Santi Cosma e Damiano Vacations from ￥234,182
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to ￥45,448 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
The Latest Santi Cosma e Damiano Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Hotel Delle Civette
Nomentano
Price was ￥357,276, price is now ￥234,182 per person
￥234,182
per person
Mar 4 - Mar 10
found 1 day ago
Roundtrip non-stop flight included
Tokyo (HND) to Rome (FCO)
9.6/10 Exceptional! (267 reviews)
Excelente lugar en una area muy tranquila y cerca de lugares para ir a comer o cenar, su personal muy amable elvis, Diego todo si personal .🙏🙏🙏
Reviewed on Jan 17, 2026
EXE Domus Aurea
Rome City Centre
Price was ￥390,348, price is now ￥281,716 per person
￥281,716
per person
Apr 7 - Apr 14
found 23 hours ago
Roundtrip non-stop flight included
Osaka (OSA) to Rome (FCO)
8/10 Very Good! (490 reviews)
Everything was great. The check in process was fast. Enjoyed breakfast specially it was located on the rooftop. The room was always clean. Friendly and helpful staffs.
Reviewed on Dec 31, 2025
QC Grand Hotel Roma
Price was ￥352,439, price is now ￥259,782 per person
￥259,782
per person
Mar 3 - Mar 9
found 1 day ago
Roundtrip non-stop flight included
Osaka (OSA) to Rome (FCO)
9/10 Wonderful! (1,000 reviews)
If you’re looking to relax before you fly out after a long stay in Italy, this is the place to stay and recover before a long flight. I would recommend at least 2 nights to take advantage of their thermal pools and beautiful gardens. Enjoy
Reviewed on Jan 14, 2026
Find the Best Santi Cosma e Damiano Vacation Packages
Santi Cosma e Damiano Hotel Deals
Edra Palace
Via Ausonia angolo via Cerro Cassino FR
Fully refundableReserve now, pay when you stay
9/10 Wonderful! (167 reviews)
The staff was incredibly sweet and accommodating to our kids. Everything was clean and as it should be if a little outdated. The Christmas decorations in the lobby and garden were a real plus for the kids. Our waiter was especially wonderful at dinner and breakfast I wish i remembered his name. Great ...
Reviewed on Nov 29, 2025
Virgilio Grand Hotel
Viale Primo Romita 33 Sperlonga LT
Fully refundableReserve now, pay when you stay
The price is ￥21,339 per night from Feb 13 to Feb 14
￥21,339
￥23,474 total
Feb 13 - Feb 14
includes taxes & fees
8.4/10 Very Good! (288 reviews)
Staff was very helpful. Breakfast was amazing
Reviewed on Oct 8, 2025
Villa Maria Teresa Boutique Hotel
Viale Unità D'Italia 61 Formia LT
Fully refundableReserve now, pay when you stay
The price is ￥18,626 per night from Jan 31 to Feb 1
￥18,626
￥20,855 total
Jan 31 - Feb 1
includes taxes & fees
10/10 Exceptional! (9 reviews)
Fantastic set-up and view! Phenomenal rooms! Impeccable service!
Reviewed on Dec 3, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
