Find hotels near Buffalo Museum of Science, Buffalo from ￥17,767

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Dec 30 - Dec 31
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Dec 31 - Jan 1
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Jan 2 - Jan 4
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Our top choices for Buffalo Museum of Science hotels

Interior
InnBuffalo off Elmwood

InnBuffalo off Elmwood

InnBuffalo off Elmwood
2.5 star property
Elmwood Village, 3 km from Buffalo Museum of Science
10.0 out of 10, Exceptional, (190)
"Our favorite inn!! Beautifully and lovingly restored — wonderful staff, rooms, fresh breakfasts…a gem, to be sure."
United States
katherine
The price is ￥18,061
￥20,723 total
includes taxes & fees
Jan 8 - Jan 9, 2026
InnBuffalo off Elmwood
Staircase
The Edward Hotel

The Edward Hotel

The Edward Hotel
3.0 star property
Elmwood Village, 2.4 km from Buffalo Museum of Science
9.6 out of 10, Exceptional, (219)
"Great location in Elmwood Village area. Clean room with gas fireplace. Self check- in was easy with staff provided instructions. Many food options within walking distance. "
United States
Jon
The Edward Hotel
Lobby
Wyndham Garden Buffalo Downtown

Wyndham Garden Buffalo Downtown

Wyndham Garden Buffalo Downtown
3.0 star property
Downtown Buffalo, 2 km from Buffalo Museum of Science
9.0 out of 10, Wonderful, (1723)
"Great hotel!"
United States
Donovan
The price is ￥19,289
￥22,520 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Wyndham Garden Buffalo Downtown
Reception
Buffalo Harmony House

Buffalo Harmony House

Buffalo Harmony House
4.5 star property
Allentown, 3.2 km from Buffalo Museum of Science
10.0 out of 10, Exceptional, (47)
"Amazing breakfasts!"
United States
David
Buffalo Harmony House
Exterior
The Mansion On Delaware Ave

The Mansion On Delaware Ave

The Mansion On Delaware Ave
4.0 star property
Allentown, 3 km from Buffalo Museum of Science
9.4 out of 10, Exceptional, (1003)
"Fantastic place!"
Canada
Geneviève
The Mansion On Delaware Ave
Exterior
Buffalo Guesthouse

Buffalo Guesthouse

Buffalo Guesthouse
3.0 star property
Allentown, 2.4 km from Buffalo Museum of Science
9.0 out of 10, Wonderful, (120)
"Fantastic stay at the Buffalo Guesthouse. It has a real home feeling. Lovely staff( real friendly atmosphere where you actually engage with other people staying there. Clean, well located and secure. "
Australia
Benjamin
The price is ￥16,522
￥18,958 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Buffalo Guesthouse
Restaurant
Residence Inn by Marriott Buffalo Downtown

Residence Inn by Marriott Buffalo Downtown

Residence Inn by Marriott Buffalo Downtown
3.0 star property
Allentown, 2.6 km from Buffalo Museum of Science
9.0 out of 10, Wonderful, (337)
"Very comfortable, pleasant staff, great breakfast Clean, convenient, easy safe parking . Exceptional "
United States
Raymond
The price is ￥32,145
￥37,530 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Residence Inn by Marriott Buffalo Downtown
Suite, 1 King Bed, Non Smoking, Jetted Tub | Desk, laptop workspace, blackout drapes, iron/ironing board
Best Western on the Avenue

Best Western on the Avenue

Best Western on the Avenue
2.5 star property
Allentown, 2.8 km from Buffalo Museum of Science
8.6 out of 10, Excellent, (1000)
"The rooms were great. The staff was friendly and professional. Breakfast was awesome. Allentown location was ideal. I would stay here for my next visit."
United States
DAVID
The price is ￥20,917
￥24,421 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Best Western on the Avenue
1 bedroom, in-room safe, desk, laptop workspace
Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG
2.5 star property
Buffalo Theater District, 3.1 km from Buffalo Museum of Science
8.6 out of 10, Excellent, (1002)
"The room was very spacious and clean."
United States
Connie
The price is ￥17,536
￥20,473 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG
In-room safe, blackout drapes, free cribs/infant beds, free WiFi
Aloft Buffalo Downtown

Aloft Buffalo Downtown

Aloft Buffalo Downtown
3.0 star property
Buffalo Theater District, 3 km from Buffalo Museum of Science
8.2 out of 10, Very Good, (347)
"Clean room. Easy access to parking garage. "
United States
Clay
The price is ￥33,066
￥38,604 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Aloft Buffalo Downtown
Luxury House, 4 Bedrooms, Patio, City View | Private kitchen | Full-size fridge, microwave, oven, stovetop
Summer Street Guest House

Summer Street Guest House

Summer Street Guest House
3.0 star property
Bryant, 3 km from Buffalo Museum of Science
10.0 out of 10, Exceptional, (2)
"Beautiful old mansion lovingly restored with so much charm! This was a fantastic location for our needs. We were able to walk past estates and cute cottages with beautiful gardens to shops and restaurants for breakfast and lunch. Close to the Buffalo History Museum and other local attractions and about 20 minutes from Niagara Falls. Our host was able to let us have an early check in time and he gave us a tour of the house with some interesting background info. He lives quietly on the third...
United States
Anonymous traveler
The price is ￥56,009
￥82,169 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Summer Street Guest House
2 bars/lounges
Curtiss Hotel, an Ascend Collection Hotel

Curtiss Hotel, an Ascend Collection Hotel

Curtiss Hotel, an Ascend Collection Hotel
5.0 star property
Buffalo Theater District, 3.4 km from Buffalo Museum of Science
9.2 out of 10, Wonderful, (1006)
"Beautiful hotel, beautiful room, outside hot tub and excellent restaurant "
United States
valerie
The price is ￥32,450
￥37,886 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Curtiss Hotel, an Ascend Collection Hotel
Exterior
The Westin Buffalo

The Westin Buffalo

The Westin Buffalo
4.0 star property
Buffalo Theater District, 3.3 km from Buffalo Museum of Science
9.2 out of 10, Wonderful, (402)
"Our go-to in Buffalo ,,"
Canada
Sarah
The price is ￥40,396
￥47,162 total
includes taxes & fees
Jan 25 - Jan 26, 2026
The Westin Buffalo
Exterior
Hampton Inn & Suites Buffalo Downtown

Hampton Inn & Suites Buffalo Downtown

Hampton Inn & Suites Buffalo Downtown
2.5 star property
Buffalo Theater District, 3.4 km from Buffalo Museum of Science
8.8 out of 10, Excellent, (1003)
"Great location "
United States
Oscar
The price is ￥20,719
￥24,190 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Hampton Inn & Suites Buffalo Downtown
Hallway
The Richardson Hotel

The Richardson Hotel

The Richardson Hotel
3.5 star property
Elmwood Bidwell, 4.1 km from Buffalo Museum of Science
9.0 out of 10, Wonderful, (1006)
"Rhe property is amazing and the staff are too. Jessica made our stay special"
United States
Cindy
The price is ￥19,646
￥22,938 total
includes taxes & fees
Jan 7 - Jan 8, 2026
The Richardson Hotel
Exterior detail
Hilton Garden Inn Buffalo Downtown

Hilton Garden Inn Buffalo Downtown

Hilton Garden Inn Buffalo Downtown
3.0 star property
Buffalo Theater District, 3.5 km from Buffalo Museum of Science
8.6 out of 10, Excellent, (1004)
"Everything was amazing even the front desk very helpful and very knowledgeable about the area. Thanks for the hospitality "
United States
Omar
The price is ￥15,217
￥17,767 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Hilton Garden Inn Buffalo Downtown
Lobby
Hotel at the Lafayette Trademark Collection by Wyndham

Hotel at the Lafayette Trademark Collection by Wyndham

Hotel at the Lafayette Trademark Collection by Wyndham
3.5 star property
Buffalo Theater District, 3.6 km from Buffalo Museum of Science
8.6 out of 10, Excellent, (1004)
"I love the history in the hotel "
United States
Dylan
The price is ￥16,837
￥19,657 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Hotel at the Lafayette Trademark Collection by Wyndham
Indoor pool
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center
3.5 star property
Buffalo Theater District, 3.4 km from Buffalo Museum of Science
8.2 out of 10, Very Good, (1702)
"The staff was so friendly would highly recommended this place."
United States
kyle
The price is ￥18,971
￥22,149 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Hyatt Regency Buffalo / Hotel and Conference Center
Exterior
Courtyard Buffalo Downtown / Canalside

Courtyard Buffalo Downtown / Canalside

Courtyard Buffalo Downtown / Canalside
3.0 star property
Downtown Buffalo, 4.3 km from Buffalo Museum of Science
9.0 out of 10, Wonderful, (960)
"Very clean room, nice pool with lots of towels, good breakfast selection. "
United States
Jessica
The price is ￥27,045
￥31,575 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Courtyard Buffalo Downtown / Canalside
Exterior
Embassy Suites Buffalo

Embassy Suites Buffalo

Embassy Suites Buffalo
3.5 star property
Buffalo Theater District, 3.4 km from Buffalo Museum of Science
8.2 out of 10, Very Good, (1001)
"Great room "
United States
David
The price is ￥25,549
￥29,828 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Embassy Suites Buffalo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Buffalo Museum of Science Hotel Reviews

Residence Inn by Marriott Buffalo Downtown

Residence Inn by Marriott Buffalo Downtown

10/10 Excellent
"Very comfortable, pleasant staff, great breakfast Clean, convenient, easy safe parking . Exceptional "
Raymond 2-night trip
Posted 3 days ago
Residence Inn by Marriott Buffalo Downtown

Hotels near other Buffalo Museum of Science attractions

Buffalo Central Terminal

You can find out about the history of Buffalo when you stop by Buffalo Central Terminal. Experience the great live music and entertainment choices in this vibrant area.
See properties

War Memorial Stadium

Explore the great outdoors at War Memorial Stadium, a lovely green space in Buffalo. Experience the area's entertainment choices and acclaimed theater scene.
See properties

Frequently asked questions

What's the area like around Buffalo Museum of Science?
Buffalo Museum of Science is located in a historic area of Buffalo known for its great live music scene. If you're looking for a convenient place to stay, check out the 10 hotels and other accommodations you'll find within a mile.
What's the best hotel to stay near Buffalo Museum of Science?
Hyatt Regency Buffalo / Hotel and Conference Center is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an indoor pool. It's located 2.1 mi (3.4 km) from Buffalo Museum of Science. Other good choices within 5 miles include Wyndham Garden Buffalo Downtown and Buffalo Guesthouse.
How many hotels will I be able to find close to Buffalo Museum of Science?
Expedia has 10 hotels and other accommodations within a mile from Buffalo Museum of Science.
If I need to cancel the hotel reservation for my stay near Buffalo Museum of Science, will I receive a refund?
Yes, most hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the top deals on offer near Buffalo Museum of Science.
Where can I learn more about changing or cancelling my trip in the area near Buffalo Museum of Science?
For more information about picking new dates or cancelling your stay near Buffalo Museum of Science, go to https://www.expedia.com/service/.
What can I see and do near Buffalo Museum of Science?
Study the collections at Buffalo AKG Art Museum, Buffalo History Museum, or Buffalo and Erie County Naval and Military Park. Some landmarks that you won't want to miss include Buffalo Central Terminal, Statler Tower, and Peace Bridge. You can watch performances at Shea's Performing Arts Center, Kleinhans Music Hall, and Road Less Traveled Theater if you're interested in local theater.