Find hotels in Grand Isle, Port St. Joe from ￥9,196

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 11 - Aug 12
Tomorrow
Aug 12 - Aug 13
This weekend
Aug 15 - Aug 17
Next weekend
Aug 22 - Aug 24

Filter by

Guest rating
Guest rating
Star rating

Discover 2,149 Grand Isle hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

MainStay Suites Port Saint Joe South
Suite, Multiple Beds, Accessible, Non Smoking | Desk, iron/ironing board, free WiFi, bed sheets

MainStay Suites Port Saint Joe South

2.5 star property
8.6 out of 10, Excellent, (660)
"Great hotel , great bed , quiet !!!!"
The price is ￥17,153
￥19,211 total
includes taxes & fees
Aug 25 - Aug 26
MainStay Suites Port Saint Joe South
The Port Inn and Cottages, Ascend Hotel Collection
Lobby

The Port Inn and Cottages, Ascend Hotel Collection

3.5 star property
9.0 out of 10, Wonderful, (375)
"The staff here were exemplary. So very friendly and helpful. "
The price is ￥16,200
￥18,144 total
includes taxes & fees
Aug 18 - Aug 19
The Port Inn and Cottages, Ascend Hotel Collection
Cape Cottages by Panhandle Getaways
Aerial view

Cape Cottages by Panhandle Getaways

3.5 star property
The price is ￥19,777
￥82,215 total
includes taxes & fees
Aug 19 - Aug 20
Cape Cottages by Panhandle Getaways
Candlewood Suites Panama City Tyndall AFB by IHG
Exterior

Candlewood Suites Panama City Tyndall AFB by IHG

2.5 star property
9.0 out of 10, Wonderful, (12)
"The staff was nice, the room was clean the pool was clean and loved that they had a laundry room."
The price is ￥16,200
￥17,509 total
includes taxes & fees
Aug 22 - Aug 23
Candlewood Suites Panama City Tyndall AFB by IHG
Comfort Suites
Lobby

Comfort Suites

2.5 star property
8.6 out of 10, Excellent, (686)
"It was not too far from the beach and other activities "
The price is ￥13,164
￥14,227 total
includes taxes & fees
Aug 17 - Aug 18
Comfort Suites
Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG
Free buffet breakfast

Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

2.5 star property
8.4 out of 10, Very Good, (426)
"Great breakfast rooms large clean, "
The price is ￥18,172
￥19,638 total
includes taxes & fees
Sep 1 - Sep 2
Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG
Days Inn by Wyndham Panama City/Callaway
1 bedroom, laptop workspace, iron/ironing board, free cribs/infant beds

Days Inn by Wyndham Panama City/Callaway

2.0 star property
6.8 out of 10, (449)
"This property was right across from the beach. And the pool over looking the water was very nice"
The price is ￥9,196
￥9,938 total
includes taxes & fees
Aug 18 - Aug 19
Days Inn by Wyndham Panama City/Callaway
Extended Stay America Select Suites - Panama City - Callaway
Standard Studio, Non Smoking, Refrigerator & Microwave | Desk, laptop workspace, iron/ironing board, free WiFi

Extended Stay America Select Suites - Panama City - Callaway

2.5 star property
6.2 out of 10, (482)
"great stay"
The price is ￥10,636
￥11,493 total
includes taxes & fees
Aug 13 - Aug 14
Extended Stay America Select Suites - Panama City - Callaway
Cape San Blas Inn
Exterior

Cape San Blas Inn

3.0 star property
9.8 out of 10, Exceptional, (79)
"Great host excellent location we will be back"
Cape San Blas Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Grand Isle

Find the best Grand Isle areas and neighborhoods for the activities you enjoy most.
Downtown Port St. Joe map

Downtown Port St. Joe

While visiting Downtown Port St. Joe, you might make a stop by sights like Port Saint Joe City Hall and Port St. Joe Marina.

Cape Breezes map

Cape Breezes

While Cape Breezes isn't home to many top sights, T.H. Stone Memorial St. Joseph Peninsula State Park and St. Joseph Peninsula State Park are some notable places to visit nearby.

Gulf Aire map

Gulf Aire

While Gulf Aire isn't home to many top sights, Saint Joe Beach and Mexico Beach are some notable places to visit nearby.

Waterside Village map

Waterside Village

Though Waterside Village might not have many top sights, you can venture to the surrounding area to see attractions like Mexico Beach Marina and Mexico Beach.

Palms map

Palms

While there might not be top attractions in Palms, you can explore the larger area and discover places like Mexico Beach and Mexico Beach Marina.

Top Grand Isle Hotel Reviews

Comfort Suites

Comfort Suites

10/10 Excellent
"It was not too far from the beach and other activities "
Shaunte 3-night trip
Posted 4 days ago
Comfort Suites

Frequently asked questions

What is Grand Isle like?

Travelers to Mexico Beach's Grand Isle neighborhood will be sure to enjoy a stay in this neighborhood.

Where is the best place to stay in Grand Isle?

For your stay in Grand Isle, Mexico Beach Retreat w/ Grill & Private Pool! is one of the top choices based on our traveler data.

How many hotels will I find in Grand Isle?

Expedia has 7 Grand Isle hotels and other accommodations, and one might make a good home base for venturing out into the greater Mexico Beach area.

If I need to cancel my hotel reservation in Grand Isle, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to view the best options available in Grand Isle.

Where can I learn more about changing or cancelling my trip to Grand Isle?

For more details about rescheduling or cancelling your trip to Grand Isle, go to https://www.expedia.com/service/.

What is there to do around this Mexico Beach neighborhood?

Places you might want to visit in the area around Grand Isle include Mexico Beach and Mexico Beach Marina. When you're sightseeing around the area, Saint Joe Beach and Round Timber Island are a couple of other sights to visit.