Missouri Luxury Vacations

Book a Luxury Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ¥45,448 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Top Luxury Missouri Hotels

 The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis

4.5 out of 5
212 N Kingshighway St. Louis MO
  • 6 min drive from St. Louis Union Station
The price is ¥22,184 per night from Dec 14 to Dec 15
¥22,184
¥30,734 total
Dec 14 - Dec 15
includes taxes & fees
Treat yourself to some luxurious accommodations at The Royal Sonesta Chase Park Plaza St. Louis, where you can enjoy amenities like pillowtop beds, designer ...
8.8/10 Excellent! (1,000 reviews)
The survey says the breakfast was free, however, we were not informed of that and spent over $40.00 at breakfast.

Reviewed on Nov 28, 2025

The Royal Sonesta Chase Park Plaza St. Louis
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
  • 34 min drive from St. Louis Union Station
The price is ¥23,603 per night from Dec 7 to Dec 8
¥23,603
¥30,158 total
Dec 7 - Dec 8
includes taxes & fees
Stay in the lap of luxury at Ameristar Casino Resort and Spa, where you can enjoy amenities like plush bedding, HDTVs, and more. Notable amenities include a ...
8.4/10 Very Good! (1,000 reviews)
Room was nice. Enjoyed the pool view and spaciousness. Staff was friendly upon arrival and departure.

Reviewed on Dec 2, 2025

Ameristar Casino Resort and Spa
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

5 out of 5
100 Carondelet Plaza St. Louis MO
  • 13 min drive from St. Louis Union Station
The price is ¥77,410 per night from Dec 22 to Dec 23
¥77,410
¥90,366 total
Dec 22 - Dec 23
includes taxes & fees
Be treated to a luxury stay at The Ritz-Carlton, St. Louis, where you can enjoy amenities like plush bedding, designer toiletries, and more. The 3 bars, fitness ...
9.2/10 Wonderful! (553 reviews)
Absolutely beautiful hotel!!! Highly recommend!

Reviewed on Nov 28, 2025

The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.