A calm lake with mountains in the background and a sunset.

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Check availability on Clemson Resorts & Hotels with Spas

This weekend
Nov 6 - Nov 8
Next weekend
Nov 13 - Nov 15

Our top choices for Clemson hotels with a spa

A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.

1. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
Clemson
9.8 out of 10, Exceptional, (907 reviews)
"Always a wonderful stay!"
United States
Laurrie
The price is ￥33,095
￥36,735 total
includes taxes & fees
Nov 8 - Nov 9
The Shepherd Hotel Downtown Clemson
A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.

2. The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
Clemson
9.6 out of 10, Exceptional, (659 reviews)
"Great place."
United States
John
The price is ￥22,660
￥25,155 total
includes taxes & fees
Nov 25 - Nov 26
The Abernathy of Clemson
A cozy living room with a fireplace, a dining area with a table and chairs, and a large wooden door.

3. Clemson Memorabilia House

Clemson Memorabilia House
3.0 star property
Clemson
9.6 out of 10, Exceptional, (10 reviews)
"We enjoyed our stay, it was the perfect size for our family of four. "
United States
Ashley
The price is ￥14,093
￥37,616 total
includes taxes & fees
Nov 10 - Nov 11
Clemson Memorabilia House
A bar area with a granite countertop, bar stools, and a menu board.

4. Courtyard Marriott Clemson

Courtyard Marriott Clemson
3.0 star property
Clemson
9.0 out of 10, Wonderful, (595 reviews)
"Exactly what I needed and was a clean hotel"
United States
Riley
The price is ￥16,342
￥18,139 total
includes taxes & fees
Nov 22 - Nov 23
Courtyard Marriott Clemson
A modern kitchen area with a bar counter and seating.

5. Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area
2.5 star property
Clemson
8.8 out of 10, Excellent, (654 reviews)
"Smelly, old, and dark rooms but that's what you get for these crazy prices in Clemson on gameday. Anything better is WAY overpriced. Breakfast was great and so was the staff."
United States
JESSE
The price is ￥17,363
￥19,275 total
includes taxes & fees
Nov 16 - Nov 17
Hampton Inn Clemson-University Area
A Holiday Inn Express hotel with a stone facade, large windows, and a parking lot.

6. Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
2.5 star property
Clemson
8.8 out of 10, Excellent, (999 reviews)
"Wonderful place to stay."
United States
John
The price is ￥20,427
￥22,674 total
includes taxes & fees
Nov 8 - Nov 9
Holiday Inn Express & Suites Clemson by IHG
A modern kitchen with a microwave, coffee maker, and bar stools.

7. Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
Clemson
8.4 out of 10, Very good, (1,003 reviews)
"Clean, walkable to downtown!"
United States
melissa
The price is ￥16,017
￥17,778 total
includes taxes & fees
Nov 29 - Nov 30
Comfort Inn & Suites Clemson - University Area
A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.

8. Inn @ Clemson

Inn @ Clemson
2.5 star property
Clemson
8.0 out of 10, Very good, (1,004 reviews)
"Clean room, comfortable beds, good breakfast, great price!"
United States
Kristi
The price is ￥11,923
￥13,233 total
includes taxes & fees
Nov 8 - Nov 9
Inn @ Clemson
A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.

9. Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.0 out of 10, Very good, (1,001 reviews)
"I have stayed here several times and it has always been a great experience. The rooms are clean and the staff is friendly."
United States
Alyssa
The price is ￥16,017
￥17,778 total
includes taxes & fees
Dec 3 - Dec 4
Best Western Plus Clemson Hotel & Conference Center
A hotel lobby with a reception desk, seating area, and a view of the street outside.

10. Econo Lodge Clemson - University Area

Econo Lodge Clemson - University Area
2.0 star property
Clemson
7.2 out of 10, Good, (160 reviews)
"Good location . Good price. Nice and quiet. Unusually good tv show choices. (Much better than last 4 or 5 hotels that I stayed at!)"
United States
Ruth
The price is ￥11,979
￥13,538 total
includes taxes & fees
Nov 26 - Nov 27
Econo Lodge Clemson - University Area
A dining area with a table and chairs, large windows with a view of the outside, and a green sofa.

11. Days Inn by Wyndham Clemson

Days Inn by Wyndham Clemson
3.5 star property
Clemson
6.8 out of 10, (237 reviews)
"While the hotel is close to Clemson, the property/ rooms were GROSS!! The bathroom had been wiped down, but whoever cleaned it missed the soap and shampoo left up top on the rim. The AC smelt so strongly of mildew/ mold that we could NOT turn it on. The whole room smelled like wet towels"
United States
Stephanie
The price is ￥13,388
￥14,859 total
includes taxes & fees
Nov 8 - Nov 9
Days Inn by Wyndham Clemson
A covered outdoor seating area with a table and chairs, a door leading inside, and a view of trees and a garden.

12. Clemson Game Day Cottage w/ Fire Pit

Clemson Game Day Cottage w/ Fire Pit
3.0 star property
Clemson
10.0 out of 10, Exceptional, (1 review)
The price is ￥25,811
￥46,927 total
includes taxes & fees
Nov 9 - Nov 10
Clemson Game Day Cottage w/ Fire Pit
A spacious hallway with a patterned carpet, a sofa with cushions, a coffee table, and framed artwork on the walls.

13. The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
Clemson
9.8 out of 10, Exceptional, (938 reviews)
"Lovely place to stay."
United States
Jennifer
The price is ￥22,167
￥24,606 total
includes taxes & fees
Nov 22 - Nov 23
The Inn at Patrick Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Clemson

Pool
Breakfast included

Top Clemson Hotel Reviews

Frequently asked questions

Looking for a spa hotel in Clemson?
Treat yourself to some pampering and book a hotel with a spa. Check out the live music scene and local architecture in Clemson—your cultural tour starts here. Be sure to pay a visit to the monuments during your stay. Hotels with spas are the perfect way to break out of your routine and add a layer of luxury to your vacation.
What is the best spa hotel in Clemson?
Days Inn by Wyndham Clemson
How many spa hotels will I find in Clemson?
Among Expedia's 83 accommodation options in Clemson, there is 1 spa hotel.
What's there to see and do in Clemson?
Enjoy all that Clemson has to offer when you visit Fort Hill, Memorial Stadium, and Littlejohn Coliseum. If you have extra time while you're in the area, you might want to stop by Brooks Center for the Performing Arts and South Carolina Botanical Gardens.
What is a Clemson spa hotel?
Spa hotels in Clemson provide lodging and have an on-site spa offering services like couples massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.