A large white dome building with a red brick base, surrounded by green trees and a clear blue sky.

Search Vacation Homes in Central Missouri

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Central Missouri vacation homes

1. The Big House, Historic 4-Bedroom Home With Custom Art And Dedicated Workspace

The Big House, Historic 4-Bedroom Home With Custom Art And Dedicated Workspace
Jefferson City
10.0 out of 10, Exceptional, (38 reviews)
"Very spacious, has everything a big family needs for a place to stay. Will definitely consider it next time again."
United States
ALVIN
The price is ¥29,667
¥47,253 total
includes taxes & fees
Aug 10 - Aug 11
The Big House, Historic 4-Bedroom Home With Custom Art And Dedicated Workspace

2. Historic 4-bedroom pet friendly rental close to downtown.

Historic 4-bedroom pet friendly rental close to downtown.
Jefferson City
10.0 out of 10, Exceptional, (10 reviews)
"We loved staying here! Would definitely book again. "
United States
Hannah E.
The price is ¥35,496
¥76,465 total
includes taxes & fees
Aug 11 - Aug 12
Historic 4-bedroom pet friendly rental close to downtown.

3. Experience Historic Elegance in the Heart of Missouri’s Capital City

Experience Historic Elegance in the Heart of Missouri’s Capital City
Jefferson City
8.8 out of 10, Excellent, (25 reviews)
"Great place!"
United States
Megan R.
The price is ¥30,763
¥45,944 total
includes taxes & fees
Aug 31 - Sep 1
Experience Historic Elegance in the Heart of Missouri’s Capital City

4. Full House Just Steps Away from Missouri River, Katy Trail, Shopping & More!

Full House Just Steps Away from Missouri River, Katy Trail, Shopping & More!
Boonville
9.8 out of 10, Exceptional, (108 reviews)
"The owner was very responsive with questions, let us know about a problem that came up and when it was fixed. House was very well stocked with everything that we could have wanted to make ourselves at home. Very roomy. I would highly recommend this place and we are hoping to return in the future."
United States
Michelle
The price is ¥18,142
¥34,887 total
includes taxes & fees
Aug 16 - Aug 17
Full House Just Steps Away from Missouri River, Katy Trail, Shopping & More!

5. Downtown Retreat with large privacy fenced yard. Pet Friendly!

Downtown Retreat with large privacy fenced yard. Pet Friendly!
Warrensburg
10.0 out of 10, Exceptional, (64 reviews)
"Very nice place to stay! Only stayed for a few hours because we were just passing through, but the beds were very comfortable!"
United States
Zachary B.
The price is ¥19,720
¥29,896 total
includes taxes & fees
Aug 9 - Aug 10
Downtown Retreat with large privacy fenced yard. Pet Friendly!

6. Short term avail! 5 min from MIZZOU,Univ Hospital! Family sized,clean,fenced

Short term avail! 5 min from MIZZOU,Univ Hospital! Family sized,clean,fenced
Columbia
9.8 out of 10, Exceptional, (47 reviews)
"Very comfortable and friendly host!"
United States
Troy V.
The price is ¥16,896
¥30,074 total
includes taxes & fees
Aug 19 - Aug 20
Short term avail! 5 min from MIZZOU,Univ Hospital! Family sized,clean,fenced

7. The Orchard House: Close to the Katy Trail, Truman Lake and Historic Downtown

The Orchard House: Close to the Katy Trail, Truman Lake and Historic Downtown
Clinton
9.6 out of 10, Exceptional, (34 reviews)
"This house was so cute. It was on a dead end street and was very quiet. It was easy to access and was a good central spot while I was in Clinton visiting family. Would definitely stay here again."
United States
Cailyn
The price is ¥17,038
¥27,671 total
includes taxes & fees
Aug 10 - Aug 11
The Orchard House: Close to the Katy Trail, Truman Lake and Historic Downtown

8. Treetop VIllage Four Seasons #10-Lakefront/2BD/3BA/Pools/Grill/Dock-4PP

Treetop VIllage Four Seasons #10-Lakefront/2BD/3BA/Pools/Grill/Dock-4PP
Village of Four Seasons
8.8 out of 10, Excellent, (13 reviews)
"Communication was a little difficulty at times but overall we loved our time here!"
United States
Kelley H.
The price is ¥15,618
¥48,803 total
includes taxes & fees
Sep 8 - Sep 9
Treetop VIllage Four Seasons #10-Lakefront/2BD/3BA/Pools/Grill/Dock-4PP

9. 3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena

3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena
Columbia
9.6 out of 10, Exceptional, (14 reviews)
"Great place to stay! "
United States
Stacy B.
The price is ¥23,348
¥56,448 total
includes taxes & fees
Sep 1 - Sep 2
3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena

10. Relax Enjoy Country Living-Hot Tub & Seasonal Pool

Relax Enjoy Country Living-Hot Tub & Seasonal Pool
New Franklin
10.0 out of 10, Exceptional, (11 reviews)
"We really enjoyed our stay. It is such a tranquil property and Jill was an amazing host. "
United States
Mike P.
The price is ¥30,527
¥63,955 total
includes taxes & fees
Aug 10 - Aug 11
Relax Enjoy Country Living-Hot Tub & Seasonal Pool

11. Cozy House On The HILL Military Family Favorite

Cozy House On The HILL Military Family Favorite
Waynesville
10.0 out of 10, Exceptional, (60 reviews)
"Lovely and relaxing place to stay. Easy walking distance o downtown and park"
United States
Shelley
The price is ¥18,742
¥33,221 total
includes taxes & fees
Aug 10 - Aug 11
Cozy House On The HILL Military Family Favorite

12. Newly Built Home w/ Fresh Design!

Newly Built Home w/ Fresh Design!
Columbia
9.8 out of 10, Exceptional, (26 reviews)
"Better than a hotel for gathering, eating, hanging out with college kids for mom’s weekend. "
United States
Jenny R.
The price is ¥29,959
¥54,612 total
includes taxes & fees
Aug 12 - Aug 13
Newly Built Home w/ Fresh Design!

13. Relax At Rt.66 Military Family Favorite

Relax At Rt.66 Military Family Favorite
Waynesville
9.8 out of 10, Exceptional, (42 reviews)
"Excellent property! We enjoyed our 5 day stay! Exceptionally well maintained and kept home. Easily accessible to downtown."
United States
David S.
The price is ¥15,965
¥29,807 total
includes taxes & fees
Aug 9 - Aug 10
Relax At Rt.66 Military Family Favorite

14. Simply Sweet 3 Bedroom Home - near MS&T & Fort Leonard Wood

Simply Sweet 3 Bedroom Home - near MS&T & Fort Leonard Wood
Rolla
9.6 out of 10, Exceptional, (43 reviews)
"Great stay!!"
United States
Liz H.
The price is ¥13,410
¥35,190 total
includes taxes & fees
Aug 9 - Aug 10
Simply Sweet 3 Bedroom Home - near MS&T & Fort Leonard Wood

15. Home Away From Home

Home Away From Home
Warrensburg
10.0 out of 10, Exceptional, (45 reviews)
"Place was excellent!!"
United States
Garrett
The price is ¥18,773
¥32,624 total
includes taxes & fees
Aug 25 - Aug 26
Home Away From Home

16. Cozy Home on the edge of Rolla!

Cozy Home on the edge of Rolla!
Rolla
9.6 out of 10, Exceptional, (19 reviews)
"Nice space, wonderful host. "
United States
Frank J.
The price is ¥11,990
¥27,091 total
includes taxes & fees
Aug 10 - Aug 11
Cozy Home on the edge of Rolla!

17. Haven House New Comfortable and Clean Retreat

Haven House New Comfortable and Clean Retreat
Sedalia
10.0 out of 10, Exceptional, (36 reviews)
"Awesome place to stay in Sedalia, beautiful cosy home. Top notch host. Would definitely recommend and stay again."
Canada
James
The price is ¥23,506
¥28,715 total
includes taxes & fees
Aug 10 - Aug 11
Haven House New Comfortable and Clean Retreat

18. The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James

The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James
Saint James
10.0 out of 10, Exceptional, (34 reviews)
"Beautifully appointed and great location for exploring the area!"
United States
Laura P.
The price is ¥21,589
¥26,115 total
includes taxes & fees
Aug 10 - Aug 11
The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James

19. Country Townhouse near Osage River: Go boating, UTV gravel roading, fishing!

Country Townhouse near Osage River: Go boating, UTV gravel roading, fishing!
Bonnots Mill
10.0 out of 10, Exceptional, (23 reviews)
"Excellent communication with the property manager and space was exactly as described. Would stay again."
United States
Julia M.
The price is ¥31,868
¥53,278 total
includes taxes & fees
Aug 17 - Aug 18
Country Townhouse near Osage River: Go boating, UTV gravel roading, fishing!

20. Relaxing Three Bedroom Getaway in Boonville

Relaxing Three Bedroom Getaway in Boonville
Boonville
9.6 out of 10, Exceptional, (30 reviews)
"Great place. Adorable decor, clean home. Convenient to Mizzou!"
United States
Biology N.
The price is ¥25,557
¥37,578 total
includes taxes & fees
Aug 9 - Aug 10
Relaxing Three Bedroom Getaway in Boonville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Central Missouri Hotel Reviews

Find out more about Central Missouri

Central Missouri Vacation Homes information

Number of reviews
695
Accommodation
837 Vacation Homes
Lowest Price
¥26,115
Highest Price
¥76,465

Explore a world of travel with Expedia