
Santi Cosma e Damiano Vacations from ¥180,522
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to ¥109,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
The Latest Santi Cosma e Damiano Vacation Packages
Price found within the past 48 hours. Click for updated prices.

Relais Castrum Boccea
Boccea
Price was ¥264,756, price is now ¥180,522 per person
¥180,522
per person
Sep 7 - Sep 10
found 1 day ago
Roundtrip non-stop flight included
Tokyo (TYO) to Rome (FCO)
8.6/10 Excellent! (318 reviews)
Extremely nice staff and very accommodating driver. Place is perfect for couples! Breakfast was very good. I would recommend renting a car if your planning on leaving outside of rome.
Reviewed on Jun 21, 2026

Albergo Etico Roma
Flaminio
Price was ¥393,140, price is now ¥227,243 per person
¥227,243
per person
Sep 7 - Sep 10
found 1 day ago
Roundtrip non-stop flight included
Tokyo (TYO) to Rome (FCO)
9.6/10 Exceptional! (366 reviews)
Fantastic one night stay!! Staff was friendly and welcoming, and the room was clean and relaxing! Overall would highly recommend.
Reviewed on Jun 12, 2026

GP Hotel
Collatino
Price was ¥278,220, price is now ¥181,829 per person
¥181,829
per person
Sep 7 - Sep 10
found 1 day ago
Roundtrip non-stop flight included
Tokyo (TYO) to Rome (FCO)
8/10 Very Good! (754 reviews)
Hotel location is not that convenient. Not a single train station is nearby. To go to any train station, you need to catch one of the buses. Even bus stops are at around 9 minutes walk. At night, coming back from those stops on the empty roads doesn't give safe vibes. Things that I thought were good; Maintenance is great. Staff is nice, and if you arrive before your check in time they allow you to put your luggage in the storage for free. Couple of supermarkets are nearby. Overall a decent hotel and stay.
Reviewed on Jun 17, 2026

Hotel Ludovisi Palace
Rome City Centre
Price was ¥335,803, price is now ¥219,889 per person
¥219,889
per person
Sep 7 - Sep 10
found 1 day ago
Roundtrip non-stop flight included
Tokyo (TYO) to Rome (FCO)
8.4/10 Very Good! (919 reviews)
Clean, great customer service, no charges for early arrival they kept my bags and when it was time to check in they moved them to the assigned room. Also, when it was time to leave the order a taxi for me.
The breakfast was delicious.
Reviewed on Jun 20, 2026

Hotel Tuscolana
San Giovanni
Price was ¥333,176, price is now ¥227,573 per person
¥227,573
per person
Sep 7 - Sep 12
found 10 hours ago
Roundtrip non-stop flight included
Tokyo (TYO) to Rome (FCO)
8.4/10 Very Good! (278 reviews)
Great location - close to the Metro and markets where the locals shop. The staff was extremely helpful - Chiara, Maria, Bruno, Danilo and others whose names I didn't get. Bruno suggested a great Italian restaurant, Osteria del Cavalierie which quickly became our favorite! I highly recommend this place.
Reviewed on Jun 11, 2026
Find the Best Santi Cosma e Damiano Vacation Packages
Santi Cosma e Damiano Hotel Deals

Grand Hotel Le Rocce
Via Flacca Km 23 Gaeta LT
Fully refundableReserve now, pay when you stay
The price is ¥79,777 per night from Jul 5 to Jul 6
¥79,777
¥89,235 total
Jul 5 - Jul 6
includes taxes & fees
9.8/10 Exceptional! (88 reviews)
"This place felt real special - the views were absolutely spectacular, the landscaping immaculate and the staff were most helpful. The choice of food available at breakfast was impressive and the restaurant at sunset was romantic. The stairs to and from the beach were a good form of exercise and the ..."
Reviewed on Jun 19, 2026

Hotel Mirasole International
Via Firenze, 5 Gaeta LT
The price is ¥33,455 per night from Jul 5 to Jul 6
¥33,455
¥38,280 total
Jul 5 - Jul 6
includes taxes & fees
8.6/10 Excellent! (303 reviews)
"Overall our stay was great! Loved the location, the pool, spa, breakfast. Rooms were a little small but had a fabulous balcony with a view of the ocean!"
Reviewed on Jun 11, 2026

Virgilio Grand Hotel
Viale Primo Romita 33 Sperlonga LT
Fully refundableReserve now, pay when you stay
The price is ¥45,247 per night from Jul 14 to Jul 15
¥45,247
¥51,066 total
Jul 14 - Jul 15
includes taxes & fees
8.4/10 Very Good! (294 reviews)
"Five-star experience! The staff were incredibly welcoming and attentive, making us feel right at home. We loved the flexible beach shuttle service; our driver even went out of his way to show us the route to our next day's tour port. Exceptional hospitality at reception, pristine amenities, and a ..."
Reviewed on Jun 17, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
