Find Resorts & Hotels with Spas in Louisville, KY

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Check availability on Louisville Resorts & Hotels with Spas

Tonight
Dec 21 - Dec 22
Tomorrow
Dec 22 - Dec 23
Next weekend
Dec 26 - Dec 28
In two weeks
Jan 2 - Jan 4

Our top choices for Louisville hotels with a spa

4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (3893)
"Great place to stay! "
United States
Rochelle
The price is ￥21,028
￥24,742 total
includes taxes & fees
Dec 27 - Dec 28
Galt House Hotel Trademark Collection by Wyndham
Indoor pool
Caesars Southern Indiana - A Caesars Rewards Destination

Caesars Southern Indiana - A Caesars Rewards Destination

Caesars Southern Indiana - A Caesars Rewards Destination
3.5 star property
Elizabeth
8.2 out of 10, Very Good, (1001)
"The room was very clean, the staff was very friendly and helpful."
United States
Judy
The price is ￥14,041
￥18,739 total
includes taxes & fees
Dec 23 - Dec 24
Caesars Southern Indiana - A Caesars Rewards Destination
Sauna, body treatments, aromatherapy, hot stone massages
Omni Louisville Hotel

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1743)
"This is a beautiful hotel in a great location. Very kind staff and helpful with directions."
United States
Bonnie
The price is ￥26,376
￥31,034 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Omni Louisville Hotel
Full-size fridge, microwave, oven, stovetop
The Reserve on Main

The Reserve on Main

The Reserve on Main
4.0 star property
Downtown Louisville
10.0 out of 10, Exceptional, (1)
"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "
Canada
georgios
The price is ￥26,029
￥38,100 total
includes taxes & fees
Dec 28 - Dec 29
The Reserve on Main
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1004)
"Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!"
United States
Tammy
The price is ￥21,927
￥26,590 total
includes taxes & fees
Jan 1 - Jan 2, 2026
21c Museum Hotel Louisville
Exterior detail
Central Park Bed & Breakfast

Central Park Bed & Breakfast

Central Park Bed & Breakfast
4.0 star property
Old Louisville
9.4 out of 10, Exceptional, (56)
"Our stay here was excellent in every way! The owners were very sweet and went out of their way to assist us in every way, the rooms were very cozy, and the breakfasts were fantastic. This is the best B&B we've ever stayed."
United States
John
The price is ￥19,464
￥22,592 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Central Park Bed & Breakfast
Bar (on property)
Pillow and Paddock B&B

Pillow and Paddock B&B

Pillow and Paddock B&B
3.5 star property
La Grange
10.0 out of 10, Exceptional, (52)
"Great stay. Great hospitality"
United States
James
The price is ￥56,746
￥62,557 total
includes taxes & fees
Jan 22 - Jan 23, 2026
Pillow and Paddock B&B
Nightclub
Bourbon Manor B&B

Bourbon Manor B&B

Bourbon Manor B&B
4.0 star property
Bardstown
9.8 out of 10, Exceptional, (76)
"Clean room, friendly staff"
United States
Heather
Bourbon Manor B&B
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Louisville Hotel Reviews

Hawthorn Suites by Wyndham Louisville East

Hawthorn Suites by Wyndham Louisville East

10/10 Excellent
"Big nice room, friendly staff "
Kim 1-night trip
Posted 4 days ago
Hawthorn Suites by Wyndham Louisville East

Frequently asked questions

Looking for a spa hotel in Louisville?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travelers love the riverfront in Louisville. Be sure to pay a visit to the museums during your stay. Hotels with spas are the perfect way to break out of your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in Louisville?
Galt House Hotel Trademark Collection by Wyndham is a top spa hotel featuring 4 restaurants, a fitness center, a hair salon, and a bar. Spend an afternoon at the spa where you'll find deep-tissue massages, hot stone massages, and mani/pedis. In-room massages are also available. Other popular spa hotels in Louisville include Omni Louisville Hotel and 21c Museum Hotel Louisville.
How many spa hotels will I find in Louisville?
Among Expedia's 2227 accommodation options in Louisville, there are 5 spa hotels.
What's there to see and do in Louisville?
Experience Louisville and visit KFC Yum Center, Whiskey Row, and Belle of Louisville. If you have a little extra time during your trip, you might want to check out Riverfront Plaza Belvedere and Evan Williams Bourbon Experience.
What is a Louisville spa hotel?
Spa hotels in Louisville provide lodging and have an on-site spa which offers services including massages and body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.