.0 out of 10, Exceptional, (1 review)
"Very clean house and communication with Celeste was good had no problem checking in. Parking on property was great secure and plenty of space. Will definitely be booking again in the future"
United States
Braulio H.
The price is ¥19,046
¥37,161 total
includes taxes & fees
Nov 15 - Nov 16
Historical 1920s Bungalow Near NMSU & Mesilla

12. Cozy and Modern Home w/ King Bed and more!

Cozy and Modern Home w/ King Bed and more!
Las Cruces
9.8 out of 10, Exceptional, (31 reviews)
"We only stayed for a short visit but we had a great time. The Casita is deceptively big with plenty of room to relax. Comfy bed. The Wifi is excellent, too!"
United States
Megan H.
The price is ¥11,904
¥40,215 total
includes taxes & fees
Nov 17 - Nov 18
Cozy and Modern Home w/ King Bed and more!

13. The New Zen Den- Cozy Private Studio with Kitchenette & Private Entrance

The New Zen Den- Cozy Private Studio with Kitchenette & Private Entrance
Las Cruces
10.0 out of 10, Exceptional, (3 reviews)
"Good location and comfortable spot. Worked out well for our stay."
United States
Sara L.
The price is ¥11,377
¥19,526 total
includes taxes & fees
Nov 22 - Nov 23
The New Zen Den- Cozy Private Studio with Kitchenette & Private Entrance

14. Casita! Fully functional kitchen and bathroom!

Casita! Fully functional kitchen and bathroom!
Las Cruces
9.8 out of 10, Exceptional, (11 reviews)
"Everything was excellent. Shopping was nearby which made it convenient. Communication was great"
United States
Sue M.
Casita! Fully functional kitchen and bathroom!

15. 2 king bds/2.5 bathrooms in the heart of Downtown

2 king bds/2.5 bathrooms in the heart of Downtown
Las Cruces
10.0 out of 10, Exceptional, (1 review)
"Great communication with host, perfect location centrally located, quiet neighborhood. Beautiful home!"
United States
Veronica M.
The price is ¥17,777
¥58,608 total
includes taxes & fees
Nov 15 - Nov 16
2 king bds/2.5 bathrooms in the heart of Downtown

16. 2 bd/2bth near NMSU and Memorial Medical Center

2 bd/2bth near NMSU and Memorial Medical Center
Las Cruces
10.0 out of 10, Exceptional, (4 reviews)
"Delightful and felt welcome there. All as promoted and responses were totally on point. Location is comforting as well."
United States
Wendy W.
The price is ¥16,824
¥50,527 total
includes taxes & fees
Nov 15 - Nov 16
2 bd/2bth near NMSU and Memorial Medical Center

17. Rock House Retreat, Hot Tub, 2min to Downtown

Rock House Retreat, Hot Tub, 2min to Downtown
Las Cruces
10.0 out of 10, Exceptional, (1 review)
"Perfect spot for my friends and I the night before Dangerbird!"
United States
Alexander M.
The price is ¥15,043
¥26,281 total
includes taxes & fees
Nov 12 - Nov 13
Rock House Retreat, Hot Tub, 2min to Downtown

18. 2 bd w/lrg fenced yard 3 mins from farmers market

2 bd w/lrg fenced yard 3 mins from farmers market
Las Cruces
10.0 out of 10, Exceptional, (2 reviews)
"Excellent little house with an amazing back yard!! This house has been completely refurbished with new furniture and appliances! If you’re looking for something with southwest style, you’ll appreciate the tile work in the kitchen and decorations throughout. The neighborhood has lots of culture with art and murals on walls and buildings. Make sure to go to the park nearby and visit The Bean coffee shop (got a red chile latte) and La Nueva Casita Café for a good local New Mexican meal. "
United States
Angelina M.
The price is ¥16,824
¥46,294 total
includes taxes & fees
Nov 15 - Nov 16
2 bd w/lrg fenced yard 3 mins from farmers market

19. Payne Place 1

Payne Place 1
Las Cruces
9.4 out of 10, Exceptional, (3 reviews)
"Clean, clean and clean! Great communication "
United States
Diana P.
The price is ¥15,801
¥36,995 total
includes taxes & fees
Nov 12 - Nov 13
Payne Place 1

20. 2 bed/2 bath quiet neighborhood

2 bed/2 bath quiet neighborhood
Las Cruces
10.0 out of 10, Exceptional, (1 review)
"Cute little clean townhome in a quiet neighborhood."
United States
Anthony J.
The price is ¥14,285
¥33,703 total
includes taxes & fees
Nov 22 - Nov 23
2 bed/2 bath quiet neighborhood
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Mesilla

Historic adobe buildings surround the plaza where Billy the Kid once stood trial in this charming town. Explore local art galleries and sample authentic Mexican cuisine at La Posta, a restaurant housed in a 19th-century stagecoach stop.

A rustic building with a wooden door, a hanging red chili, and a cactus plant.

Top reviews in Mesilla