Flights to Historic Route 66 from Minneapolis - St. Paul - ￥6,660

View ￥6,660 flight on Wed, Aug 20, 2025Opens in a new window

Popular airlines from Minneapolis to Historic Route 66

  • Delta

    Delta

  • American Airlines

    American Airlines

  • United

    United

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 40% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Minneapolis - St. Paul to Historic Route 66 (MSP-CHI)

Prices were available within the past 7 days and start at ￥6,660 for one-way flights and ￥13,430 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Sun, Aug 24 - Sun, Aug 31
MSP
Minneapolis
ORD
Chicago
￥13,430 Roundtrip, found 4 days ago
￥13,430
Roundtrip
found 4 days ago
Select Delta flight, departing Sun, Aug 24 from Minneapolis to Chicago, returning Sun, Aug 31, priced at ￥13,430 found 4 days ago
Delta
Sun, Aug 24 - Sun, Aug 31
MSP
Minneapolis
ORD
Chicago
￥17,840 Roundtrip, found 4 days ago
￥17,840
Roundtrip
found 4 days ago
Select Delta flight, departing Sun, Aug 24 from Minneapolis to Chicago, returning Sun, Aug 31, priced at ￥17,840 found 4 days ago
American Airlines
Fri, Aug 29 - Mon, Sep 1
MSP
Minneapolis
ORD
Chicago
￥18,140 Roundtrip, found 4 days ago
￥18,140
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, Aug 29 from Minneapolis to Chicago, returning Mon, Sep 1, priced at ￥18,140 found 4 days ago
United
Fri, Aug 29 - Mon, Sep 1
MSP
Minneapolis
ORD
Chicago
￥19,750 Roundtrip, found 4 days ago
￥19,750
Roundtrip
found 4 days ago
Select United flight, departing Fri, Aug 29 from Minneapolis to Chicago, returning Mon, Sep 1, priced at ￥19,750 found 4 days ago
American Airlines
Fri, Aug 29 - Mon, Sep 1
MSP
Minneapolis
ORD
Chicago
￥20,510 Roundtrip, found 4 days ago
￥20,510
Roundtrip
found 4 days ago
Select American Airlines flight, departing Fri, Aug 29 from Minneapolis to Chicago, returning Mon, Sep 1, priced at ￥20,510 found 4 days ago
Delta
Sun, Aug 24 - Sun, Aug 31
MSP
Minneapolis
ORD
Chicago
￥20,880 Roundtrip, found 4 days ago
￥20,880
Roundtrip
found 4 days ago
Select Delta flight, departing Sun, Aug 24 from Minneapolis to Chicago, returning Sun, Aug 31, priced at ￥20,880 found 4 days ago

Find the cheapest month to fly from Minneapolis (MSP) to Chicago (ORD)

September is typically the cheapest month to fly

From ￥11,282 - ￥16,267 per traveler.

Graph displaying average flight prices per month

*Available to Expedia members.