Find hotels in Mackenzie, St. Louis from ￥16,144

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Dec 12 - Dec 13
Tomorrow
Dec 13 - Dec 14
This weekend
Dec 12 - Dec 14
Next weekend
Dec 19 - Dec 21

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Our top choices for Mackenzie hotels

Breakfast, lunch and dinner served
Live by Loews - St.Louis

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis, 11.7 km from Mackenzie
9.4 out of 10, Exceptional, (1096)
"Great staff"
United States
Phillip
The price is ￥23,168
￥27,554 total
includes taxes & fees
Dec 14 - Dec 15
Live by Loews - St.Louis
Seasonal outdoor pool
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
25.5 km from Mackenzie
8.4 out of 10, Very Good, (1004)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is ￥23,658
￥30,228 total
includes taxes & fees
Dec 14 - Dec 15
Ameristar Casino Resort and Spa
Lobby
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 12.3 km from Mackenzie
8.4 out of 10, Very Good, (4003)
"Arch view room is big and comfortable fantastic. . "
United States
Tim
The price is ￥13,855
￥16,340 total
includes taxes & fees
Dec 21 - Dec 22
Hyatt Regency St. Louis at The Arch
Property amenity
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 12.1 km from Mackenzie
9.4 out of 10, Exceptional, (3275)
"Our stay was very enjoyable. Location was great and kids loved the indoor pool!"
United States
Christy
The price is ￥20,990
￥24,543 total
includes taxes & fees
Dec 16 - Dec 17
Drury Plaza Hotel St. Louis at the Arch
Property amenity
Moonrise Hotel

Moonrise Hotel

Moonrise Hotel
4.0 star property
8.4 km from Mackenzie
9.0 out of 10, Wonderful, (1912)
"Great service, unique hotel. Would absolutely stay again!"
United States
Michael
The price is ￥17,742
￥21,101 total
includes taxes & fees
Dec 13 - Dec 14
Moonrise Hotel
Terrace/patio
Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
5.5 km from Mackenzie
9.4 out of 10, Exceptional, (833)
"We always enjoy our stay here nice clean and great location "
United States
Dominique
The price is ￥15,728
￥19,295 total
includes taxes & fees
Dec 14 - Dec 15
Courtyard by Marriott St. Louis Brentwood
Lobby
Pear Tree Inn St. Louis Convention Center

Pear Tree Inn St. Louis Convention Center

Pear Tree Inn St. Louis Convention Center
3.0 star property
Downtown St. Louis, 12.5 km from Mackenzie
9.0 out of 10, Wonderful, (1051)
"It was perfect for our stay in St. Louis to visit the arch."
United States
Jacob
The price is ￥14,615
￥17,089 total
includes taxes & fees
Dec 17 - Dec 18
Pear Tree Inn St. Louis Convention Center
Exterior
Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 12.3 km from Mackenzie
8.8 out of 10, Excellent, (1242)
"Great hospitality"
United States
Alejandro
The price is ￥16,669
￥19,825 total
includes taxes & fees
Dec 18 - Dec 19
Embassy Suites by Hilton St. Louis Downtown
Indoor pool, open 6:00 AM to 10:00 PM, sun loungers
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
2.5 star property
Downtown St. Louis, 12.5 km from Mackenzie
8.6 out of 10, Excellent, (1164)
"The room was clean and the staff were extremely friendly and personable! "
United States
Shannon
The price is ￥14,802
￥17,308 total
includes taxes & fees
Dec 18 - Dec 19
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Lobby
St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West, 10.9 km from Mackenzie
8.4 out of 10, Very Good, (1006)
"Nice historic hotel"
United States
Michelle
The price is ￥22,058
￥26,233 total
includes taxes & fees
Dec 21 - Dec 22
St. Louis Union Station Hotel, Curio Collection by Hilton
Bar (on property)
Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield
3.0 star property
22.7 km from Mackenzie
9.6 out of 10, Exceptional, (1000)
"Very clean, friendly staff and great breakfast options "
United States
Angela
The price is ￥19,164
￥22,227 total
includes taxes & fees
Dec 14 - Dec 15
Hyatt Place St. Louis/Chesterfield
Bar (on property)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis, 12.1 km from Mackenzie
8.8 out of 10, Excellent, (1148)
"Really nice hotel!"
United States
DARIN
The price is ￥13,575
￥16,144 total
includes taxes & fees
Dec 16 - Dec 17
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Front of property
Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis, 12.3 km from Mackenzie
8.8 out of 10, Excellent, (1014)
"My second time staying there as always it was lovely "
United States
Nina
The price is ￥16,047
￥18,924 total
includes taxes & fees
Dec 20 - Dec 21
Hilton Pennywell St. Louis at the Arch
Restaurant
21C Museum Hotel St Louis

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West, 11.4 km from Mackenzie
9.0 out of 10, Wonderful, (1492)
"Room was perfect and parking was a breeze. We really enjoyed the art was wonderful. "
United States
London
The price is ￥20,851
￥25,159 total
includes taxes & fees
Dec 18 - Dec 19
21C Museum Hotel St Louis
Courtyard
The Knight Center at Washington University

The Knight Center at Washington University

The Knight Center at Washington University
2.5 star property
7.7 km from Mackenzie
9.4 out of 10, Exceptional, (441)
"The hotel is beautiful and the staff is very helpful and kind. "
United States
Beth
The price is ￥18,709
￥21,514 total
includes taxes & fees
Jan 1 - Jan 2, 2026
The Knight Center at Washington University
Gastropub
The Cheshire

The Cheshire

The Cheshire
4.0 star property
5.9 km from Mackenzie
8.6 out of 10, Excellent, (1003)
"Excellent place to stay. "
United States
Todd
The price is ￥19,747
￥23,446 total
includes taxes & fees
Dec 17 - Dec 18
The Cheshire
Terrace/patio
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
9.9 km from Mackenzie
8.8 out of 10, Excellent, (1034)
"Fun staff and a very cool hotel. Great room, too!"
United States
Christopher
The price is ￥18,534
￥21,857 total
includes taxes & fees
Dec 17 - Dec 18
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Lobby
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
26.5 km from Mackenzie
8.8 out of 10, Excellent, (1013)
"I Loved it I would definitely stay there again"
United States
Roberta
The price is ￥18,534
￥21,301 total
includes taxes & fees
Dec 21 - Dec 22
Embassy Suites by Hilton St. Louis St. Charles
Front of property - evening/night
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
3.5 star property
23.9 km from Mackenzie
8.4 out of 10, Very Good, (2217)
"Front staff was very friendly and very helpful. Check-in and check out was smooth and very easy. "
United States
James
The price is ￥16,325
￥21,305 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Hollywood Casino & Hotel St. Louis
Lobby
Missouri Athletic Club

Missouri Athletic Club

Missouri Athletic Club
3.5 star property
Downtown St. Louis, 12.5 km from Mackenzie
8.8 out of 10, Excellent, (1000)
"The room was nice and the staff was excellent."
United States
Annette
The price is ￥23,125
￥27,040 total
includes taxes & fees
Dec 14 - Dec 15
Missouri Athletic Club
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Mackenzie

Find the best Mackenzie areas and neighborhoods for the activities you enjoy most.
Meeting of the Waters Fountain showing a statue or sculpture and a fountain

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Central West End

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Top Mackenzie Hotel Reviews

21C Museum Hotel St Louis

21C Museum Hotel St Louis

10/10 Excellent
"The hotel is beautiful! It was a great pick for so much to do on the property. From the pool area with hot tub and saunas . To the art gallery, and the stubbing bar! Grab some fantastic cocktails! Ask for Sunday, she was wonderful bartending! Perfect stay."
Ashton 2-night trip
Posted 8 hours ago
21C Museum Hotel St Louis

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Frequently asked questions

What's it like in Mackenzie?
Travelers will be sure to find plenty to entertain them in St. Louis's Mackenzie neighborhood.
If I need to cancel my hotel reservation in Mackenzie, will I receive a refund?
Yes! Most hotel bookings are fully refundable if cancelled before the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer in Mackenzie.
Where can I learn more about changing or cancelling my trip to Mackenzie?
To access more information about changing or cancelling your trip to Mackenzie, go to https://www.expedia.com/service/.
What is there to do in this St. Louis neighborhood?
Lindenwood Park, Repertory Theatre of St. Louis, and River des Peres Greenway Trailhead are just a few of the places to visit in and around Mackenzie. While you're out sightseeing, The Focal Point and Webster Groves Tennis Center are a couple of additional sights to visit in St. Louis.