Photo by Molly Bond

Find Luxury Hotels in Clarksdale, MS

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Pick from 1 Clarksdale Luxury Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Lobby sitting area
Quality Inn
2.5 star property
7.2 out of 10, Good, (578)
"Rooms have new carpet and furniture. But, the frig didnot work and the air conditioner made a lound npise all night."
The price is ￥13,771
per night
Jun 2 - Jun 3
Quality Inn
Don't see what you're looking for?
See all available properties in Clarksdale
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to Clarksdale?
Use Expedia to arrange your flight to Tunica, MS (UTM-Tunica Municipal) airport or Greenville, MS (GLH-Mid Delta Regional) airport, and then choose from a variety of places to stay that will deliver the luxury you seek. Amenities are important when you plan a trip, so we make it easy to find what you’d like to make your stay special. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Clarksdale has to offer. During your visit, you might want to enjoy the restaurants which Clarksdale is known for.
What's the best time to vacation in Clarksdale?
Planning for the weather is an important factor for making your trip to Clarksdale a success, especially when you’re splurging. The hottest months are usually July and August with an average temp of 79°F, while the coldest months are January and February with an average of 47°F. Average annual precipitation for Clarksdale is 55 inches.
What's there to see and do in Clarksdale?
Enjoy all that Clarksdale has to offer when you visit The Holy Moly Theatre, Delta Blues Museum, and Red’s Lounge. If you have spare time during your trip, you might want to make a stop at Rock and Blues Museum and Mississippi River.