A signpost with distance markers for Chicago and Los Angeles.

Find hotels in Adrian, TX from ￥12,151

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This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

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Our top choices for Adrian hotels

A Country Inn with a red and white color scheme, a reception desk, a coffee bar, and a large window with blinds.

1. Route 66 Desert Rose Country Inn

Route 66 Desert Rose Country Inn
2.5 star property
Vega
8.0 out of 10, Very good, (455 reviews)
"Great hotel and great breakfast and very clean room"
United States
Marquitta
The price is ￥10,848
￥12,151 total
includes taxes & fees
Nov 12 - Nov 13
Route 66 Desert Rose Country Inn
A swimming pool with white chairs around it, a tiled border, and a window with a view.

2. Days Inn by Wyndham Vega TX

Days Inn by Wyndham Vega TX
2.0 star property
Vega
6.8 out of 10, (436 reviews)
"Rooms very very nice and clean. The staff was friendly and helpful with our checking and checkout."
United States
Gerald
The price is ￥13,410
￥15,019 total
includes taxes & fees
Nov 3 - Nov 4
Days Inn by Wyndham Vega TX
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Adrian attractions

Midway Point of Route 66

Stand at the exact midpoint of Route 66, where Chicago and Los Angeles are precisely 1,139 miles away. The historic Midpoint Café serves "ugly crust pies" in the spot that inspired Flo's V8 Café in Pixar's "Cars."
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Learn more about Adrian

At the midpoint of Route 66, stop at the Midpoint Café for their famous 'ugly crust' pies and Route 66 memorabilia. Snap a photo with the town's midway marker, then chat with locals who'll share stories about this tiny highway community.

See all hotels in Adrian
A road with 'Midpoint' marking, a 'Welcome' sign, and a 'Route 66' symbol.

Top Adrian Hotel Reviews

Route 66 Desert Rose Country Inn

Route 66 Desert Rose Country Inn

8/10 Good
"This is a good place to stay for the night. Owner and wife very friendly and helpful. Needs some updating, but that will come. Homemade muffins for breakfast! Yum!"
Patricia 1-night trip
Posted 2 days ago
Route 66 Desert Rose Country Inn

More cheap stays in Adrian

Route 66 Desert Rose Country Inn

Route 66 Desert Rose Country Inn

1800 West Vega Boulevard Vega TX
The price is ￥10,848 per night from Nov 12 to Nov 13
￥10,848
￥12,151 total
Nov 12 - Nov 13
includes taxes & fees
8/10 Very Good! (455 reviews)

Frequently asked questions

What's the best place for a stay in Adrian?
Located 13 mi (20.9 km) from the heart of Adrian, Route 66 Desert Rose Country Inn is a top choice for your stay based on our traveler data. Days Inn by Wyndham Vega TX is another good option for your stay in the area. See all available top hotels, or vacation rentals in Adrian.
What are some of the best vacation rentals that Adrian has to offer?
Route 66 Retreat: This vacation home rental outside of Adrian has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. See all vacation rentals in Adrian.
If I need to cancel my hotel reservation in Adrian, will I receive a refund?
Yes! Most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Adrian.
Where can I learn more about changing or cancelling my trip to Adrian?
To find more details about picking new dates or cancelling your trip to Adrian, head over to our customer service page.
What's the best hotel for staying near Rick Husband Amarillo International Airport (AMA)?
Holiday Inn Amarillo East is one of the top choices for your stay and is a popular 3-star hotel featuring a restaurant and an indoor pool. It's located 3.1 mi (5 km) from Rick Husband Amarillo Intl. Airport. Other good choices near the airport include Fairfield Inn & Suites Amarillo Airport and La Quinta Inn & Suites by Wyndham Amarillo Airport.
What's it like to stay in Adrian?
Visitors can enjoy all that Adrian has to offer including the local tours, shopping, and museums. There are 3 hotels and other accommodations in the surrounding area. Find out more about Adrian.
What should I see while I'm in Adrian?
A favorite place to visit is Midway Point of Route 66. Additionally, you'll find Magnolia Gas Station in the area. Check out what more to see and do in Expedia's Adrian guide.
What's the seasonal weather like in Adrian?
The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and December with an average of 43°F. Average annual precipitation for Adrian is 16 inches.