São Francisco Vacations
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- Better togetherSave up to ￥109,000 when you book a flight and hotel together*
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Where to stay in São Francisco
Find the best São Francisco areas and neighborhoods for the activities you enjoy most. Learn more about São Francisco
Manaus Centro
2 out of top 10 points of interest in this area
Manaus Centro is noteworthy for its theaters, and you can make a stop at top attractions like Teatro Amazonas and Palacio Rio Negro.
Adrianopolis
1 out of top 10 points of interest in this area
Visitors to Adrianopolis enjoy its shopping, and if you want to do some exploring, Manauara Shopping is worth a stop.
Ponta Negra
1 out of top 10 points of interest in this area
Visitors to Ponta Negra enjoy its river views, and if you want to do some exploring, Ponta Negra Beach is worth a stop.
Industrial District
1 out of top 10 points of interest in this area
Industrial District is noteworthy for its restaurants, and you can make a stop at top attractions like Studio 5 Festival Mall Manaus and Convention Center and Povos da Amazonia Cultural Center.
Cidade Nova Manaus
While Cidade Nova Manaus might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Amazon Arena and Archipelago of Anavilhanas.
São Francisco Hotel Deals
Da Vinci Hotel & Conventions by Easy Hotéis
Rua Belo Horizonte, 240A - Adrianopolis Manaus AM
Fully refundableReserve now, pay when you stay
￥7,624
￥7,777 total
Nov 8 - Nov 9
includes taxes & fees
Hotel Intercity Manaus
Rua Professor Marciano Armond, 544 Manaus AM
Fully refundableReserve now, pay when you stay
￥13,112
￥13,374 total
Nov 7 - Nov 8
includes taxes & fees
Hotel Express Vieiralves
Rua Rio Branco, s/n Manaus AM
Fully refundableReserve now, pay when you stay
￥6,706
￥6,840 total
Oct 14 - Oct 15
includes taxes & fees
8.4/10 Very Good! (1,033 reviews)
"Nice breakfast and restaurant"
Reviewed on Sep 24, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a São Francisco vacation package cost?
Less than you might think — from a tempting , in fact! By bundling hotels, flights and car rentals into your own custom-made vacation package, your trip to São Francisco is just a few clicks away.
How do I get a cheap travel package to São Francisco?
It's easy. Just bundle everything together. Hotels, flights and rental cars — combine whatever you need into a São Francisco vacation package to save loads of cash. Score even bigger bargains when you add extras such as tours or experiences to your booking. But that's not the only impressive part. You have the freedom to tailor your vacation your way. We offer over 550 airlines and 1,000,000 hotels in all corners of the globe, so that everyone has a chance to travel and fulfill those vacation dreams.
Where should I stay in São Francisco?
A visit to São Francisco has to include Teatro Amazonas and Amazon Arena. Look for somewhere to stay as close as possible so you can easily access these impressive tourist attractions.
How far in advance should I book my São Francisco vacation?
It's hard to pick the perfect time for airfares, but we generally suggest the earlier, the better. Plenty of international flights on Expedia become available to compare up to a year in advance. If you're booking late, don't stress. Cheap prices occasionally appear within a few weeks of departure dates.
What does an Expedia São Francisco travel package include?
Expedia has everything you need to plan your São Francisco trip, but how you structure your package depends on you. Choose from any combination of hotels, rental cars and flights. After some tours or experiences to keep you on the go? Once you've made your booking, you can add them on too. Whatever your budget or style, there's a deal to meet your needs.
What should I know before booking a São Francisco travel package?
Bundling your bookings into a São Francisco vacation package is the easiest way to organize your trip. Not only that, you'll get great discounts when you combine your flights, hotels and car rentals. Once you've booked, why not add on a tour or an activity?
Can I choose my airline with a São Francisco Expedia vacation package?
With a vacation package, you're the one in charge. Whether you're eager to fly to São Francisco in first class or coach, simply select from the available airline options. Expedia has access to over 550 airline partners throughout the world.
If I'm not able to travel, can I cancel my São Francisco vacation package?
We get it — the universe can throw the odd curveball. If you've booked a São Francisco vacation package and have to amend or cancel it, we can help. We suggest looking up our Customer Service Portal first for information. But generally, if you've taken out your package within 24 hours, you may be able to cancel or change your itinerary at no cost. If it's been longer than 24 hours, your airline, hotel or car rental company may impose a charge.
Things to do
Manaus: Piranha Fishing and Alligator Watch Evening Tour
￥14,119
per adult
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.