A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

Find Resorts & Hotels with Spas in Key Largo, FL

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Check availability on Key Largo Resorts & Hotels with Spas

Tonight
Oct 19 - Oct 20
Tomorrow
Oct 20 - Oct 21
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Our top choices for Key Largo hotels with a spa

A hotel room with a bed, a dresser, a mirror, and a nightstand.
A beachfront property with a balcony overlooking the sea, palm trees, and a well-lit outdoor seating area.
A poolside area with blue chairs and a thatched-roof structure.
A beach with thatched umbrellas, palm trees, and blue lounge chairs.

1. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
  • Discover tranquil bliss at this waterfront haven with three spa rooms, private beach, and hot stone massages.
￥34,606
￥45,254 total
includes taxes & fees
Oct 22 - Oct 23
Reefhouse Resort & Marina
A modern living room with a wooden desk, a computer, and a sofa. There are two chairs and a lamp. The room has a patterned wall and a view of another room with a dining table.
A child sitting on a beach with sand toys and a green bucket nearby.
A balcony with white wicker furniture, a table, and a view of the sea.
A table with a glass pitcher, a glass with a slice of lime, and a plate with raspberries and a sprig of rosemary.

2. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
￥42,631
￥56,672 total
includes taxes & fees
Oct 28 - Oct 29
Baker's Cay Resort Key Largo, Curio Collection by Hilton
A spacious lobby with hanging chairs, a round wooden table with a starfish and a cactus, and a reception desk in the background.
A pool area with lounge chairs and umbrellas, a clear sky, and palm trees.
A beach with clear water, a wooden pier, and lounge chairs under a tree.
An aerial view of a resort with a large pool, palm trees, and a beach.

3. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Immerse in waterfront wellness at this bay resort with a full-service spa, offering daily Ayurvedic treatments and relaxing garden escapes.
￥44,088
￥58,311 total
includes taxes & fees
Nov 1 - Nov 2
Playa Largo Resort & Spa, Autograph Collection
A view through a window with metal bars, featuring a beach with palm trees, a thatched umbrella, and a wooden dock.
A tropical resort with a paved pathway leading to a building, surrounded by palm trees and lush greenery.
A clear blue pool surrounded by palm trees and a thatched-roof structure, with a sign indicating no diving.
A beachside resort with lounge chairs, a pool, and palm trees.

4. Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only
Rock Harbor
  • Serene spa getaway with tranquil gardens and sunset views from the oceanfront hot tub.
￥25,386
￥33,004 total
includes taxes & fees
Oct 20 - Oct 21
Kona Kai Resort and Gallery - Adults Only
A wooden table with two white cups, one with coffee and one with tea, placed on a body of water.
A room with a bed, two chairs, and a view of a lake.
A couple in a room with a large window overlooking the sea, a bed with pillows, a small table with a vase of flowers, and a plant.
A floating house with a thatched roof, large sliding glass doors, and a wooden deck with a chair.

5. Premium Floating Bungalow by Stay Ombi

Premium Floating Bungalow by Stay Ombi
Key Largo
  • Luxurious massages offered on spa-equipped houseboat with premium floating rooms and serene water access.
￥106,430
￥119,734 total
includes taxes & fees
Oct 21 - Oct 22
Premium Floating Bungalow by Stay Ombi
A conference room with a large painting of a blue ocean, two Laptops, and wicker chairs.
A tropical resort with a swimming pool, palm trees, and a waterfall.
A bar area with a thatched roof, wooden chairs, and a view of the ocean.
A bathroom with a large bathtub, a window with curtains, and a view of palm trees and the sea.

6. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Luxury spa sanctuary with 7 treatment rooms offers beachside massages and tranquil gardens for ultimate rejuvenation.
￥29,245
￥44,456 total
includes taxes & fees
Oct 22 - Oct 23
Cheeca Lodge & Spa
A hotel room with two beds, a large window with a view of a balcony, and a curtain on the window.
A balcony with a wooden table, two chairs, and a view of the ocean and palm trees.
A balcony with two wooden chairs and a small table, overlooking a beach with palm trees and the ocean.
A beachside patio with a thatched roof, two lounge chairs, and a view of the ocean.

7. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
  • Beachfront spa villa with two pools, massage services, and scenic water walkway offers rejuvenating Florida escape.
￥76,713
￥96,547 total
includes taxes & fees
Oct 29 - Oct 30
The Islands of Islamorada
View all properties

Choose what matters most at spa hotels in Key Largo

Pool
Hot tub
Breakfast included
Gym
5 stars

Top Key Largo Hotel Reviews

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"clean room and very unique location. The breakfast was just ok and overpriced"
Anna 1-night trip
Posted 5 hours ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Dove Creek Resort & Marina, Trademark Collection by Wyndham

Dove Creek Resort & Marina, Trademark Collection by Wyndham

10/10 Excellent
"Very beautiful place"
Gerard 3-night trip
Posted 5 hours ago
Dove Creek Resort & Marina, Trademark Collection by Wyndham
Reefhouse Resort & Marina

Reefhouse Resort & Marina

8/10 Good
"Room are a little dated but overall nice. Pool and beach area were well maintained. We got couples massages and those were great. Pricing for them was reasonable. We would come back again!"
Austin 3-night trip
Posted 2 days ago
Reefhouse Resort & Marina
Amoray Dive Resort

Amoray Dive Resort

10/10 Excellent
"Cute little place. Beautiful and convenient location near the state park and walkable to restaurants."
Kirsten 2-night trip
Posted 5 days ago
Amoray Dive Resort

Frequently asked questions

Looking for a spa hotel in Key Largo?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers love the sunsets in Key Largo. Discover the coral reefs and seafood restaurants during your stay. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a top beach spa hotel featuring 4 restaurants, 3 bars, a 24-hour fitness center, and a hair salon. Treat yourself to a facial, body scrub, or Swedish massage at the onsite spa. Another popular spa hotel in Key Largo is Reefhouse Resort & Marina.
How many spa hotels will I find in Key Largo?
Among Expedia's 1296 accommodation options in Key Largo, there are 2 spa hotels.
What's there to see and do in Key Largo?
Enjoy Key Largo and visit Jimmy Johnson's Big Chill, Jacob's Aquatic Center, and Bluefin Rock Harbor Marina. If you have a bit of extra time while you're in the area, you might want to check out John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.
What is a Key Largo spa hotel?
Spa hotels in Key Largo provide lodging and have an on-site spa offering services including facials and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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