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Our top choices for Santiago Sur hotels

A pool area with lounge chairs and a covered seating area, surrounded by modern buildings.
A modern hotel with a prominent entrance, outdoor seating area, and a handicap-accessible parking space.
A spacious lobby with modern seating, a central coffee table, and decorative hanging lights.
A spacious lobby with a central water feature, multiple seating areas, and a curved ceiling with hanging lights.

1. Hotel Mykonos Panama

Hotel Mykonos Panama
Nuevo Santiago
United States
Ismael
￥13,313
￥14,729 total
includes taxes & fees
Oct 7 - Oct 8
Hotel Mykonos Panama
A pool surrounded by palm trees and a tiled roof structure.
A spacious room with a high ceiling, a large window, and a wooden door leading to another area. There are several potted plants and a small table with a vase.
A hallway with a glass partition leading to a dining area, a stone wall, and a metal gate with decorative patterns.
A building with a curved facade, a balcony with metal railings, and a door with a sign.

2. Hotel Gran David

Hotel Gran David
Santiago
United States
Roxani
￥12,038
￥13,242 total
includes taxes & fees
Oct 7 - Oct 8
Hotel Gran David
A pool area with lounge chairs and umbrellas, surrounded by palm trees and a view of the beach.
A room with a sliding glass door leading to a balcony with a hammock.
A wooden building with a stone facade, a hammock, and potted plants.
A room with a bed, wooden walls, a TV, and a view of the outdoors.

3. Hotel y Restaurante Mama Ines

Hotel y Restaurante Mama Ines
Hicaco
Canada
OLIVER
￥11,217
￥12,339 total
includes taxes & fees
Oct 2 - Oct 3
Hotel y Restaurante Mama Ines
A modern lobby with a sofa, armchairs, a desk, and a large window offering a view of the cityscape.
A lobby with a reception desk, two armchairs, a sofa, and a table with a lamp.
A bathroom with a tiled shower wall, a sink, and a towel rack.
A hotel room with two single beds, a desk with a chair, a television, and a door.

4. Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes
Nuevo Santiago
United States
James
￥7,508
￥8,324 total
includes taxes & fees
Nov 1 - Nov 2
Hotel Plaza Los Tucanes
A rustic hut with a thatched roof, surrounded by lush greenery.
A wooden deck with a green cushioned bench, a potted plant, and a wooden table.
A pathway leading to a beach with palm trees and a view of the ocean.
A bedroom with a bed, curtains, a window, and a woven rug.

5. Casa Morrillo

Casa Morrillo
Torio
Canada
Adonis
￥10,639
￥11,703 total
includes taxes & fees
Oct 2 - Oct 3
Casa Morrillo
A modern poolside area with a bar and lounge seating, surrounded by palm trees.
A spacious living area with a large window, a wooden cabinet, and a cozy seating arrangement.
A bedroom with a large bed, a wooden wardrobe, and a view of the sea.
A bathroom with a large window, a hanging light fixture, and two large bowls on the floor.

6. Bambuda Santa Catalina

Bambuda Santa Catalina
Hicaco
United States
Dennis
￥10,955
￥12,172 total
includes taxes & fees
Oct 28 - Oct 29
Bambuda Santa Catalina
A modern house with a covered outdoor area, including a seating area and a table.
Dining
Living area
A wooden deck with a swimming pool, lounge chairs, and a large umbrella.

7. Sunhi Vista Eco-Resort

Sunhi Vista Eco-Resort
Torio
United States
Orlando
￥19,836
￥28,117 total
includes taxes & fees
Oct 2 - Oct 3
Sunhi Vista Eco-Resort
A swimming pool with a wooden deck and stairs leading to a covered area with a railing.
A lush garden with white flowers and green foliage, overlooking a rocky coastline and the sea.
A covered outdoor seating area with a view of the ocean.
A large house with a swimming pool surrounded by lush greenery and a view of the sea.

8. Punta Duarte Garden Inn

Punta Duarte Garden Inn
Torio
United States
Edgar
￥18,695
￥20,565 total
includes taxes & fees
Oct 9 - Oct 10
Punta Duarte Garden Inn
A clear pool with a tree in the center, surrounded by a stone deck.
A garden with a large fan palm tree, a stone wall, and a building with a red-tiled roof.
An interior view of a restaurant with a view of the ocean. There are wooden tables and chairs arranged for dining.
A beach with a boat, palm trees, and a small building.

9. Hotel Santa Catalina Panama

Hotel Santa Catalina Panama
Hicaco
United States
Brandon
￥16,365
￥18,002 total
includes taxes & fees
Oct 4 - Oct 5
Hotel Santa Catalina Panama
A beach with clear turquoise water, white sand, and lush green foliage including palm trees.
A person relaxing in a clear pool with a book, surrounded by lush greenery.
A stone wall with a rustic, natural look, a bench, and a glass door leading to an outdoor area with a tiled floor and greenery visible through the door.
A bedroom with a large bed, a desk, and a view of lush greenery through sliding glass doors.

10. Villa Coco

Villa Coco
Hicaco
Canada
Kyla
￥21,182
￥23,301 total
includes taxes & fees
Oct 16 - Oct 17
Villa Coco
A swimming pool with a thatched roof structure, palm trees, and a clear blue sky.
A room with a large window, a wicker chair, a small table, and a wall-mounted light fixture.
A room with a bed, a wooden nightstand, a door leading outside, and a window with curtains.
A covered outdoor seating area with wicker furniture, hanging lights, and potted plants.

11. HOTEL LAS HAMACAS

HOTEL LAS HAMACAS
Santa Catalina
￥20,074
￥22,522 total
includes taxes & fees
Oct 9 - Oct 10
HOTEL LAS HAMACAS
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Top Santiago Sur Hotel Reviews

Hotel Santa Catalina Panama

Hotel Santa Catalina Panama

8/10 Good
"The view amazing ... the kitchen wasn't available half of platea we order es"
Nicole Michelle 1-night trip
Posted 2 weeks ago
Hotel Santa Catalina Panama
Hotel y Restaurante Mama Ines

Hotel y Restaurante Mama Ines

8/10 Good
"loved the location and pool looking out at the beach, everything was great, except that the top bunk bed didn't have anything to stop someone from falling out so we couldn't use it"
Nicole 1-night trip
Posted 2 weeks ago
Hotel y Restaurante Mama Ines
Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes

10/10 Excellent
"Excelente"
Olopilel 1-night trip
Posted 1 month ago
Hotel Plaza Los Tucanes
Camino del Sol

Camino del Sol

10/10 Excellent
"Beautifully maintained property with very comfortable accommodations. The owner is very welcoming and full of great information and recommendations. Private beach makes you feel like you are in your own paradise! Restaurants are close by."
Amy 1-night trip
Posted 3 months ago
Camino del Sol
Casa Morrillo

Casa Morrillo

10/10 Excellent
"Yes, yes, yes! Absolutely adored my stay and was sad to leave."
Lorie 2-night trip
Posted 3 months ago
Casa Morrillo
Catalina's Hideaway

Catalina's Hideaway

10/10 Excellent
"La atención muy especial, el hotel divino y tranquilo, las camas cómodas y la comida excepcional 🙌"
Magda 3-night trip
Posted 4 months ago
Catalina's Hideaway
Torio guesthouse with panoramic view- Kokomo

Torio guesthouse with panoramic view- Kokomo

10/10 Excellent
"What a beautiful little Casita set overlooking the jungle and a view of the river. You can go out on your patio each morning and watch the sun come up and the mist rising from the valley. It is freaking amazing! The hosts were so helpful, friendly, and truly wonderful people. Whenever I go back to this area I will always check to see if their place is available first."
Scuba Rand 2-night trip
Posted 5 months ago
Torio guesthouse with panoramic view- Kokomo
Hotel Hibiscus Garden / Jardin De Papos

Hotel Hibiscus Garden / Jardin De Papos

10/10 Excellent
"This is a unique hotel. It's out of the way, on the edge of the jungle on a beautiful deserted beach. I walked for 5 km on the beach and saw 2 people, "
scott 4-night trip
Posted 8 months ago
Hotel Hibiscus Garden / Jardin De Papos
Susan Fish Camp in Playa Morrillo, Veraguas

Susan Fish Camp in Playa Morrillo, Veraguas

10/10 Excellent
"Fantastic place to stay in paradise! Look no further...this is the only place to stay if you're heading to Playa Morrillo area! "
David M. 4-night trip
Posted 1 year ago
Susan Fish Camp in Playa Morrillo, Veraguas

Frequently asked questions

What's the best place to stay in Santiago Sur?
Located 20.8 mi (33.5 km) from the heart of Santiago Sur, Hotel Mykonos Panama is a top choice for your stay based on our traveler data. Two other options for your visit to the area are Hotel Gran David and Bambuda Santa Catalina. See all available top hotels, or vacation rentals in Santiago Sur.
What are some of the best vacation rentals in Santiago Sur?
Susan Fish Camp in Playa Morrillo, Veraguas: This vacation home rental near Santiago Sur is located in the mountains and has a patio, a hot tub, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. See all vacation rentals in Santiago Sur.
If I need to cancel my hotel reservation in Santiago Sur, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santiago Sur.
Where can I learn more about changing or cancelling my trip to Santiago Sur?
For more information about updating your trip to Santiago Sur or cancelling it, click here.
What is staying in Santiago Sur like?
Travelers to Santiago Sur will find plenty to explore and enjoy. There are 57 hotels and other accommodations in the surrounding area. Find out more about Santiago Sur.
What is there to see in Santiago Sur?
Places to visit in the wider area include Torio Beach, Mariato Beach, and Lagartero Beach. Additionally, you'll find Torio Falls in the area. Check out what more to see and do in Expedia's Santiago Sur guide.
What's the seasonal weather like in Santiago Sur?
The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and December with an average of 77°F. The rainiest months in Santiago Sur are October, August, June, and November, with each month seeing an average of 18 inches of rainfall.