Top Mackenzie Hotels

A gazebo with a green roof, surrounded by a pond, with red and green foliage in the background.

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Our top choices for Mackenzie hotels

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

1. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 6.2 km from Mackenzie

Jennifer

￥25,704 total

includes taxes & fees

Oct 4 - Oct 5

A modern hotel lobby with a reception desk, seating area, and a refreshment bar.

2. SpringHill Suites St. Louis Brentwood

4.9 km from Mackenzie

Cheryl

￥21,412 total

includes taxes & fees

Oct 11 - Oct 12

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

3. Wingate by Wyndham St. Louis Airport

18.2 km from Mackenzie

Mary

￥17,315 total

includes taxes & fees

Sep 28 - Sep 29

A lobby with a reception desk, seating area, and a bicycle in the background.

4. Drury Inn & Suites St. Louis Forest Park

4.7 km from Mackenzie

Robert

￥27,400 total

includes taxes & fees

Oct 4 - Oct 5

An outdoor patio with a fire pit, seating, and a building in the background.

5. Courtyard by Marriott St. Louis Brentwood

5.5 km from Mackenzie

Aaron

￥21,878 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with a minibar, a shoe rack, a coat rack, and a TV.

6. Holiday Inn Express & Suites St. Louis South - I-55 by IHG

11.2 km from Mackenzie

Thomas

￥22,607 total

includes taxes & fees

Oct 4 - Oct 5

The Clayton Plaza Hotel sign with a stone wall and plants in front.

7. Clayton Plaza Hotel & Extended Stay

7.8 km from Mackenzie

Sivakumar

￥16,865 total

includes taxes & fees

Oct 11 - Oct 12

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

8. Pear Tree Inn St. Louis Airport

18.2 km from Mackenzie

Monica

￥16,665 total

includes taxes & fees

Oct 4 - Oct 5

A swimming pool with a metal ladder, surrounded by chairs and large windows offering a view of the sunset.

9. La Quinta Inn & Suites by Wyndham St Louis Route 66

8.3 km from Mackenzie

Crystal

￥19,424 total

includes taxes & fees

Oct 25 - Oct 26

A rooftop terrace with wicker furniture, offering a city view.

10. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis, 12.1 km from Mackenzie

Salvatore

￥24,826 total

includes taxes & fees

Oct 2 - Oct 3

A modern interior with hanging pendant lights, large windows, and a view of the outside.

11. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

13.8 km from Mackenzie

Dashaun

￥17,137 total

includes taxes & fees

Sep 28 - Sep 29

A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.

12. River City Casino & Hotel

7.3 km from Mackenzie

Ashley

￥18,705 total

includes taxes & fees

Oct 11 - Oct 12

A cozy lounge area with leather sofas, a fireplace, and a bar counter.

13. The Cheshire

5.9 km from Mackenzie

Matthew

￥27,717 total

includes taxes & fees

Oct 11 - Oct 12

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

14. Drury Plaza Hotel St. Louis Brentwood

5.8 km from Mackenzie

Janell

￥25,394 total

includes taxes & fees

Oct 4 - Oct 5

A spacious lobby with a high ceiling, modern lighting fixtures, a seating area with sofas and chairs, and a bar area with stools.

15. Hampton Inn & Suites St. Louis/South I-55

11.2 km from Mackenzie

Shannon

￥19,132 total

includes taxes & fees

Oct 4 - Oct 5

A rooftop restaurant with round tables, chairs, and a view of the city.

16. Moonrise Hotel

8.4 km from Mackenzie

Nicole

￥24,689 total

includes taxes & fees

Sep 29 - Sep 30

An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

17. Home2 Suites by Hilton St. Louis/Forest Park

The Grove, 7.4 km from Mackenzie

paullita jeanne

￥28,594 total

includes taxes & fees

Oct 4 - Oct 5

A modern lobby with a stone fireplace, blue sofas, and potted plants.

18. Comfort Suites St. Louis - Sunset Hills

8.4 km from Mackenzie

John

￥21,600 total

includes taxes & fees

Oct 4 - Oct 5

A modern outdoor lounge area with seating, a bar, and a view of a cityscape.

19. Live by Loews - St.Louis

Downtown St. Louis, 11.7 km from Mackenzie

Frank

￥29,741 total

includes taxes & fees

Oct 4 - Oct 5

A modern living area with a sofa, armchairs, a coffee table, and a kitchen in the background.

20. Best Western St. Louis Inn

13.9 km from Mackenzie

Harold

￥14,324 total

includes taxes & fees

Oct 4 - Oct 5

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Where to stay in Mackenzie

Find the best Mackenzie areas and neighborhoods for the activities you enjoy most.

The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch National Park or Kiener Plaza might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

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A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

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A fountain in front of a red brick building with green roofs and white trim.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

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A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

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A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

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Top Mackenzie Hotel Reviews

Clayton Plaza Hotel & Extended Stay

10/10 Excellent

"We loved our stay. Everything was clean and the bed was the most comfortable hotel bed I’ve slept on. We had a blast. The breakfast was delicious."

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent

"Well located near the Arch National Park; was able to leave our car at the hotel garage and walk to the Arch. Make sure you check-in before 5:00 or so, so that you can take advantage of their happy hour which features THREE FREE DRINKS and pretty good appetizers. Monday was pulled pork sliders and chili/nachos. Staff was very helpful and attentive. Great place to stay if you’re visiting the Arch."

Live by Loews - St.Louis

10/10 Excellent

"Wonderful stay. Comfy bed. One of cleanest rooms I’ve ever stayed in. It is convenient to Busch Stadium, but just a heads up that if you stay there, any of the events may be cause for a bit of noise - but with the television on, it just sounded like any metropolitan area. Would not hesitate to stay again."

Frequently asked questions

What's it like in Mackenzie?

Travelers will be sure to find plenty to entertain them in St. Louis's Mackenzie neighborhood.

If I need to cancel my hotel reservation in Mackenzie, will I receive a refund?

Yes! Most hotel bookings are fully refundable if cancelled before the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer in Mackenzie.

Where can I learn more about changing or cancelling my trip to Mackenzie?

To access more information about changing or cancelling your trip to Mackenzie, go to https://www.expedia.com/service/.

What is there to do in this St. Louis neighborhood?

Lindenwood Park, Repertory Theatre of St. Louis, and River des Peres Greenway Trailhead are just a few of the places to visit in and around Mackenzie. While you're out sightseeing, The Focal Point and Webster Groves Tennis Center are a couple of additional sights to visit in St. Louis.

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Our top choices for Mackenzie hotels

1. Hampton Inn & Suites St. Louis at Forest Park

2. SpringHill Suites St. Louis Brentwood

3. Wingate by Wyndham St. Louis Airport

4. Drury Inn & Suites St. Louis Forest Park

5. Courtyard by Marriott St. Louis Brentwood

6. Holiday Inn Express & Suites St. Louis South - I-55 by IHG

7. Clayton Plaza Hotel & Extended Stay

8. Pear Tree Inn St. Louis Airport

9. La Quinta Inn & Suites by Wyndham St Louis Route 66

10. Drury Plaza Hotel St. Louis at the Arch

11. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

12. River City Casino & Hotel

13. The Cheshire

14. Drury Plaza Hotel St. Louis Brentwood

15. Hampton Inn & Suites St. Louis/South I-55

16. Moonrise Hotel

17. Home2 Suites by Hilton St. Louis/Forest Park

18. Comfort Suites St. Louis - Sunset Hills

19. Live by Loews - St.Louis

20. Best Western St. Louis Inn

Where to stay in Mackenzie

Downtown St. Louis

Clayton

Central West End

St. Charles Historic District

Creve Coeur

Top Mackenzie Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Frequently asked questions

Explore a world of travel with Expedia