Flights to Southern Madrid from Istanbul - ￥17,155

View ￥17,155 flight on Sun, Oct 26, 2025Opens in a new window

Popular airlines from Istanbul to Southern Madrid

  • ITA Airways

    ITA Airways

  • KLM

    KLM

  • Lufthansa

    Lufthansa

  • Turkish Airlines

    Turkish Airlines

  • Air Europa

    Air Europa

  • Air France

    Air France

  • LOT-Polish Airlines

    LOT-Polish Airlines

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Cheap Flights from Istanbul to Southern Madrid (IST-MAD)

Prices were available within the past 7 days and start at ￥17,155 for one-way flights and ￥39,120 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Air Serbia
Fri, Mar 13 - Sun, Mar 15
IST
Istanbul
MAD
Madrid
￥39,120 Roundtrip, found 5 days ago
￥39,120
Roundtrip
found 5 days ago
Select Air Serbia flight, departing Fri, Mar 13 from Istanbul to Madrid, returning Sun, Mar 15, priced at ￥39,120 found 5 days ago
Lufthansa
Sat, Mar 14 - Mon, Mar 16
IST
Istanbul
MAD
Madrid
￥40,990 Roundtrip, found 5 days ago
￥40,990
Roundtrip
found 5 days ago
Select Lufthansa flight, departing Sat, Mar 14 from Istanbul to Madrid, returning Mon, Mar 16, priced at ￥40,990 found 5 days ago
LOT-Polish Airlines
Fri, Mar 13 - Sun, Mar 15
IST
Istanbul
MAD
Madrid
￥44,136 Roundtrip, found 5 days ago
￥44,136
Roundtrip
found 5 days ago
Select LOT-Polish Airlines flight, departing Fri, Mar 13 from Istanbul to Madrid, returning Sun, Mar 15, priced at ￥44,136 found 5 days ago
Air Europa
Fri, Mar 13 - Sun, Mar 15
IST
Istanbul
MAD
Madrid
￥47,628 Roundtrip, found 5 days ago
￥47,628
Roundtrip
found 5 days ago
Select Air Europa flight, departing Fri, Mar 13 from Istanbul to Madrid, returning Sun, Mar 15, priced at ￥47,628 found 5 days ago
KLM
Fri, Mar 13 - Sun, Mar 15
IST
Istanbul
MAD
Madrid
￥49,400 Roundtrip, found 5 days ago
￥49,400
Roundtrip
found 5 days ago
Select KLM flight, departing Fri, Mar 13 from Istanbul to Madrid, returning Sun, Mar 15, priced at ￥49,400 found 5 days ago
Aegean
Sun, Oct 12 - Fri, Oct 17
IST
Istanbul
MAD
Madrid
￥51,530 Roundtrip, found 2 days ago
￥51,530
Roundtrip
found 2 days ago
Select Aegean flight, departing Sun, Oct 12 from Istanbul to Madrid, returning Fri, Oct 17, priced at ￥51,530 found 2 days ago

Find the cheapest month to fly from Istanbul (IST) to Madrid (MAD)

February is typically the cheapest month to fly

From ￥21,483 - ￥40,031 per traveler.

Graph displaying average flight prices per month

*Available to Expedia members.