Find Boutique Hotels in Downtown Cincinnati, OH

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Check availability on Downtown Cincinnati Boutique Hotels

Our top choices for Downtown Cincinnati boutique hotels

Egyptian cotton sheets, premium bedding, in-room safe, laptop workspace
21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati
4.5 star property
Downtown Cincinnati
8.8 out of 10, Excellent, (1002)
"Very clean rooms, great bar, friendly staff."
United States
Theodore
The price is ￥23,699
￥29,053 total
includes taxes & fees
Jan 1 - Jan 2, 2026
21c Museum Hotel Cincinnati
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Downtown Cincinnati Hotel Reviews

The Cincinnatian Hotel Curio Collection by Hilton

The Cincinnatian Hotel Curio Collection by Hilton

10/10 Excellent
"I love this hotel and plan to stay here every time I am in Cincinnati. The staff are fabulous, the room is spacious and very quiet. Excellent accommodation "
Casonti 3-night trip
Posted 3 days ago
The Cincinnatian Hotel Curio Collection by Hilton

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Frequently asked questions

What's the best boutique-style hotel in Downtown Cincinnati?
21c Museum Hotel Cincinnati is a favorite hotel with Expedia travelers looking for a stylish stay, and features a full-service spa and massages.
What's there to see and do in Downtown Cincinnati?
Visitors speak positively about this destination's art galleries, acclaimed theaters, and great live music. Activities and attractions to experience around Downtown Cincinnati include Fountain Square, Paycor Stadium, and National Underground Railroad Freedom Center. You might also like to explore more of the area and take in additional sights like The Andrew J Brady Music Center, Aronoff Center for the Arts, and Cincinnati Reds Hall of Fame and Museum while you're here.
What's the best way to get to my boutique hotel in Downtown Cincinnati?
You have a few options for getting to Downtown Cincinnati. The nearest major airport is Cincinnati, OH (LUK-Cincinnati Municipal - Lunken Field), which is located 4.7 mi (7.5 km) away, but Cincinnati-Northern Kentucky Int'l Airport (CVG) may also be an option. Nearby metro stations include Fountain Square Tram Stop, Cincinnati Cyclones Tram Stop, and 247 Telemarketing Tram Stop.