Find 4 Star Hotels in Eastern Panama from ￥84,184

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Check availability on Eastern Panama 4 Star Hotels

Tonight
Mar 2 - Mar 3
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Mar 3 - Mar 4
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Mar 6 - Mar 8
Next weekend
Mar 13 - Mar 15

Our top choices for Eastern Panama 4-star hotels

Luxury Suite | 1 bedroom, Egyptian cotton sheets, premium bedding, pillowtop beds

Ordovician Beach Resort

Ordovician Beach Resort
4.5 star property
Isla Grande
10.0 out of 10, Exceptional, (9 reviews)
"The best service in Panama!!! We truly felt cared for in every detail — the team is attentive, warm, and genuinely professional. The food was outstanding: the chef is exceptional! Every dish reflected passion, quality, and pride. This hotel is located on a beautiful Caribbean island, surrounded by untouched nature, turquoise waters, and a truly magical atmosphere. What made it even more special was the silence and privacy — only the sound of the waves and the singing of birds!) A wonderful...
United States
Yevhen
The price is ￥76,389
￥84,184 total
includes taxes & fees
Mar 6 - Mar 7
Ordovician Beach Resort
Room, Mountain View, Mountainside | Free WiFi

Mandalas Ecolodge

Mandalas Ecolodge
4.0 star property
Caimitillo
Mandalas Ecolodge
Outdoor pool

El Otro Lado

El Otro Lado
4.0 star property
Portobelo
9.8 out of 10, Exceptional, (8 reviews)
"Amazing.. Amazing. You need extra words, We loved it. We loved it.Amazing.. Amazing. You need extra words, We loved it. We loved it. Amazing.. Amazing. You need extra words, We loved it. We loved it. "
United States
Jacob
El Otro Lado
Premier Apartment, Bay View | Premium bedding, down comforters, individually decorated

Portobello Historico

Portobello Historico
4.0 star property
Portobelo
Portobello Historico
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Learn more about Eastern Panama

Explore attractions like Cayos Holandeses and Isla Diablo as you discover things to see and do in Eastern Panama.

See all hotels in Eastern Panama
50 Shades of blue. Sailing through the San Blas Islands in Panama lets you experience a pure paradise and crystal clear water. You can buy fresh fish and other seefood drirectly from local fishermen. If you want you can also play Robinson Crusoe on islands with literally only one palm tree. #BVSBlue
Photo by Nico Barner
Open Photo by Nico Barner

Top Eastern Panama Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Eastern Panama?
With Expedia's handy filter tool, scoring an awesome deal on a 4-star hotel in Eastern Panama just got simpler. Start by keying in your chosen arrival date and length of your vacation. Then sort the results by price and pick the option that best matches your budget and style.

  • Search for the lowest price from ￥84,184

What's the difference between 5-star and 4-star hotels in Eastern Panama?
If you decide to book a stay at a 4-star hotel in Eastern Panama, you'll usually find lots of conveniences to keep you comfortable, such as a pool, restaurant and gym. You can experience top-quality service and upscale accommodations. Go for a 5-star hotel and you'll have access to a few more bells and whistles — think on-site spas, concierge assistance and nightly turndown services. You'll most likely get extra amenities and premium services at a 5-star retreat, but both are terrific options for luxury guests.
Does Eastern Panama have any 4-star all-inclusive resorts?
Use our "All inclusive" filter to find your next getaway in Eastern Panama where just about everything is taken care of, from your meals to your accommodations, activities and entertainment. We can also help you find standard 4-star stays in and around this leading destination.