Southeastern United States Adults Only Vacations
Book a Adults Only Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to ￥45,448 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top Adults Only Southeastern United States Hotels
Shoreline Island Resort - Exclusively Adult
14200 Gulf Boulevard Madeira Beach FL
Book a stay at this beach aparthotel in Madeira Beach. Enjoy free WiFi, free parking, and a beach locale. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,449 reviews)
View from our room was amazing! having the pool and the beach right there, we loved it! The bed was super soft! Front desk staff was so friendly and helpful. Highly recommend!!!!
Reviewed on Feb 1, 2026
The Southernmost Inn - Adults Only
525 United Street Key West FL
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.2/10 Very Good! (1,273 reviews)
Staff was great. Location was perfect.
Reviewed on Feb 15, 2026
Paradise Inn Key West - Adults Only
819 Simonton Street Key West FL
Book a stay at this business-friendly hotel in Key West. Enjoy free breakfast, parking (surcharge), and daily housekeeping. Our guests praise the breakfast and ...
9/10 Wonderful! (1,001 reviews)
Wonderful stay in separate two bed, two bath cottage. So quiet and peaceful. It was like being miles away from the hustle and bustle but centrally located to everything. We would definitely stay there again.
Reviewed on Feb 10, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
