A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

Find Resorts & Hotels with Spas in Key Largo, FL

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Check availability on Key Largo Resorts & Hotels with Spas

Tonight
Sep 4 - Sep 5
Tomorrow
Sep 5 - Sep 6
This weekend
Sep 4 - Sep 6
Next weekend
Sep 11 - Sep 13

Our top choices for Key Largo hotels with a spa

Breadfruit Suite | Terrace/patio
Exterior
Exterior
Exterior

1. Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only
Rock Harbor
  • Serene spa getaway with tranquil gardens and sunset views from the oceanfront hot tub.
￥20,933
￥27,940 total
includes taxes & fees
Sep 10 - Sep 11
Kona Kai Resort and Gallery - Adults Only
Spa treatment
Poolside bar
Beach
Bar (on property)

2. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
  • Discover tranquil bliss at this waterfront haven with three spa rooms, private beach, and hot stone massages.
￥34,186
￥44,704 total
includes taxes & fees
Sep 13 - Sep 14
Reefhouse Resort & Marina
Reception
Beach House, 3 Bedrooms, Pool Access, Bay View (Balcony/Patio, Private Pool) | Beach
Exterior
Pool

3. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Immerse in waterfront wellness at this bay resort with a full-service spa, offering daily Ayurvedic treatments and relaxing garden escapes.
￥39,806
￥53,387 total
includes taxes & fees
Sep 22 - Sep 23
Playa Largo Resort & Spa, Autograph Collection
In-room dining
Exterior
Exterior
Living area

4. Premium Floating Bungalow by Stay Ombi

Premium Floating Bungalow by Stay Ombi
Key Largo
  • Luxurious massages offered on spa-equipped houseboat with premium floating rooms and serene water access.
￥128,443
￥144,498 total
includes taxes & fees
Sep 8 - Sep 9
Premium Floating Bungalow by Stay Ombi
Lobby
Poolside bar
Balcony
Property grounds

5. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Luxury spa sanctuary with 7 treatment rooms offers beachside massages and tranquil gardens for ultimate rejuvenation.
￥23,658
￥38,228 total
includes taxes & fees
Sep 9 - Sep 10
Cheeca Lodge & Spa
Spa treatment
Terrace/patio
Breakfast meal
Living area

6. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
  • Beachfront spa villa with two pools, massage services, and scenic water walkway offers rejuvenating Florida escape.
￥61,323
￥78,818 total
includes taxes & fees
Sep 16 - Sep 17
The Islands of Islamorada
View all properties

Choose what matters most at spa hotels in Key Largo

Pool
Hot tub
Breakfast included
Gym
5 stars

Top Key Largo Hotel Reviews

Reefhouse Resort & Marina

Reefhouse Resort & Marina

10/10 Excellent
"Loved the property. Staff was great. Grounds relaxing. Will go back."
Yvonne 3-night trip
Posted 16 hours ago
Reefhouse Resort & Marina
Amoray Dive Resort

Amoray Dive Resort

10/10 Excellent
"This property was clean and the staff was very friendly. It is a cozy little get away in Key Largo with nice restaurants close by. Would definitely stay again."
P 2-night trip
Posted 2 days ago
Amoray Dive Resort
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

10/10 Excellent
"Perfection!"
Lauren 3-night trip
Posted 3 days ago
Playa Largo Resort & Spa, Autograph Collection

Frequently asked questions

Looking for a spa hotel in Key Largo?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers love the sunsets in Key Largo. Discover the coral reefs and seafood restaurants during your stay. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a top beach spa hotel featuring 3 restaurants, a 24-hour fitness center, a hair salon, and a bar. Treat yourself to a facial, body scrub, or Swedish massage at the onsite spa. Another popular spa hotel in Key Largo is Reefhouse Resort & Marina.
How many spa hotels will I find in Key Largo?
Among Expedia's 1324 accommodation options in Key Largo, there are 2 spa hotels.
What's there to see and do in Key Largo?
Enjoy Key Largo and visit Jimmy Johnson's Big Chill, Bluefin Rock Harbor Marina, and John Pennekamp Coral Reef State Park. If you have a bit of extra time while you're in the area, you might want to check out MarineLab Undersea Laboratory and Caribbean Club Bar.
What is a Key Largo spa hotel?
Spa hotels in Key Largo provide lodging and have an on-site spa offering services including facials and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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