Find Resorts & Hotels with Spas in Megalochori

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Our top choices for Megalochori hotels with a spa

Summer Lovers Villa

Summer Lovers Villa
Santorini
9.6 out of 10, Exceptional, (18)
"We booked the entire villa for our family and even exchanged our vows on the property—it was truly magical. Miss Marita was amazing, taking care of us in every possible way. We couldn’t have been happier with our stay and hope to return soon. If you’re looking for a private, unforgettable family getaway, I highly recommend Summer Lovers Villa."
United States
zuzana
The price is ¥20,371
¥23,225 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Summer Lovers Villa

Ira Hotel & Spa - Adults Only

Ira Hotel & Spa - Adults Only
4.0 star property
Santorini
9.4 out of 10, Exceptional, (1001)
"Cleaning service provided daily, all hotel staff was very kind and professional. "
United States
EBONY
The price is ¥15,520
¥18,176 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Ira Hotel & Spa - Adults Only

Elements Cave Suites

Elements Cave Suites
Santorini
9.2 out of 10, Wonderful, (16)
"Lovely place to stay in a quiet area that still has great restaurants and some shops around. "
United Kingdom
Kyle Schulz
The price is ¥10,649
¥12,185 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Elements Cave Suites

Suites of the Gods Cave Spa

Suites of the Gods Cave Spa
5.0 star property
Santorini
8.6 out of 10, Excellent, (293)
"From check-in to check-out, everything felt smooth and welcoming. We would happily stay here again and would recommend it to anyone looking for a comfortable and pleasant stay."
Canada
LADONNA
Suites of the Gods Cave Spa

Above Blue Suites

Above Blue Suites
Santorini
9.6 out of 10, Exceptional, (308)
"Beautiful location, nice spacious room."
Canada
Victor
The price is ¥16,142
¥18,424 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Above Blue Suites

Irigeneia Hotel

Irigeneia Hotel
4.0 star property
Santorini
9.4 out of 10, Exceptional, (137)
"Excellent location, very comfortable rooms, clean with nice view. Delicious breakfast and an excellent service, here you have the privilege to be attended by the owners, they a magnificent job."
United States
Wilson
The price is ¥10,023
¥11,934 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Irigeneia Hotel

The Noverian Bios Santorini

The Noverian Bios Santorini
Santorini
9.2 out of 10, Wonderful, (9)
"Seriously have nothing but amazing things to say about our stay here!! The room was perfect and very clean. There was free water, slippers, and coffee each day for us. Helena was so attentive and kind - making sure everything was perfect each day + giving so many options for beach clubs and excursions in Santorini. The location was very walkable and close to the bus station + downtown Fira. Breakfast delivered to the room was such a treat. I would recommend this hotel to absolutely anyone...
United States
Maraci
The price is ¥8,763
¥10,226 total
includes taxes & fees
Jan 5 - Jan 6, 2026
The Noverian Bios Santorini

De Sol Spa Hotel

De Sol Spa Hotel
5.0 star property
Santorini
9.4 out of 10, Exceptional, (526)
"The rooms were clean and the service outstanding. "
United States
Teresa
The price is ¥28,131
¥32,681 total
includes taxes & fees
Jan 1 - Jan 2, 2026
De Sol Spa Hotel

Astro Palace Hotel & Spa

Astro Palace Hotel & Spa
5.0 star property
Santorini
9.2 out of 10, Wonderful, (741)
"Liked the Hotel location, 200 m to downtown, beautiful rooms and lobby and good spa. "
United States
Behroze
Astro Palace Hotel & Spa

Athina Luxury Suites

Athina Luxury Suites
Santorini
9.4 out of 10, Exceptional, (479)
"Clean rooms and very helpful and welcoming staff "
United States
Sima
The price is ¥30,397
¥34,613 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Athina Luxury Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Megalochori Hotel Reviews

Frequently asked questions

Looking for a spa hotel in Megalochori?
Book one of our wonderful spa hotels and treat yourself from the moment you arrive. Check out the beaches in Megalochori - worth a picture or two! Be sure to enjoy the wineries during your stay. Hotels with spas are the perfect way to break out of your daily routine and add a layer of luxury to your vacation.
What is the best spa hotel in Megalochori?
May Seven Santorini is a top spa hotel with 6 rooms, free WiFi, and concierge services. Treat yourself to a massage at the on-site spa. Other popular spa hotels in Megalochori include Enarma Suites & Spa Wellness Retreat and Vedema, a Luxury Collection Resort, Santorini.
How many spa hotels will I find in Megalochori?
Among Expedia's 136 accommodation options in Megalochori, there are 5 spa hotels.
What's there to see and do in Megalochori?
Enjoy all that Megalochori has to offer when you visit Santorini Caldera, Gavalas Vineyard, and Boutari Winery. If you have some spare time during your trip, you might want to check out Athinios Port and Santo Wines.
What is a Megalochori spa hotel?
Spa hotels in Megalochori provide lodging and have an on-site spa offering services like couples massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.