South Houston Vacation Rentals

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Jan 2 - Jan 4
In two months
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In four months
Apr 10 - Apr 12

Our top choices for South Houston vacation rentals

Exterior
stayAPT Suites Houston NASA Clear Lake

Aparthotel in Webster

stayAPT Suites Houston NASA Clear Lake
2.5 star property
9.2 out of 10, Wonderful, (379)
"The place was so nice ! "
United States
Ariel
stayAPT Suites Houston NASA Clear Lake
Exterior
Reside Houston Dwntwn, Wyndham

Aparthotel in Downtown Houston

Reside Houston Dwntwn, Wyndham
3.5 star property
8.6 out of 10, Excellent, (855)
"Clean rooms, very nice front desk staff. "
United States
Nicholas
The price is ￥18,772
￥21,963 total
includes taxes & fees
Dec 22 - Dec 23
Reside Houston Dwntwn, Wyndham
Lunch and dinner served, Chinese cuisine
ACP Hotel Houston Westchase, MOD Collection by Sonesta

Aparthotel in Sharpstown

ACP Hotel Houston Westchase, MOD Collection by Sonesta
5.0 star property
8.0 out of 10, Very Good, (1007)
"room clean and staffs very nice and the hotel close to restaurants and shopping . I will stay there when I visit Houston Texas ."
United States
johnny
The price is ￥12,147
￥14,213 total
includes taxes & fees
Jan 21 - Jan 22, 2026
ACP Hotel Houston Westchase, MOD Collection by Sonesta
Bar (on property)
Hotel Ylem

Aparthotel in Braeswood Place

Hotel Ylem
3.5 star property
8.4 out of 10, Very Good, (2479)
"Room was clean, good breakfast and staff was very kind "
United States
Erika
The price is ￥9,123
￥11,462 total
includes taxes & fees
Dec 28 - Dec 29
Hotel Ylem
Premium bedding, pillowtop beds, minibar, in-room safe
Hotel Zaza Houston Museum District

Aparthotel in South Central Houston

Hotel Zaza Houston Museum District
4.5 star property
9.0 out of 10, Wonderful, (1857)
"Very nice room, great staff, excellent food & drink."
United States
Mary
Hotel Zaza Houston Museum District
Check-in/check-out kiosk
Rusk House Serviced Apartments

Aparthotel in Downtown Houston

Rusk House Serviced Apartments
4.5 star property
9.2 out of 10, Wonderful, (317)
"Really comfortable stay, friendly staff, plenty of public transit options nearby too."
Australia
Thomas
The price is ￥21,296
￥24,916 total
includes taxes & fees
Dec 23 - Dec 24
Rusk House Serviced Apartments
Townhome, Multiple Beds, Balcony (Marina Maison) | Private kitchen
Marina Maison 2bdr Condo

Townhouse in Clear Lake Shores

Marina Maison 2bdr Condo
2.0 star property
The price is ￥24,758
￥45,472 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Marina Maison 2bdr Condo
House | Private kitchen
Cozy 3BR Retreat w Office

Vacation Home in Northeast Houston

Cozy 3BR Retreat w Office
2.0 star property
The price is ￥17,154
￥78,135 total
includes taxes & fees
Dec 22 - Dec 23
Cozy 3BR Retreat w Office
House (3 Bedrooms) | Interior
2 Mi to Dtwn: Modern Houston Home w/ Private Patio

Cottage in Northside

2 Mi to Dtwn: Modern Houston Home w/ Private Patio
3.0 star property
The price is ￥15,460
￥49,526 total
includes taxes & fees
Dec 22 - Dec 23
2 Mi to Dtwn: Modern Houston Home w/ Private Patio
Deluxe Apartment, Balcony | Living area
Wonderful Getaway 1BR with Balcony Views

Apartment in Northside

Wonderful Getaway 1BR with Balcony Views
2.0 star property
The price is ￥12,347
￥84,646 total
includes taxes & fees
Dec 29 - Dec 30
Wonderful Getaway 1BR with Balcony Views
Courtyard
Hotel Granduca Houston

Hotel Granduca Houston

Hotel Granduca Houston
4.0 star property
9.2 out of 10, Wonderful, (1001)
"Beautiful room, hotel, and friendly staff "
United States
Alex
The price is ￥54,140
￥63,777 total
includes taxes & fees
Jan 17 - Jan 18, 2026
Hotel Granduca Houston
Living area
Stylish 1BR Urban Retreat

Apartment in Montrose

Stylish 1BR Urban Retreat
4.0 star property
The price is ￥11,863
￥32,246 total
includes taxes & fees
Dec 28 - Dec 29
Stylish 1BR Urban Retreat
House, 3 Bedrooms | Private kitchen | Fridge, oven, coffee/tea maker, electric kettle
Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home

Vacation Home in South Central Houston

Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home
3.0 star property
The price is ￥33,826
￥104,154 total
includes taxes & fees
Dec 22 - Dec 23
Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home
House, 3 Bedrooms, Non Smoking | Private kitchenette
Luxury 3BR for Families Nurses and Group

Apartment in Northside

Luxury 3BR for Families Nurses and Group
2.0 star property
The price is ￥26,976
￥55,223 total
includes taxes & fees
Dec 27 - Dec 28
Luxury 3BR for Families Nurses and Group
House | Private kitchen
Tima Luxury Rental

Residence in Northside

Tima Luxury Rental
2.5 star property
The price is ￥38,452
￥68,652 total
includes taxes & fees
Dec 22 - Dec 23
Tima Luxury Rental
Interior
4 BR Luxury Home in Friendswood

Vacation Home in Friendswood

4 BR Luxury Home in Friendswood
3.0 star property
The price is ￥51,269
￥85,540 total
includes taxes & fees
Jan 12 - Jan 13, 2026
4 BR Luxury Home in Friendswood
House, 3 Bedrooms | Living area
Luxury 3BR for Families Nurses and Group

Apartment in Northside

Luxury 3BR for Families Nurses and Group
3.0 star property
The price is ￥29,973
￥82,394 total
includes taxes & fees
Dec 26 - Dec 27
Luxury 3BR for Families Nurses and Group
Exterior
Cute Quiet Garage Apt Home

Vacation Home in Northside

Cute Quiet Garage Apt Home
2.0 star property
The price is ￥10,629
￥65,282 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Cute Quiet Garage Apt Home
House (4 Bedrooms) | Front of property
Covered Patio & Spacious Yard: Houston Area Home!

Cottage in Atascocita

Covered Patio & Spacious Yard: Houston Area Home!
3.0 star property
The price is ￥33,759
￥87,328 total
includes taxes & fees
Dec 22 - Dec 23
Covered Patio & Spacious Yard: Houston Area Home!
House, 3 Bedrooms | Free WiFi
Luxe 3BR for Families Nurses and Group

Apartment in Northside

Luxe 3BR for Families Nurses and Group
3.0 star property
The price is ￥29,973
￥82,394 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Luxe 3BR for Families Nurses and Group
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South Houston Hotel Reviews

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

10/10 Excellent
"Everything is great! "
Amy 2-night trip
Posted 1 day ago
Hilton Houston Plaza/Medical Center

Find out more about South Houston

Search for holiday rentals in South Houston on Expedia! You can easily find your home rentals, villas, holiday apartments in South Houston using one of the methods below:

  • View our selection of featured holiday rentals in South Houston
  • Use the map to find apartments and other holiday homes in the South Houston neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in South Houston while they last

Look no further and take a look at our great range of rental properties in South Houston!

Frequently asked questions

Can I find a vacation rental in South Houston?

Yes, we offer vacation rentals where you'll be just 11 mi (17.7 km) from NASA Johnson Space Center, giving you a secluded option if you want a quieter place to stay. South Houston is known for its university setting and basketball games. Make sure you have time to check out the shopping and temples during your trip.

What are some of the best vacation home rentals in South Houston?

Happy, Luxury and Fun Space. Mins to NRG, MedCntr and downtown Houston : Visitors like this South Houston vacation home rental. It offers a fireplace, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You can relax into your vacation with a selection of games and a hot tub.

What’s there to see and do in South Houston?

Explore the area and cultural attractions such as Toyota Center, or visit a family-friendly sight such as NASA Johnson Space Center. While in the area, you can also visit popular places like Daikin Park and NRG Stadium.

What’s a vacation rental in South Houston like?

A vacation rental is a private property you can stay in for short or long periods in South Houston. Vacation rentals offer amenities like laundry facilities and kitchens so you'll feel just like you're at home. If you're concerned about a sanitized environment, a vacation rental can offer a sense of security away from shared hotel elevators and busy lobbies while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental a great choice for family trips or small group gatherings.