Photo by Caroline Nunez

Mayesville Vacation Rentals

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 15 - Dec 16
Tomorrow
Dec 16 - Dec 17
This weekend
Dec 19 - Dec 21
Next weekend
Dec 26 - Dec 28

Our top choices for Mayesville vacation rentals

Fridge, microwave, oven, stovetop
Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly

Vacation Home in Rembert

Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly
9.6 out of 10, Exceptional, (24)
"Would definitely stay here again! This property is very reasonably priced. Host was great in communication. It was just a lovely, peaceful, and safe place to stay! Wish we would have stayed longer! Thank you so very much."
United States
Josh M.
The price is ￥18,931
￥33,420 total
includes taxes & fees
Dec 16 - Dec 17
Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly
Dining
Charming 3-bedroom house in wonderful Sumter

Vacation Home in Sumter

Charming 3-bedroom house in wonderful Sumter
2.0 star property
8.4 out of 10, Very Good, (21)
"Cozy home in a very quiet neighborhood close to shopping great location "
United States
John J.
Charming 3-bedroom house in wonderful Sumter
Smart TV
3 bedroom home located within a mile from downtown

Vacation Home in Sumter

3 bedroom home located within a mile from downtown
8.0 out of 10, Very Good, (11)
"I booked the property then second guessed it but I was surprised when I checked in. I will definitely book again when visiting family "
United States
Dwayne
3 bedroom home located within a mile from downtown
Fridge, microwave, oven, stovetop
Remodeled home with firepit and only 9 minutes from downtown area!

Vacation Home in Sumter

Remodeled home with firepit and only 9 minutes from downtown area!
9.6 out of 10, Exceptional, (17)
"Will definitely stay again"
United States
James H.
Remodeled home with firepit and only 9 minutes from downtown area!
Fridge, microwave, oven, stovetop
Creekside Country Cottage- minutes away from I-95

Cottage in Manning

Creekside Country Cottage- minutes away from I-95
10.0 out of 10, Exceptional, (9)
"Great place beautiful and the dogs loved it"
United States
Jennifer T.
The price is ￥35,057
￥67,796 total
includes taxes & fees
Dec 16 - Dec 17
Creekside Country Cottage- minutes away from I-95
Fridge, microwave, oven, stovetop
Cozy comfortable home near lakes, parks and downtown Sumter

Vacation Home in Sumter

Cozy comfortable home near lakes, parks and downtown Sumter
10.0 out of 10, Exceptional, (51)
"The property is excellently kept. Comfortable, inviting, and spacious We very much enjoyed our time there. "
United States
Carmen B.
Cozy comfortable home near lakes, parks and downtown Sumter
Interior
Relaxing 3-Bedroom Getaway in Peaceful Cades – Sleeps 8

Vacation Home in Cades

Relaxing 3-Bedroom Getaway in Peaceful Cades – Sleeps 8
Relaxing 3-Bedroom Getaway in Peaceful Cades – Sleeps 8
Fridge, microwave, oven, stovetop
Charming 4-bedroom house with WiFi near Shaw Airforce and Downtown Sumter

Vacation Home in Sumter

Charming 4-bedroom house with WiFi near Shaw Airforce and Downtown Sumter
10.0 out of 10, Exceptional, (1)
"Clean, beautiful home in a safe neighborhood. Beds were comfy and kitchen and bathrooms were properly equipped. We would definitely book again."
United States
Sonya J.
Charming 4-bedroom house with WiFi near Shaw Airforce and Downtown Sumter
Dining
The Farm House on Adams

Vacation Home in Sumter

The Farm House on Adams
The price is ￥28,046
￥55,843 total
includes taxes & fees
Jan 2 - Jan 3, 2026
The Farm House on Adams
House (3 Bedrooms) | Interior
Quiet & Cozy Rembert Home ~ 9 Mi to Air Force Base

Cottage in Rembert

Quiet & Cozy Rembert Home ~ 9 Mi to Air Force Base
3.0 star property
Quiet & Cozy Rembert Home ~ 9 Mi to Air Force Base
Exterior
The Moise Manor, a 1934 Bungalow, centrally located in the heart of Sumter.

Vacation Home in Sumter

The Moise Manor, a 1934 Bungalow, centrally located in the heart of Sumter.
10.0 out of 10, Exceptional, (3)
"We loved the property. It was family friendly and baby proof. We loved the accommodations. It fit the whole family and we had plenty space. The customer service was amazing."
United States
Melissa P.
The Moise Manor, a 1934 Bungalow, centrally located in the heart of Sumter.
Fridge, microwave, oven, dishwasher
Modern & Spacious Duplex

Vacation Home in Sumter

Modern & Spacious Duplex
10.0 out of 10, Exceptional, (1)
"My family and I really enjoyed our time here. Shaun and Beth are great hosts. They were very responsive to our needs and have good accommodations. I would definitely stay here again."
United States
Elronzo W.
Modern & Spacious Duplex
Smart TV
Carriage House near parks, walking paths, and historic downtown Sumter!

Apartment in Sumter

Carriage House near parks, walking paths, and historic downtown Sumter!
2.0 out of 10, (1)
"Stood in 100 degree heat just to check in"
United States
pat W.
Carriage House near parks, walking paths, and historic downtown Sumter!
Interior
Home away from home

Vacation Home in Dalzell

Home away from home
9.0 out of 10, Wonderful, (2)
"This property is exactly as described. It was immaculate, spacious and comfortable. The kitchen is well stocked with everything you could need. Great water pressure in the showers and updated appliances. The owner was immediately responsive to any questions. 10/10 would recommend and rent again. "
United States
Stacy G.
Home away from home
House (3 Bedrooms) | Interior
Sumter Vacation Rental in Historic District!

Cottage in Sumter

Sumter Vacation Rental in Historic District!
3.0 star property
Sumter Vacation Rental in Historic District!
House (4 Bedrooms) | Interior
'vibe Villa' w/ Backyard ~ 8 Mi to Shaw Afb!

Cottage in Sumter

'vibe Villa' w/ Backyard ~ 8 Mi to Shaw Afb!
3.0 star property
'vibe Villa' w/ Backyard ~ 8 Mi to Shaw Afb!
Private kitchen
Charming 1-bedroom house with WiFi, AC in nice Sumter

Vacation Home in Sumter

Charming 1-bedroom house with WiFi, AC in nice Sumter
The price is ￥15,581
￥29,841 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Charming 1-bedroom house with WiFi, AC in nice Sumter
Apartment (0 Bedroom) | Interior
Backyard Oasis w/ Pool: Sunny Sumter Studio!

Apartment in Sumter

Backyard Oasis w/ Pool: Sunny Sumter Studio!
3.0 star property
Backyard Oasis w/ Pool: Sunny Sumter Studio!
Fridge, microwave, oven, stovetop
White House on Winn

Vacation Home in Sumter

White House on Winn
10.0 out of 10, Exceptional, (5)
"The property was very nice, clean, and quiet. We had no issues and enjoyed our stay."
United States
Jana I.
White House on Winn
Dining
Rapsody among Nature Perfect 1-bedroom Guest house in Sumter for your getaway

Vacation Home in Sumter

Rapsody among Nature Perfect 1-bedroom Guest house in Sumter for your getaway
2.0 star property
Rapsody among Nature Perfect 1-bedroom Guest house in Sumter for your getaway
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Mayesville Hotel Reviews

1912 Bed and Breakfast

1912 Bed and Breakfast

10/10 Excellent
"Good "
Ronald 3-night trip
Posted 18 hours ago
1912 Bed and Breakfast

Find out more about Mayesville

Search for holiday rentals in Mayesville on Expedia! You can easily find your home rentals, villas, holiday apartments in Mayesville using one of the methods below:

  • View our selection of featured holiday rentals in Mayesville
  • Use the map to find apartments and other holiday homes in the Mayesville neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Mayesville while they last

Look no further and take a look at our great range of rental properties in Mayesville!

Frequently asked questions

Can I find a vacation rental in Mayesville?

Yes, we give you a choice of vacation rentals near well known sights in Mayesville, or you can choose a more remote option if you'd like a relaxing place to stay.

What are some of the best vacation rentals that Mayesville has to offer?

Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly : Visitors like this Mayesville vacation home rental. It is located in a rural location and has an outdoor pool, a fireplace, and air-conditioning to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. Kick off your shoes and enjoy yourself with a patio and a selection of games.

What can I see and do in Mayesville?

While you're exploring the area, Riley Field and Palmetto Park are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Morris College and O'Donnell House.

What are vacation rentals like in Mayesville?

Vacation rentals are private accommodations you can reserve for a short or long stay in Mayesville. Vacation rentals offer extras such as laundry facilities and kitchens so you'll feel right at home. If you're concerned about a sanitized environment, vacation rentals can provide a sense of privacy away from public hotel elevators and busy concierge desks while still allowing you to travel. You'll also get more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a great option for families.